GT-CORE (public beta v1)

Glycosyltransferase Curated Online Resource for Enzymology

Family-organised sequence, structure, mechanism and substrate-specificity records for the CAZy glycosyltransferases

Saci_1262

Sulfolobus acidocaldarius DSM 639 · UDP-GlcNAc:Dol-PP-GlcNAc beta-1,4-GlcNAc-transferase (EC 2.4.1.-); transfers second GlcNAc in archaeal N-linked glycosylation pathway

GT115Model organism · annotation ≥ 4Fold GT-BInvertingannotation < 4

External resources

Identification and annotation

CAZy familyGT115 · CAZy entry
Gene symbolSaci_1262
Synonyms / alternate namesnot curated
UniProt accessionQ4J9C3
NCBI Gene IDnot curated
Source speciesSulfolobus acidocaldarius DSM 639
Taxonomic domainArchaea
UniProt annotation level1 below level 4

Function and localisation

Enzyme functionUDP-GlcNAc:Dol-PP-GlcNAc beta-1,4-GlcNAc-transferase (EC 2.4.1.-); transfers second GlcNAc in archaeal N-linked glycosylation pathway
Subcellular locationMembrane

Structure and mechanism

Fold typeGT-B
Catalytic mechanismInverting
Cation dependenceNo
Oligomeric statenot curated
PDB structuresnot curated

Donor and acceptor specificity

Sugar nucleotide donorUDP-N-acetyl-alpha-D-glucosamine
Donor CCD code(s)UD1
Acceptor substrate(s)Dolichyl-PP-GlcNAc (Dol-PP-GlcNAc)
Acceptor CCD / GlycoCTnot curated

Protein sequences

Full protein sequence

309 aa
MIDNPLLIIASGGGHTGFARAIAEYLPFKPDFVIPENDRFSKDMLLDYARKLYYVKKGKDVIVMNSSPDSILEFISDMYENDNLQFICDIAPIDYNQAVRNYPDFINKAIKPDIVLHMLDDFGKPRLYIQRQTNLKRVFKSQYLTLFSPEEFKNFLKRFNKKLIKVHPSSDIVKKLKEEGFSNELIQVKKKEPLLKKIPSPESIRQELEKRDKEFIDILDAIRENKLDINNIAYISNRSLSQISTLINEILENFQKQYQIISDINMRKEKYAQSIIKYLNKTLNQKNNNLTTFKEDFDNKFLSELKQIK

Catalytic domain sequence

not curated