Home/GT Families/GT60/gnt1
gnt1
Dictyostelium discoideum · [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase (EC 2.4.1.229)
GT60Model organism · annotation ≥ 4Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT60 · CAZy entry |
|---|
| Gene symbol | gnt1 |
|---|
| Synonyms / alternate names | - gnt51
- gntA
- Glycosyltransferase GnT51
- Skp1-HyPro GlcNAc-transferase
- UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase
- UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase
|
|---|
| UniProt accession | Q8T1C6 |
|---|
| NCBI Gene ID | 8620036 |
|---|
| Source species | Dictyostelium discoideum |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 5 |
|---|
Function and localisation
| Enzyme function | [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase (EC 2.4.1.229) |
|---|
| Subcellular location | Cytoplasm |
|---|
Structure and mechanism
| Fold type | GT-A |
|---|
| Catalytic mechanism | Retaining |
|---|
| Cation dependence | Yes (Mg2+) |
|---|
| Oligomeric state | monomer |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-glucosamine |
|---|
| Donor CCD code(s) | UD1 |
|---|
| Acceptor substrate(s) | trans-4-hydroxy-L-prolyl-[Skp1 protein] |
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
423 aa
MNENSIFVSIISYRDSECQWTIKNLIELAKYKENIFIGVCLQYSMNDDSDNKCFQFNFEEEYGKNQIRIIRMNHTEAKGPCYARALVQQQLFKGEKYYLQIDSHMRFVKDWDIEMINQLLQCKKPNDDNGGMVIDEKAILTCYPMGYKLPNLIPTHRFPILLVASGFGENDGFLRLGGKIVSKKLIEPCSSLFWVSGFSFSRSDIINSVPYDPNLQYLFFGEEISMSARLFTHGYNFYSPTKTLIFHLWNRDYRSTFRENNSLEIQKLEENSKKRLLILFNQNNNNINDNDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSSSSSSNNNNNNNNNNNNSSSTNNNNNNNNNNDDGIKIELKYNLGKIKSLDDYSNYCGVDFKNKTINNKGKFGGYYEERETFFMNEIMEYVIKSQIGI
Catalytic domain sequence
383 aa
SIFVSIISYRDSECQWTIKNLIELAKYKENIFIGVCLQYSMNDDSDNKCFQFNFEEEYGKNQIRIIRMNHTEAKGPCYARALVQQQLFKGEKYYLQIDSHMRFVKDWDIEMINQLLQCKKPNDDNGGMVIDEKAILTCYPMGYKLPNLIPTHRFPILLVASGFGENDGFLRLGGKIVSKKLIEPCSSLFWVSGFSFSRSDIINSVPYDPNLQYLFFGEEISMSARLFTHGYNFYSPTKTLIFHLWNRDYRSTFRENNSLEIQKLEENSKKRLLILFNQNNNNINDNDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSSSSSSNNNNNNNNNNNNSSSTNNNNNNNNNNDDGIKIELKYNLGKIKSLDDYSNYCGVDFK
