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alg6
Schizosaccharomyces pombe (strain 972 / ATCC 24843) · Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267)
GT57 Non-model organism · annotation 4–5 Fold GT-C Inverting
External resources
Identification and annotation
CAZy family GT57 · CAZy entry Gene symbol alg6 Synonyms / alternate names Asparagine-linked glycosylation protein 6 Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase UniProt accession O43053NCBI Gene ID 2540993Source species Schizosaccharomyces pombe (strain 972 / ATCC 24843) Taxonomic domain Eukaryota UniProt annotation level 4
Function and localisation
Enzyme function Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) Subcellular location Endoplasmic reticulum membrane
Structure and mechanism
Fold type GT-C Catalytic mechanism Inverting Cation dependence No Oligomeric state not curated PDB structures not curated
Donor and acceptor specificity
Sugar nucleotide donor not curated Donor CCD code(s) not curated Acceptor substrate(s) an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate Acceptor CCD / GlycoCT not curated
Protein sequences
Full protein sequence
506 aa
Copy
FASTA
MLSEFENGAPVQQFVSRFRSYSSKFLFFPCLIMSLVFMQWLISIGPYSGYNTPPMYGDFEAQRHWMELTLHTPVSQWYFRDLQWWGLDYPPLTAYVSWFFGIIGHYFFNPEWFADVTSRGFESLELKLFMRSTVIASHLLILVPPLMFYSKWWSRRIPNFVDRNASLIMVLFQPALLLIDHGHFQYNCVMLGLVMYAIANLLKNQYVAATFFFCLALTFKQMALYFAPPIFFYLLGTCVKPKIRFSRFILLSVTVVFTFSLILFPWIYMDYKTLLPQILHRVFPFARGLWEDKVANFWCTLNTVFKIREVFTLHQLQVISLIFTLISILPSCVILFLYPRKRLLALGFASASWGFFLFSFQVHEKSVLLPLLPTSILLCHGNITTKPWIALANNLAVFSLWPLLKKDGLGLQYFTLVLMWNWIGDMVVFSKNVLFRFIQLSFYVGMIVILGIDLFIPPPSRYPDLWVILNVTLSFAGFFTIYLWTLGRLLHISSKLSTDLRNKKEA
Catalytic domain sequence
448 aa
Copy
FASTA
FMQWLISIGPYSGYNTPPMYGDFEAQRHWMELTLHTPVSQWYFRDLQWWGLDYPPLTAYVSWFFGIIGHYFFNPEWFADVTSRGFESLELKLFMRSTVIASHLLILVPPLMFYSKWWSRRIPNFVDRNASLIMVLFQPALLLIDHGHFQYNCVMLGLVMYAIANLLKNQYVAATFFFCLALTFKQMALYFAPPIFFYLLGTCVKPKIRFSRFILLSVTVVFTFSLILFPWIYMDYKTLLPQILHRVFPFARGLWEDKVANFWCTLNTVFKIREVFTLHQLQVISLIFTLISILPSCVILFLYPRKRLLALGFASASWGFFLFSFQVHEKSVLLPLLPTSILLCHGNITTKPWIALANNLAVFSLWPLLKKDGLGLQYFTLVLMWNWIGDMVVFSKNVLFRFIQLSFYVGMIVILGIDLFIPPPSRYPDLWVILNVTLSFAGFFTIYLW
