Home/GT Families/GT3/GSY2
GSY2
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) · Glycogen [starch] synthase isoform 2 (EC 2.4.1.11)
GT3Model organism · annotation ≥ 4Fold GT-BRetaining16 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT3 · CAZy entry |
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| Gene symbol | GSY2 |
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| Synonyms / alternate names | not curated |
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| UniProt accession | P27472 |
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| NCBI Gene ID | 850962 |
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| Source species | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Glycogen [starch] synthase isoform 2 (EC 2.4.1.11) |
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| Subcellular location | |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Retaining |
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| Cation dependence | No |
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| Oligomeric state | Interacts with PCL10 |
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| PDB structures | 3NAZ, 3NB0, 3NCH, 3O3C, 3RSZ, 3RT1, 4KQ2, 4KQM, 5SUK, 5SUL, 5UW0, 5UW1, 5UW4, 5UX7, 5VNC, 6U77 |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-glucose |
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| Donor CCD code(s) | UPG |
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| Acceptor substrate(s) | [(1->4)-alpha-D-glucosyl](n) |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
705 aa
MSRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALAGGKKLKVARPLSVPGSPRDLRSNSTVYMTPGDLGTLQEVNNADDYFSLGVNPAADDDDDGPYADDS
Catalytic domain sequence
470 aa
DAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVK
