Home/GT Families/GT54/Mgat4d
Mgat4d
Mus musculus · Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
GT54Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT54 · CAZy entry |
|---|
| Gene symbol | Mgat4d |
|---|
| Synonyms / alternate names | N-acetylglucosaminyltransferase MGAT1 inhibitory protein |
|---|
| UniProt accession | Q9D4R2 |
|---|
| NCBI Gene ID | 67555 |
|---|
| Source species | Mus musculus |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 5 |
|---|
Function and localisation
| Enzyme function | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D |
|---|
| Subcellular location | - Endoplasmic reticulum membrane
- Endoplasmic reticulum-Golgi intermediate compartment membrane
- Golgi apparatus membrane
|
|---|
Structure and mechanism
| Fold type | GT-A |
|---|
| Catalytic mechanism | Inverting |
|---|
| Cation dependence | Yes (Mn2+) |
|---|
| Oligomeric state | Isoform 2 self-associates; specifically in the endoplasmic r |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
|---|
| Donor CCD code(s) | not curated |
|---|
| Acceptor substrate(s) | not curated |
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
373 aa
MKAKNVNLLFAFVAVLLFGFSCFCISRMNQTNNQLINCRNHVLEFKEIMLRLKNKSENHHQDLMQVLYQMKRKAAHTTRSSGNFLEKKGSILSQHETLPNQFEVLKYFLPHLRTAGKLYPAIATSKGRAGVSFALGISTINRGNHTYLKQTLTSVLSRMTPEEEEDSVVIVSVADTDESYLKSVVRMVKTKFRKQVQSGVLEVISIPTLFYPQTLLDKKTKTDSESWQIKQVLDFCILMLYAQPKATYYLQLEDDIVAKKMYFTKMKDFVNSLTSKNWFFIEFSVLGFIGKLFRSKDLTDFVHFFLMFYETKPIDILLDDIFLIRVCISGEPVRSCLQRKKGFRIQYRPSLFQHVGTQSSFPGREQHLKDNYY
Catalytic domain sequence
276 aa
LPNQFEVLKYFLPHLRTAGKLYPAIATSKGRAGVSFALGISTINRGNHTYLKQTLTSVLSRMTPEEEEDSVVIVSVADTDESYLKSVVRMVKTKFRKQVQSGVLEVISIPTLFYPQTLLDKKTKTDSESWQIKQVLDFCILMLYAQPKATYYLQLEDDIVAKKMYFTKMKDFVNSLTSKNWFFIEFSVLGFIGKLFRSKDLTDFVHFFLMFYETKPIDILLDDIFLIRVCISGEPVRSCLQRKKGFRIQYRPSLFQHVGTQSSFPGREQHLKDNYY
