Home/GT Families/GT29/SiaT
SiaT
Drosophila melanogaster · beta-galactoside alpha-(2,6)-sialyltransferase (EC 2.4.3.1)
GT29Model organism · annotation ≥ 4Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT29 · CAZy entry |
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| Gene symbol | SiaT |
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| Synonyms / alternate names | - D.SialT
- D.SiaT
- Dm ST
- Dmel\CG4871
- DmPST
- DmSialT
- DSiaT
- dSiaT
- dST6Gal I
- SialT
- ST
- ST6GAL
- ST6Gal
- St6Gal
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| UniProt accession | Q9W121 |
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| NCBI Gene ID | 37950 |
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| Source species | Drosophila melanogaster |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | beta-galactoside alpha-(2,6)-sialyltransferase (EC 2.4.3.1) |
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| Subcellular location | - Golgi apparatus
- Golgi stack membrane
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | not curated |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
451 aa
MRQVTRASSGQSQALLSCLIIAVCAALIIQSGHIQGVKAQPGREPGEVNSRQPGNGNGTTGHRVPRSVFHVRWNPNEKFIVESRENPAINSSKLAPHPRLKVSKNTKLTLSPKLYLCHDKHSELCHNKTQQFRQRIVRAFEKAMVESVNESQANHYNVDYKPVFGDSFEEQYYPSTCLVMEAGVRVLRRKDAPFNKLPFGRLFPRQKLFRNVKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTTIRVVNSQVVTKPEFDFTRAPIFRNVTIAAWDPGKYNGTLEDWLTSADYDLFSNYELYRRRYPKSRAFLIDPHSVWRLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFVEYVPSTRLNGRCHYYSKEMNSACTFGSWHPLAAEKLMALDMNMAEDDDMSVFQFGILRIRRPDKLLCGFNFFGY
Catalytic domain sequence
208 aa
NVKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTTIRVVNSQVVTKPEFDFTRAPIFRNVTIAAWDPGKYNGTLEDWLTSADYDLFSNYELYRRRYPKSRAFLIDPHSVWRLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFVEYVPSTRLNGRCHYYSKEMNSACTFGSWHPLAAEKLMALDM
