Home/GT Families/GT41/sxc
sxc
Drosophila melanogaster · UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255)
GT41Model organism · annotation ≥ 4Fold GT-BInverting1 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT41 · CAZy entry |
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| Gene symbol | sxc |
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| Synonyms / alternate names | - CG10392-RC
- Ogt
- O-GlcNAc transferase subunit p110
- O-linked N-acetylglucosamine transferase 110 kDa subunit
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| UniProt accession | Q7KJA9 |
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| NCBI Gene ID | 35486 |
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| Source species | Drosophila melanogaster |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) |
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| Subcellular location | |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | 5A01 |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | not curated |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
1059 aa
MHVEQTRINMQSQGQSHQLPSAAHILLDQNPNSTGSNLVVKQNDIQSLSSVGLLELAHREYQAVDYESAEKHCMQLWRQDSTNTGVLLLLSSIHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDIRMKKLVSIVTEQLEKNRLPSVHPHHSMLYPLTHDCRKAIAARHANLCLEKVHVLHKKPYNFLKKLPTKGRLRIGYLSSDFGNHPTSHLMQSVPGLHDRSKVEIFCYALSPDDGTTFRHKISRESENFVDLSQIPCNGKAADKIFNDGIHILVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDSVTSPLELAYQYSEKLSYMPHTYFIGDHKQMFPHLKERIIVCDKQQSSVVDNVTVINATDLSPLVENTDVKEIKEVVNAQKPVEITHKVAELPNTTQIVSMIATGQVQTSLNGVVVQNGLATTQTNNKAATGEEVPQNIVITTRRQYMLPDDAVVYCNFNQLYKIDPQTLESWVEILKNVPKSVLWLLRFPAVGEQNIKKTVSDFGISPDRVIFSNVAAKEEHVRRGQLADICLDTPLCNGHTTSMDVLWTGTPVVTLPGETLASRVAASQLATLGCPELIARTREEYQNIAIRLGTKKEYLKALRAKVWKARVESPLFDCSQYAKGLEKLFLRMWEKYENGELPDHISAV
Catalytic domain sequence
531 aa
VCDWTDYDIRMKKLVSIVTEQLEKNRLPSVHPHHSMLYPLTHDCRKAIAARHANLCLEKVHVLHKKPYNFLKKLPTKGRLRIGYLSSDFGNHPTSHLMQSVPGLHDRSKVEIFCYALSPDDGTTFRHKISRESENFVDLSQIPCNGKAADKIFNDGIHILVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDSVTSPLELAYQYSEKLSYMPHTYFIGDHKQMFPHLKERIIVCDKQQSSVVDNVTVINATDLSPLVENTDVKEIKEVVNAQKPVEITHKVAELPNTTQIVSMIATGQVQTSLNGVVVQNGLATTQTNNKAATGEEVPQNIVITTRRQYMLPDDAVVYCNFNQLYKIDPQTLESWVEILKNVPKSVLWLLRFPAVGEQNIKKTVSDFGISPDRVIFSNVAAKEEHVRRGQLADICLDTPLCNGHTTSMDVLWTGTPVVTLPGETLASRVAASQLATLGCPELIARTREEYQNIAIRLGTKKEYLKALRAKVWKARVESPLFDCSQYAKG
