Home/GT Families/GT11/F08A8.5
F08A8.5
Caenorhabditis elegans · Galactoside 2-alpha-L-fucosyltransferase (EC 2.4.1.-)
GT11Model organism · annotation ≥ 4Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT11 · CAZy entry |
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| Gene symbol | F08A8.5 |
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| Synonyms / alternate names | - Alpha-(1,2)-L-fucosyltransferase
- CE2FT-2
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| UniProt accession | A5Z2X3 |
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| NCBI Gene ID | 184168 |
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| Source species | Caenorhabditis elegans |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Galactoside 2-alpha-L-fucosyltransferase (EC 2.4.1.-) |
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| Subcellular location | - Golgi apparatus
- Golgi stack membrane
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | May form oligomers |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | not curated |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
402 aa
MRYNSNYLMYFCLVLGIFANIYVIIKITLGSSHILEYFQKNSNLSPKCEINVNNLLSFIENRHFLDLEQKNSQKSQPNYEKTLQLMLFAFPSGGLGNKLFEIISLHGIATSLQRKAVINATNPSFIETLNRNIQPLFPKLADQFTLRIIPDSLVTHQQTNWGRCCVYDDPSRFLNRSDQNLILDGHYFQSFKYFHHIRPQVREWLAPSKLQAMRAEILLPAKFRDDFLICTHVRRGDFQYDGLHRPSDATFTRAATDFLVDLYRKSHERVNVVVLGNDIHFAYTVFEDRVAHFTFLQKPVNNSYDYSLPQISPSYTAILTPTLTPEIDLAFSRLFCDVTLITAPSSTFGWWLSYLAKRTATTYYRDILESKDGVAGEMHPEDFYPPEWIKLKTDLNGKISKY
Catalytic domain sequence
291 aa
SGGLGNKLFEIISLHGIATSLQRKAVINATNPSFIETLNRNIQPLFPKLADQFTLRIIPDSLVTHQQTNWGRCCVYDDPSRFLNRSDQNLILDGHYFQSFKYFHHIRPQVREWLAPSKLQAMRAEILLPAKFRDDFLICTHVRRGDFQYDGLHRPSDATFTRAATDFLVDLYRKSHERVNVVVLGNDIHFAYTVFEDRVAHFTFLQKPVNNSYDYSLPQISPSYTAILTPTLTPEIDLAFSRLFCDVTLITAPSSTFGWWLSYLAKRTATTYYRDILESKDGVAGEMHPED
