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MNT2
Candida albicans (strain SC5314 / ATCC MYA-2876) · Glycolipid 2-alpha-mannosyltransferase 2 (EC 2.4.1.-)
GT15Non-model organism · annotation 4–5Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT15 · CAZy entry |
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| Gene symbol | MNT2 |
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| Synonyms / alternate names | - Alpha-1
- 2-mannosyltransferase 2
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| UniProt accession | P46592 |
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| NCBI Gene ID | 3636583 |
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| Source species | Candida albicans (strain SC5314 / ATCC MYA-2876) |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Glycolipid 2-alpha-mannosyltransferase 2 (EC 2.4.1.-) |
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| Subcellular location | Golgi apparatus membrane |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Retaining |
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| Cation dependence | Yes (Mn2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | not curated |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
461 aa
MKPSIFYSSRQPYLKYLAIILTTITIYVLTHSSYSADPNINDVTTKPISETVPQPPPQSPSSPEQQQQQPANQDQIVKVPEELKNKPQDLVVDNNKDQKPAVSGVPKSSSSSPQQQEKQDTKKESENSSSSKDPVKPEKVKATFVTLARNSELYDLIKSIRNVEDRFNRKFNYDWVFLNDDDFTQEFKDLTTALVSGKTKYGKIPKEHWSYPDWIDLKRAEETRKNMKLQKIIYGDSESYRHMCRFESGFFWRHPLLDDYDWYWRVEPSIDIHCDLNYDLFKYMEDNNKVYGFTISIHEFRATIPTLWDTTKKFIKENPQYLAENNFMDFISDDKGETYNLCHFWSNFEIANLNFWRGEAYRKYFDYLDQTGGFFYERWGDAPIHSIAAALFLPKDKIHYFDDVGYKHSVYTQCPLNPQFRYEHKCHCNPDNDFTFRGYSCGKKYFEKMGLQKPKEWEKYQ
Catalytic domain sequence
338 aa
SSPQQQEKQDTKKESENSSSSKDPVKPEKVKATFVTLARNSELYDLIKSIRNVEDRFNRKFNYDWVFLNDDDFTQEFKDLTTALVSGKTKYGKIPKEHWSYPDWIDLKRAEETRKNMKLQKIIYGDSESYRHMCRFESGFFWRHPLLDDYDWYWRVEPSIDIHCDLNYDLFKYMEDNNKVYGFTISIHEFRATIPTLWDTTKKFIKENPQYLAENNFMDFISDDKGETYNLCHFWSNFEIANLNFWRGEAYRKYFDYLDQTGGFFYERWGDAPIHSIAAALFLPKDKIHYFDDVGYKHSVYTQCPLNPQFRYEHKCHCNPDNDFTFRGYSCGKKYFEK
