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Alg9
Drosophila melanogaster · Alpha-1,2-mannosyltransferase Alg9 (EC 2.4.1.259; 2.4.1.261)
GT22 Model organism · annotation ≥ 4 Fold GT-C Inverting
External resources
Identification and annotation
CAZy family GT22 · CAZy entry Gene symbol Alg9 Synonyms / alternate names Dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase Dolichyl-P-Man:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase UniProt accession Q9VBV8NCBI Gene ID 43031Source species Drosophila melanogaster Taxonomic domain Eukaryota UniProt annotation level 4
Function and localisation
Enzyme function Alpha-1,2-mannosyltransferase Alg9 (EC 2.4.1.259; 2.4.1.261) Subcellular location Endoplasmic reticulum membrane
Structure and mechanism
Fold type GT-C Catalytic mechanism Inverting Cation dependence No Oligomeric state not curated PDB structures not curated
Donor and acceptor specificity
Sugar nucleotide donor not curated Donor CCD code(s) not curated Acceptor substrate(s) an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol Acceptor CCD / GlycoCT not curated
Protein sequences
Full protein sequence
623 aa
Copy
FASTA
MAPPAARARYIANKADNQILSKKPPKRPGLNGNNKTKEATPAGKKKDKDAKKRNQPTSGGQEKGLPNPIMPSVQTAFKTFVSARLCSAIWAYIADCDETFNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQGVPGYFYQKLFNPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFSVGMFVSSTALLPSSFSMYFGCAALAAWWQQNYCFAIFLTAISALLGWPFAALIGIPLVLEMLLRQRDWKTFVQWTLISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPNIFGTEPLSYYIINGFLNFNIIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYLWLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFFRMKSVVFKIKAGVHYLDHSMFIAILVMVTSTLLGLSRVFALYRNYHAPMDLMLELNQFKATPQYDPDVIYNVCIGKDWHRYPGSFFFPAKNFRLRFLKSEFRGMLPAYYDEGQNATKVVQPYFNDLNQENEHMYFDYDRCDFLVDFDEGKYTALEPNYSKRSKDWSVMKSLPFLIPEKSHKVLRAFYVPFLTDNHIQYGDFNLLKRKTKRNGR
Catalytic domain sequence
423 aa
Copy
FASTA
AFKTFVSARLCSAIWAYIADCDETFNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQGVPGYFYQKLFNPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFSVGMFVSSTALLPSSFSMYFGCAALAAWWQQNYCFAIFLTAISALLGWPFAALIGIPLVLEMLLRQRDWKTFVQWTLISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPNIFGTEPLSYYIINGFLNFNIIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYLWLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFFRMKSVVFKIKAGVHYLDHSMFIAILVMVTSTLLGLSRVFALYRNYHAPMDLMLELNQFKATPQYDPDVIYNVCIGKDWHRYPGSFFFP
