Home/GT Families/GT29/SMAX5B_019103
SMAX5B_019103
Scophthalmus maximus · Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
GT29Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT29 · CAZy entry |
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| Gene symbol | SMAX5B_019103 |
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| Synonyms / alternate names | not curated |
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| UniProt accession | A0A2U9C9T3 |
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| NCBI Gene ID | not curated |
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| Source species | Scophthalmus maximus |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) |
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| Subcellular location | - Cytoplasm
- Golgi apparatus membrane
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | CMP-N-acetyl-beta-neuraminate |
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| Donor CCD code(s) | NCC |
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| Acceptor substrate(s) | - (5Z,8Z,11Z,14Z)-eicosatetraenoate
- ATP
- CoA
- (E)-hexadec-2-enoate
- 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
- 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
- 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate
- a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))
- a beta-D-Gal-(1<->1')-ceramide
- a long-chain fatty acid
- ganglioside GA1 (d18:1(4E)/18:0)
- ganglioside GA2 (d18:1(4E)/18:0)
- hexadecanoate
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
1763 aa
MRLSLRWAAHRYVFVVGVVLGLLGLVMVSLPLNGTRTTKPLNWHVSPAHKKLVQEHVLRVLEGRCRPGSTRQSLLARLPASGSVDQPFLWKDGPLPDHLFRDPPPFGFRGVRAKVDDLLKLLEHSDVAHQPGKTSAKCQRCVVVGNGGILRGLELGPLIDRFDTIIRLNSGPLGAFSVDVGNRTSIRMSYPEGTPLHWIDTDPHTLFVAVVYKSVDISWISAMINKLAVSLWDRLFFWQKVPQQIPLEPRRFRLLNPHVIRETALDLLRYPPPRPRLFGWDKNVPTLGVSALNLASLLCDEVSLAGFGYNLSQQGALLHYYDHLPMSAMLRQKMHNVDRETELLQNLLLSDSISSSQLTTRRVTTHGSLGESSSSSSSSSSIMLSPDTFQRLRLPDMDDVGQYIRSVPTPVFVGVGAVAAATAYYLATRPATLPSVCDLHMQSVEVPGKDFERRSVLQNGNGHLTHVYDDGRTLYEFFLRGVRISNNGPCLGSRKPKQPYEWMSYREVMERTENLGSAFLHKGHSKTTDPHIGIFSQNRPEWTISELACYTYSLVSVPLYDTLGTEAISYILDKACISTIVCDVADKVNLVLDCTKDRKHNVRTIVLMETPSAELVTRGRQAGIHILSLQEMEAIGKANHHQPVPPQPEDMAVICFTSGTTGDPKGAMLTHGNIVSNCSAFIKLTERHCLFSDSDVHISFLPLAHMFERVTQGVMIVHGASIGFFQGDIRRLTDDLNTLRPTVFPVVPRLLNRMYDKIFGQANTSLKRWLLGFAYRRKEAELMKGIVRRDSIWDRLIFGKVQASLGGRVRLMFTGAAPISPTVLTFLRAAIGCQFYEGYGQTECTAGCTMNLPGDWSAGHVGAPLPCNSIKLVDVPEMNYLAVNGEGEVCVKGANVFQGYLKDPAKTAETIDAEGWVHTGDIGKWLPNGTLRIVDRKKHIFKLAQGEYIAPEKIETIYLRSDAVAQVFVHGDSLQACLVAVVVPDHDFLSGWTKKTLRLEGSYQELCGREEVKAAILEDMLRLGKEGGLKSFEQARAIHIHSELFSIENGLLTPTLKAKRNCLRQHFRSQIEELYAGITIAKKGRGAKVPAGPPDQRQASSRDVAEAPNVSAIDKTSFLEALQLNDGNPLHSTAMEEELNVLEEGRVDRGKAGRPNDPRTLKAKQRGAAAKRKATETDEENGEEEEKKRTRRSTGEKVKARPDKGGERKKKKAEPEVPVGAVSSSDADSTPHTSSQPASRANRHLVGKKPAKRRSAGKTTAVRPLKRQQTTKDTKRRSESDIEKSNDPESQEESDTGADQQSRKRVLSSDEEVEEEKSWKPSPKEARVYRFVSSRKSSSGSASAGAGRSDTDKQRSKRPARQAGTNLEVVLDAFLDFCDQYRESVESKAVKQSIDSFSSHVKEQLLEKISSDKELRVLKRENAKVGSLIRTKTQRMLDAKHELMREGDRPAQTHLHGPVAKERNMAEVHDDGDKPIAGDTVDALKQFTKRSKAETTGSSGSTEEVDSTPSSRDSSAAGSDPHRYRMDYPSMGTCVIINNKNFHSSTNMSARNGTDVDAAIAMKTFSDLGYKLKVANDQTVKKMKQLLSNVSEEDHSGSASFACVLLSHGDNGVIYGTDGCEMIENLTKYFKGDRCKSLVGKPKLFFIQACRGTALDDGAIYETDSVDEQTSERIPVEADFLYAYSTAPGYYSWRNTGNGSWFMQAMCEMLQQYRGELELMQIMTRVNRKVALHFESASNLPGYSGKKQIPCIVSMLTKDFYFP
Catalytic domain sequence
257 aa
KDGPLPDHLFRDPPPFGFRGVRAKVDDLLKLLEHSDVAHQPGKTSAKCQRCVVVGNGGILRGLELGPLIDRFDTIIRLNSGPLGAFSVDVGNRTSIRMSYPEGTPLHWIDTDPHTLFVAVVYKSVDISWISAMINKLAVSLWDRLFFWQKVPQQIPLEPRRFRLLNPHVIRETALDLLRYPPPRPRLFGWDKNVPTLGVSALNLASLLCDEVSLAGFGYNLSQQGALLHYYDHLPMSAMLRQKMHNVDRETELLQNL
