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glgA
Escherichia coli (strain K12) · Glycogen synthase (EC 2.4.1.21)
GT5Model organism · annotation ≥ 4Fold GT-BRetaining7 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT5 · CAZy entry |
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| Gene symbol | glgA |
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| Synonyms / alternate names | Starch [bacterial glycogen] synthase |
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| UniProt accession | P0A6U8 |
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| NCBI Gene ID | 75173587; 75202274; 947932 |
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| Source species | Escherichia coli (strain K12) |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Glycogen synthase (EC 2.4.1.21) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Retaining |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | 2QZS, 2R4T, 2R4U, 3COP, 3CX4, 3D1J, 3GUH |
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Donor and acceptor specificity
| Sugar nucleotide donor | ADP-alpha-D-glucose |
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| Donor CCD code(s) | ADQ |
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| Acceptor substrate(s) | [(1->4)-alpha-D-glucosyl](n) |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
477 aa
MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
Catalytic domain sequence
151 aa
VDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRA
