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desVII
Streptomyces venezuelae · 10-deoxymethynolide desosaminyltransferase (EC 2.4.1.277)
GT1Non-model organism · annotation 4–5Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT1 · CAZy entry |
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| Gene symbol | desVII |
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| Synonyms / alternate names | not curated |
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| UniProt accession | Q9ZGH7 |
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| NCBI Gene ID | not curated |
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| Source species | Streptomyces venezuelae |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | 10-deoxymethynolide desosaminyltransferase (EC 2.4.1.277) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | Forms a complex with DesVIII |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | dTDP-alpha-D-desosamine |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | 10-deoxymethynolide |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
426 aa
MRVLLTSFAHHTHYYGLVPLAWALLAAGHEVRVASQPALTDTITGSGLAAVPVGTDHLIHEYRVRMAGEPRPNHPAIAFDEARPEPLDWDHALGIEAILAPYFHLLANNDSMVDDLVDFARSWQPDLVLWEPTTYAGAVAAQVTGAAHARVLWGPDVMGSARRKFVALRDRQPPEHREDPTAEWLTWTLDRYGASFEEELLTGQFTIDPTPPSLRLDTGLPTVGMRYVPYNGTSVVPDWLSEPPARPRVCLTLGVSAREVLGGDGVSQGDILEALADLDIELVATLDASQRAEIRNYPKHTRFTDFVPMHALLPSCSAIIHHGGAGTYATAVINAVPQVMLAELWDAPVKARAVAEQGAGFFLPPAELTPQAVRDAVVRILDDPSVATAAHRLREETFGDPTPAGIVPELERLAAQHRRPPADARH
Catalytic domain sequence
410 aa
MRVLLTSFAHHTHYYGLVPLAWALLAAGHEVRVASQPALTDTITGSGLAAVPVGTDHLIHEYRVRMAGEPRPNHPAIAFDEARPEPLDWDHALGIEAILAPYFHLLANNDSMVDDLVDFARSWQPDLVLWEPTTYAGAVAAQVTGAAHARVLWGPDVMGSARRKFVALRDRQPPEHREDPTAEWLTWTLDRYGASFEEELLTGQFTIDPTPPSLRLDTGLPTVGMRYVPYNGTSVVPDWLSEPPARPRVCLTLGVSAREVLGGDGVSQGDILEALADLDIELVATLDASQRAEIRNYPKHTRFTDFVPMHALLPSCSAIIHHGGAGTYATAVINAVPQVMLAELWDAPVKARAVAEQGAGFFLPPAELTPQAVRDAVVRILDDPSVATAAHRLREETFGDPTPAGIVPEL
