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TOD1
Arabidopsis thaliana · Alkaline ceramidase TOD1 (EC 3.5.1.23)
GT116Model organism · annotation ≥ 4Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT116 · CAZy entry |
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| Gene symbol | TOD1 |
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| Synonyms / alternate names | Protein TURGOR REGULATION DEFECT 1 |
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| UniProt accession | Q6DBD7 |
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| NCBI Gene ID | 834664 |
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| Source species | Arabidopsis thaliana |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Alkaline ceramidase TOD1 (EC 3.5.1.23) |
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| Subcellular location | Golgi apparatus membrane |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Retaining |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | an N-acylsphing-4-enine |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
462 aa
MGKFITTTLSPPLYARSKLLCFSLLYLFSTIFLFLYVSLSRNQCIFRYSPFDPIQAKLFSYPSSYGEHKYALPTHRSSCSSPIFFSDYWTVLKEIQSILSGSSPKENLRYINGKSESFGGNFSTQKRFSYFNHSNIDVEVPCGFFRDFPVSNSDRVEMEKCGLVVASAIFNDHDKIRQPVGLGVKTLETVCFYMFIDDKTLNSLFHHNVILKNNPSDYRVGAWRIIKISKSENLYLNPAMNGVIPKYLIHRLFPNSKFSIWVDAKIQLMIDPLLLIHSMLVVPEVDMAISKHPFFVNTMEEAMATARWKKWGDVDGLRIQMETYCEHGLKPWSSSKLPYPTDVPDTALILRRHGIRSNLFSCFMFNELEAFNPRDQLAFAFVRDHINPKVKMNMFEVEVFEQVVVEYRHNLKKIESSTYEEQEEEQKQESLRTIQKRRKWLDHESWSLNRSSCKNYLTDMWG
Catalytic domain sequence
296 aa
KSESFGGNFSTQKRFSYFNHSNIDVEVPCGFFRDFPVSNSDRVEMEKCGLVVASAIFNDHDKIRQPVGLGVKTLETVCFYMFIDDKTLNSLFHHNVILKNNPSDYRVGAWRIIKISKSENLYLNPAMNGVIPKYLIHRLFPNSKFSIWVDAKIQLMIDPLLLIHSMLVVPEVDMAISKHPFFVNTMEEAMATARWKKWGDVDGLRIQMETYCEHGLKPWSSSKLPYPTDVPDTALILRRHGIRSNLFSCFMFNELEAFNPRDQLAFAFVRDHINPKVKMNMFEVEVFEQVVVEYRH
