Home/GT Families/GT41/GL50803_12081
GL50803_12081
Giardia intestinalis (strain ATCC 50803 / WB clone C6) · UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (EC 2.4.1.255)
GT41Non-model organism · annotation 4–5Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT41 · CAZy entry |
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| Gene symbol | GL50803_12081 |
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| Synonyms / alternate names | - O-linked GlcNAc transferase
- O-linked N-acetylglucosaminyltransferase
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| UniProt accession | A8BFN4 |
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| NCBI Gene ID | 5700203 |
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| Source species | Giardia intestinalis (strain ATCC 50803 / WB clone C6) |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (EC 2.4.1.255) |
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| Subcellular location | |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-glucosamine |
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| Donor CCD code(s) | UD1 |
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| Acceptor substrate(s) | - L-seryl-[protein]
- L-threonyl-[protein]
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
1480 aa
MVALMDKIAQLFRNKQYSDLIQLIDKQLHAKNEPEALIFLYAIQGEISFKQKDWIQAFAAYEKAVAESKQKGLPTQVYAQIVQRQMIILLRLQMLDTAFGLFSENQSVSVDNVQVLAQLALLYLMCERYSEAEKLLSSIVESSTSNTITLSKQFKEDIGPFKELFGVLDTYDTFLATILNNLAICNSKLGNHTLAFDQFQQALDIIKDPEKITRPPLSPITVLFDNCVSTVDEDKEKALKVEHHMLTINESKENQEDDTVLSLLRDGCTLIPSSTLGTHLPLIIELHSTICYNIGKLELTLGNLDRSVNHFKKSIEYQPSFARYVALGLVYRDMRNFYDAAEMLTKAVDSCVGISNLCLGEVVYNLGILVSEELKMPYKSLQFFDEATVLFIRGEFSAGAILSRIMKANSLTTITTATAVSSDWEFIMAFLNTLYLDLCAFSKDQGFNVEAAFTGTNAISFNLPITEPQEKESPKSDKIASEKPLVESNPGRSRTPSSMNDVYMLSAENLSFSLLESSFAQKETITSRLFPTFQAETKRYLAILYTNLGLIYYRIGIPTYYKQARRCFEVAIWFDNDCVFAINYLSVLLLKENSKTLAIEGLLKCTRLFPEYYEPFYNLGNILKADEENKKALQYYSRAIELNPRFLDGYLARGVLYAELHRFETAYLDFSKCIELDPDNRHAFCNYIHMKQILGIFHNDTLDMRKISKIIDDYIHEYLTVQNAINKGVVLPSHPLPPIMPYHCYLYRLSSSQLRFICQRYSEQNVNWVKQNIDMMSTPLLDLSIHQRPMPPSIGLINSVSSSSQLQLSMLPLNQSAADSMVPLAMLTPGPTLCTAIGFQSIKSVIRDSQHITHGPIFSYDRALITLARSKHSSKCPISYIDIVNLKSPLRLGVLCDDINSIPIGCILESWLRNIDPKVASLSIYSTVASDKSALRTSLEAHCSNFIDFTNYKYQNNPFLCAQRINGDGICIMISMCQHNCGLEGRILAMRPAPIQISYWTHGGTTNSNYLDYILADQYCIPPGYAHLYSEHVITMPGCFICPSHSMHYSNAILLEEHADILKVTVEEVRSLIQDSKPDIDVNHHSAAGENILSLDGSDATSSSVDSGIGSRTHSEAPIGGGDKDEGAHSSKILELELELAEIAKMKGETKNGVSTNSASEGRDELLMNDRILITGDNVFFQVQPIRNGRLVGGRDRSMIKKMEPLLKAIYPLQRIASEAAVPASMEKSENNSDLTSHRVCLELPLYRKNIRALYGIPANCFLFCTFNQVYKFDMGTLGIIAALLRSVPNAYYALLKFPPASQLHIEAFFRHKAPDILDRVIFLSMLPMKVEHIRRYLAVDVFVDTLKCNGSTIVLDALWSGVPVVGFVGEYILSRKTLSFLSVLECKDLICASQGEAVLLCTRLAVDSGYYFSVRKRILKNRSNLFNISRWCDNFVLTMMLAYKNWIFGGKPTSFSTERVIANVKSQGFSWPLKSTGAQ
Catalytic domain sequence
562 aa
SKCPISYIDIVNLKSPLRLGVLCDDINSIPIGCILESWLRNIDPKVASLSIYSTVASDKSALRTSLEAHCSNFIDFTNYKYQNNPFLCAQRINGDGICIMISMCQHNCGLEGRILAMRPAPIQISYWTHGGTTNSNYLDYILADQYCIPPGYAHLYSEHVITMPGCFICPSHSMHYSNAILLEEHADILKVTVEEVRSLIQDSKPDIDVNHHSAAGENILSLDGSDATSSSVDSGIGSRTHSEAPIGGGDKDEGAHSSKILELELELAEIAKMKGETKNGVSTNSASEGRDELLMNDRILITGDNVFFQVQPIRNGRLVGGRDRSMIKKMEPLLKAIYPLQRIASEAAVPASMEKSENNSDLTSHRVCLELPLYRKNIRALYGIPANCFLFCTFNQVYKFDMGTLGIIAALLRSVPNAYYALLKFPPASQLHIEAFFRHKAPDILDRVIFLSMLPMKVEHIRRYLAVDVFVDTLKCNGSTIVLDALWSGVPVVGFVGEYILSRKTLSFLSVLECKDLICASQGEAVLLCTRLAVDSGYYFSVRKRILKNRSNLFNISRWCDN
