Home/GT Families/GT27/Galnt14
Galnt14
Mus musculus · Polypeptide N-acetylgalactosaminyltransferase 14 (EC 2.4.1.41)
GT27Non-model organism · annotation 4–5Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT27 · CAZy entry |
|---|
| Gene symbol | Galnt14 |
|---|
| Synonyms / alternate names | - Polypeptide GalNAc transferase 14
- Protein-UDP acetylgalactosaminyltransferase 14
- UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14
|
|---|
| UniProt accession | Q8BVG5 |
|---|
| NCBI Gene ID | 71685 |
|---|
| Source species | Mus musculus |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 5 |
|---|
Function and localisation
| Enzyme function | Polypeptide N-acetylgalactosaminyltransferase 14 (EC 2.4.1.41) |
|---|
| Subcellular location | Golgi apparatus membrane |
|---|
Structure and mechanism
| Fold type | GT-A |
|---|
| Catalytic mechanism | Retaining |
|---|
| Cation dependence | Yes (Mn2+) |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-galactosamine |
|---|
| Donor CCD code(s) | UD2 |
|---|
| Acceptor substrate(s) | - L-seryl-[protein]
- L-threonyl-[protein]
|
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
550 aa
MRRLTRRLALPIFGVLWITVLLFFWVTKRKLEVPLGPEVQTPKPSDADWDDLWEQFDERRYLNAKKWRVGDDPYKLYAFNQRESERISSNRAVPDTRHKRCSLLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPMHLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRMRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIINLDTFNYIESASELRGGFDWSLHFQWEQLSLEQKALRLDPTEPIRTPIIAGGLFVIDKAWFDYLGKYDVDMDIWGGENFEISFRVWMCGGGLEIIPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARPFALERPFGNIENRLNLRKNLHCQTFKWNLENVYPELRVPPDSSIQKGNIRQRQKCLESQKQKKQEILRLSPCAKVKGDGAKSQVWAFTYTQQIIQEELCLSVVTLFPGAPVVLALCKNGDERQLWTKTGARIEHIASHLCLDTDMFGDSTEDGKEVVVNPCESSLMSQHWDIVSS
Catalytic domain sequence
175 aa
SIIITFHNEARSTLLRTIRSVLNRTPMHLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRMRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIINLDTFNYIESASELRGGFDWSLHFQWEQLSLEQKALRLDPTEPIRTPIIAGGLFVID
