Home/GT Families/GT1/Alg13
Alg13
Mus musculus · UDP-N-acetylglucosamine transferase subunit ALG13 (EC 2.4.1.141)
GT1Non-model organism · annotation 4–5Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT1 · CAZy entry |
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| Gene symbol | Alg13 |
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| Synonyms / alternate names | Asparagine-linked glycosylation 13 homolog |
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| UniProt accession | Q9D8C3 |
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| NCBI Gene ID | 67574 |
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| Source species | Mus musculus |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | UDP-N-acetylglucosamine transferase subunit ALG13 (EC 2.4.1.141) |
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| Subcellular location | Endoplasmic reticulum membrane |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | Forms with ALG14 the active heterodimeric UDP-N-acetylglucos |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-glucosamine |
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| Donor CCD code(s) | UD1 |
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| Acceptor substrate(s) | - an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans
- poly-cis-dolichol
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
1166 aa
MKRAFVTVGTTSFDELVARVVANDCVQILESLGYNHLVLQVGRGTVVPKPFRTESFTLDVYRYKDSLKEDLQQADLVISHAGAGSCLESLEKGKPLVVVVNEKLMNNHQFELAKQLHKEGHLFYCTCRVLSCPAPVSLLLVLLGSAKILQQLPSATLSCFGYLPTQAPVLVATAYSYLHSVFSSFPPLSTFLIIPCTMQKGWKKYCGQKSLNEASMDEYLGSLGLFRKVVAKDASCLFRAISEQLFHSQIHHLQIRRACVSYMKENQQAFESYVEGSFEKYLERLGDPKESAGQLELKALSLIYNRDFIIYRYPGKPPTQVTDNGFEDKIILCYSNNGHYDSVYSKEFQSTAGICQAILYELLYKDVFVVDEETLKTAVDLFRSGSRRNKHHALTASVEGSSDQKSSTEDRTEEAAACSSAASTPEGNKQGTERQKVPESPSKMLFPYKVLKALDPEIYRNVEFDAWLDSRKELQKSECVEYGGRYYFLGDKCQVCMESGGKYYNAHIQEIDNDKSSVVVFIEEFAERHSIPLAHVRPVNQVALLPSWNAIPIRNGRGYPTITGGYFPEIVMTDMNMKQRKKMFKKFRGKEIYMTMAYSRGDPLVPSRIQHSMHYGHDPLLYYSQTAGHILSSQHFYPQHSSQRQGRGYGMPRDSSHLISKQNLPNPKVGFCSGSGRKCCQSYDNVSYRSRSFRRSHRQMHCMNKGCQYGFAPENGVEETVTFYALEEGNETAYSTLPNNGGPTTMVPATSGYCVARQGYNSCKPPLNSGDSNDHCDNGGYHGDYLYSSEQGYETSSVYTTTVSTANLSLQDSGPSSVPQDTVTSYNYPQKVLENSAAIAVSWASHVPVPVIPNCAGDNEALRTSDISSQNAIQPGFVPPPAQGSPAYLEPSAAGAAGAAAAAAAAAAPVATPVAAPLPLPPPLPPPPPATLEAGDASGFPLPPPPPPPPPPPPPYSYDPSGSDLPQDTKVLQYYFNLGLQCYHHNYWHPMVYMPHVQQQLQPQPQPQPQPQPQPQPQPQPQPQQPQQQQPPPQQQQQQQEQVHGESYPDCTEQPLVDQSAPQVYSDVVREDGTQADVSTNDTFPIADAVPLPHGAVYYPVMTDPYGSPLLGFDSYVPVASDYSSIAMWHPVNAACGASAQIHGAMNPGPIGYMLLPNSPHYTPQN
Catalytic domain sequence
130 aa
MDEYLGSLGLFRKVVAKDASCLFRAISEQLFHSQIHHLQIRRACVSYMKENQQAFESYVEGSFEKYLERLGDPKESAGQLELKALSLIYNRDFIIYRYPGKPPTQVTDNGFEDKIILCYSNNGHYDSVYS
