Home/GT Families/GT24/gpt1
gpt1
Schizosaccharomyces pombe (strain 972 / ATCC 24843) · UDP-glucose:glycoprotein glucosyltransferase (EC 2.4.1.-)
GT24Non-model organism · annotation 4–5Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT24 · CAZy entry |
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| Gene symbol | gpt1 |
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| Synonyms / alternate names | UDP--Glc:glycoprotein glucosyltransferase |
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| UniProt accession | Q09140 |
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| NCBI Gene ID | 2541413 |
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| Source species | Schizosaccharomyces pombe (strain 972 / ATCC 24843) |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | UDP-glucose:glycoprotein glucosyltransferase (EC 2.4.1.-) |
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| Subcellular location | Endoplasmic reticulum lumen |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Retaining |
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| Cation dependence | Yes (Ca2+, Mn2+) |
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| Oligomeric state | monomer |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | not curated |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
1448 aa
MRWGFWFAIATLITICYAAKPLDVKIAATFNAPSFSALIAESLYQEKKEGFIWYLNHLSDLLDAENTTEKELYINVVNSLKREYVLSDEELSSLQFSLGLFSGAPKLQAFSSIVQSRSCDCDTWLQLDEESQVCFSDLPKDSPLFSKLYSKNPLDYEVVKTSATGIPYAVVVTSFERDLIPFHELYYKLALEGKCNYVIRYSPPSSSKLNSKLYVKGFGTHVSLKRTDYLVVDDREFPREKGDNPASFTSSRNKRSNERLFGMTSDSLQTVTPDKIAILDLLATQSIASSTDMLTAFRELTQDFPIYAHYLSIQPDVSNDLIEELNQFQSQYVPEGINTIWLNGLSLDLEETDAFSILSLIKKEKDMFDRFEALGIKSSKVLDIVTNEAFANEDSDFKFVKFHCQDDIEDWKAIHWVNEIESNPKYDNWPKSIQILLKPIYPGQLHMLGKQLHTVIYPIFPSSPSSLPLLSELIQFSRRPSPVQTGMVCAANDDDEFAQTVCKSFFYISKESGTDSALKFLYKCLNSDSSADLYSLLEEHLPLSEHDDDTLANLKKDLSSSFFDHYMSKSNSWVNRLGIDSSASEVIVNGRIISHDENYDRSMYGIFLEDIPEVQIAVAEGKISEDDNLLDFILRDASLTRNPLVYPSAKSSIKSIDIKRVLENVGSLNHEDILLIGSSNAKYSFWLVADFNEKEGLEILSLLADLLSENKDANLMLIQEGKNHVVPPLFAKLLSSPKRSSKHLQEILNSSLDPSSGVVNDMDKALKFLKKSKAVVKELGLTGECKSALLLNGRMICSFSVDSLNTADLKMLMQMEYDNYLSKLSNIAGSSRRLKNSRAISFLSSYLKTLESTPMSTSSPTKEEKLFPRDFIYNKLGVGNATFETDDFSKAYYQFVAVLDPLSKDSQKWSAILEAVSKLNGVGVRIHFNPKQTLSELPLTRFYRYSISAEPEFDALGHLEESYVEFDNLPADTLLTMDIEARDAWTVMQKDVDIDLFNIKLEHTSEAEALDSHTAIYELKNILVQGYSQEEFRKSPPRGMQLKLGNLTNSHVTDTIVLSNLGYFQLKANPGVWTLEPMDGRSSQFYEILSLNKKNSYKDPQVIVDSFEGVTLNPVMRRKPGFESADIMDEDLSSHKFFDKIKKSLSFFNFKRKEASINIFSVASGHLYERFLYIMTKSVIEHTDKKVKFWFIENFLSPSFKSSIPAIAKKYNFEYEYITYNWPHWLRKQEEKQREIWGYKILFLDVLFPLELHKVIYVDADQIVRADLQELMDMDLHGAPYGYTPMCDSREEMEGFRFWKKGYWKKFLRGLKYHISALYVVDLDRFRKMGAGDLLRRQYQLLSADPNSLSNLDQDLPNHLQHLIPIYSLPQDWLWCETWCSDESLKTAKTIDLCQNPLTKEKKLDRARRQVSEWTSYDNEIASVLQTASSQSDKEFEEKDNNSSPDEL
Catalytic domain sequence
267 aa
INIFSVASGHLYERFLYIMTKSVIEHTDKKVKFWFIENFLSPSFKSSIPAIAKKYNFEYEYITYNWPHWLRKQEEKQREIWGYKILFLDVLFPLELHKVIYVDADQIVRADLQELMDMDLHGAPYGYTPMCDSREEMEGFRFWKKGYWKKFLRGLKYHISALYVVDLDRFRKMGAGDLLRRQYQLLSADPNSLSNLDQDLPNHLQHLIPIYSLPQDWLWCETWCSDESLKTAKTIDLCQNPLTKEKKLDRARRQVSEWTSYDNEIAS
