Home/GT Families/GT11/SEC1
SEC1
Bos taurus · Galactoside 2-alpha-L-fucosyltransferase SEC1 (EC 2.4.1.-)
GT11Non-model organism · annotation 4–5Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT11 · CAZy entry |
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| Gene symbol | SEC1 |
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| Synonyms / alternate names | Secretory blood group protein 1 |
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| UniProt accession | Q9TTY3 |
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| NCBI Gene ID | not curated |
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| Source species | Bos taurus |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Galactoside 2-alpha-L-fucosyltransferase SEC1 (EC 2.4.1.-) |
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| Subcellular location | - Golgi apparatus
- Golgi stack membrane
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | GDP-beta-L-fucose |
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| Donor CCD code(s) | GFB |
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| Acceptor substrate(s) | a ganglioside GM1 |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
368 aa
MWDMRAVAPQRPAAGHPRAGWPRKLKTAATRFWATCPSSSTVCFLFVIFAVSTVFHCHRRLALVPAPWAYAGHVVLFPRHLPRGGVFTINAKGRLGNQMGEYATLYALAKMNGRAAFIPPQMHSTLAPIFRITLPVLHDATARSVPWQNYHLNDWMEEQYRHIPGEYVRLTGYPCSWTFYHHLRAEILQEFTLHAHVREEAQNFLRGLRVNGSRPSTYVGVHVRRGDYVRVMPTMWKGVLADRGYLQQALDWFRARHHSPLFVITSDDMAWCRRNINSSHRDVVFAGSGQQGSPARDFALLTQCNHTVITVGTFGIWAAYLAGGSTVYLANFTLPGSRFRMIFKPQAAFLPEWVGIAANLGQARESHP
Catalytic domain sequence
307 aa
VSTVFHCHRRLALVPAPWAYAGHVVLFPRHLPRGGVFTINAKGRLGNQMGEYATLYALAKMNGRAAFIPPQMHSTLAPIFRITLPVLHDATARSVPWQNYHLNDWMEEQYRHIPGEYVRLTGYPCSWTFYHHLRAEILQEFTLHAHVREEAQNFLRGLRVNGSRPSTYVGVHVRRGDYVRVMPTMWKGVLADRGYLQQALDWFRARHHSPLFVITSDDMAWCRRNINSSHRDVVFAGSGQQGSPARDFALLTQCNHTVITVGTFGIWAAYLAGGSTVYLANFTLPGSRFRMIFKPQAAFLPEWVGIA
