Home/GT Families/GT55/mngA
mngA
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) · Mannosyl-3-phosphoglycerate synthase (EC 2.4.1.217)
GT55Model organism · annotation ≥ 4Fold GT-ARetainingannotation < 4
External resources
Identification and annotation
| CAZy family | GT55 · CAZy entry |
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| Gene symbol | mngA |
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| Synonyms / alternate names | not curated |
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| UniProt accession | Q8U380 |
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| NCBI Gene ID | 13302403 |
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| Source species | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
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| Taxonomic domain | Archaea |
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| UniProt annotation level | 2 below level 4 |
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Function and localisation
| Enzyme function | Mannosyl-3-phosphoglycerate synthase (EC 2.4.1.217) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Retaining |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | GDP-alpha-D-mannose |
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| Donor CCD code(s) | GDD |
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| Acceptor substrate(s) | (2R)-3-phosphoglycerate |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
394 aa
MLLEAPVYKEIFGAVKIYELQKVIKLDTETEDVPVYTITNIPREKIYDTLGKMAVIVPMKNEKLHLVDGVLKAIPHKCPIIIVSNSKREGPNRYRLEVDLVRHFYNLTNSKIIMVHQRDPGLAKAFQKVGYTDILDEKGNIRSGKGEGMLIGILLAKAIGAEYVGFVDADNYIPGAVNEYVKDYAAGFLMSESDYTMVRLHWRHKPKVTKGTLYFKKWGRVSEITNHYLNMLISEQTSFETTIMVTGNAGEHAMTMKLAEIMPFSTNYSIEPYEIVYLLERFGKWENVEEFKDVFDQGIEIFQIETLNPHFHEDKGQEHVREMILLSLATIYHSKMASKNLKRRILNDLIEHGILKEGEEPPKLRIMRPINEIDIEEWMKVVENNSETLLRFGL
Catalytic domain sequence
376 aa
PVYKEIFGAVKIYELQKVIKLDTETEDVPVYTITNIPREKIYDTLGKMAVIVPMKNEKLHLVDGVLKAIPHKCPIIIVSNSKREGPNRYRLEVDLVRHFYNLTNSKIIMVHQRDPGLAKAFQKVGYTDILDEKGNIRSGKGEGMLIGILLAKAIGAEYVGFVDADNYIPGAVNEYVKDYAAGFLMSESDYTMVRLHWRHKPKVTKGTLYFKKWGRVSEITNHYLNMLISEQTSFETTIMVTGNAGEHAMTMKLAEIMPFSTNYSIEPYEIVYLLERFGKWENVEEFKDVFDQGIEIFQIETLNPHFHEDKGQEHVREMILLSLATIYHSKMASKNLKRRILNDLIEHGILKEGEEPPKLRIMRPINEIDIEEWMKV
