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earP
Neisseria meningitidis serogroup B / serotype 15 (strain H44/76) · Protein-arginine rhamnosyltransferase (EC 2.4.1.-)
GT104Non-model organism · annotation 4–5Fold GT-BInverting5 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT104 · CAZy entry |
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| Gene symbol | earP |
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| Synonyms / alternate names | EF-P arginine rhamnosyltransferase |
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| UniProt accession | E6MVV9 |
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| NCBI Gene ID | not curated |
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| Source species | Neisseria meningitidis serogroup B / serotype 15 (strain H44/76) |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Protein-arginine rhamnosyltransferase (EC 2.4.1.-) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | 5WXI, 5WXJ, 5WXK, 5XVR, 7VCH |
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Donor and acceptor specificity
| Sugar nucleotide donor | dTDP-beta-L-rhamnose |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | L-arginyl-[protein] |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
382 aa
MNTPPFVCWIFCKVIDNFGDIGVSWRLARVLHRELGWQVHLWTDDVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDVVIETFACDLPENVLHIIRRHKPLWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYCEAVRFDTEALRERLMLPEKNASEWLLFGYRSDVWAKWLEMWRQAGSPMTLLLAGTQIIDSLKQSGVIPQDALQNDGDVFQTASVRLVKIPFVPQQDFDQLLHLADCAVIRGEDSFVRAQLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTPETVSAHRRLSDDLNGGEALSATQRLECWQTLQQHQNGWRQGAEDWSRYLFGQPSAPEKLAAFVSKHQKIR
Catalytic domain sequence
366 aa
IFCKVIDNFGDIGVSWRLARVLHRELGWQVHLWTDDVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDVVIETFACDLPENVLHIIRRHKPLWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYCEAVRFDTEALRERLMLPEKNASEWLLFGYRSDVWAKWLEMWRQAGSPMTLLLAGTQIIDSLKQSGVIPQDALQNDGDVFQTASVRLVKIPFVPQQDFDQLLHLADCAVIRGEDSFVRAQLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTPETVSAHRRLSDDLNGGEALSATQRLECWQTLQQHQNGWRQGAEDWSRYLFGQPSAPEKLAAFV
