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tagA
Bacillus subtilis (strain 168) · N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase (EC 2.4.1.187)
GT26Model organism · annotation ≥ 4Fold NovelInverting
External resources
Identification and annotation
| CAZy family | GT26 · CAZy entry |
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| Gene symbol | tagA |
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| Synonyms / alternate names | - Major teichoic acid biosynthesis protein A
- N-acetylmannosaminyltransferase
- UDP-N-acetylmannosamine transferase
- UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase
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| UniProt accession | P27620 |
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| NCBI Gene ID | 936810 |
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| Source species | Bacillus subtilis (strain 168) |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase (EC 2.4.1.187) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | Novel |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-mannosamine |
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| Donor CCD code(s) | UD9 |
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| Acceptor substrate(s) | - N-acetyl-alpha-D-glucosaminyl-di-trans
- octa-cis-undecaprenyl diphosphate
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
256 aa
MQTETIHNIPYVNSNLTSFIDYLEKHYIDQKIGAVISTVNPEIAFAAIKDRDYFDVLSSSNFILPDGIGVVMMSRLTNNRLQSRIAGYDVFKELLGVANKKKKRIFLYGAKKDVIKGVVSKISSEYPNIKIAGYSDGYVQDRTLVAKQIARANPDMVFVALGYPHQEKFIHNYRHLFPKAVSIGLGGSFDVFSGNVKRAPSWMIRLNLEWFYRLILNPWRWKRMLSIPKYALTVLKEEKNKKTFYPKPEKDHTKQI
Catalytic domain sequence
168 aa
LSSSNFILPDGIGVVMMSRLTNNRLQSRIAGYDVFKELLGVANKKKKRIFLYGAKKDVIKGVVSKISSEYPNIKIAGYSDGYVQDRTLVAKQIARANPDMVFVALGYPHQEKFIHNYRHLFPKAVSIGLGGSFDVFSGNVKRAPSWMIRLNLEWFYRLILNPWRWKRM
