Home/GT Families/GT7/B4galnt4
B4galnt4
Mus musculus · N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.244)
GT7Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT7 · CAZy entry |
|---|
| Gene symbol | B4galnt4 |
|---|
| Synonyms / alternate names | - Beta-1
- 4-N-acetylgalactosaminyltransferase IV
|
|---|
| UniProt accession | Q766D5 |
|---|
| NCBI Gene ID | 330671 |
|---|
| Source species | Mus musculus |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 4 |
|---|
Function and localisation
| Enzyme function | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.244) |
|---|
| Subcellular location | - Golgi apparatus
- Golgi stack membrane
|
|---|
Structure and mechanism
| Fold type | GT-A |
|---|
| Catalytic mechanism | Inverting |
|---|
| Cation dependence | Yes (Mn2+) |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-galactosamine |
|---|
| Donor CCD code(s) | UD2 |
|---|
| Acceptor substrate(s) | an N-acetyl-beta-D-glucosaminyl derivative |
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
1034 aa
MPWFPVKKVRKQMKLLLLLLLLTCAAWLTYVHRSLVRPGRALRQRLGYGRDGEKLTGVTDSRGVRVPSSTQRSEDSSESHEEEQAPEGRGPNMLFPGGPRKPPPLNLTHQTPPWREEFKGQVNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVTKLAVSPKWKNYGLRIFGFIHPARDGDIQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDKGSDHVEVGWRAFLPGLKFEIIDSAHISLYTDESSLKMDHVAHVPQSPASHIGGFPPQGEPSADMLHPDPRDTFFLTPRMEPLSLENVLEPCAYAPTYILKDFPIARYQGLQFVYLSFIYPNDHTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGEEDEEEEVQRRAFLFLNPDDFLDEEDEQDLLDSLEPTDASVQQSHRTPTPAASTGTTASPTPPTTSPLDEQTLRHSRALNWAPRPLPLFLGRAPPPRTVEKSPSKVYVTRVRPGQRASPRALRDSPWPPFPGVFLRPKPLPRVQLRVPPHPPRTQGYRTSGPKVTELKPPVRAQTSQGGREGQLHGQGLMVPTVDLNSSVETQPVTSFLSLSQVSRPQLPGEGEEGEEDGAPGDEATSEDSEEEEEPAAGRPLGRWREDAINWQRTFSVGAMDFELLRSDWNDLRCNVSGNLQLPEAEAVDVVAQYMERLNAKHGGRFSLLRIVNVEKRRDSARGSRFLLELELQERGGSRQRLSEYVFLRLPGARVGDEDGESPEPPPAASIHPDSRPELCRPLHLAWRQDVMVHFIVPVKNQARWVVQFLADMTALHVHTGDSYFNIILVDFESEDMDVERALRAAQLPRYQYLKRTGNFERSAGLQTGVDAVEDPSSIVFLCDLHIHFPPNILDSIRKHCVEGKLAFAPVVMRLGCGSSPWDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRHFYHHYHSKRGMWATRSRKGARAQRS
Catalytic domain sequence
307 aa
AEAVDVVAQYMERLNAKHGGRFSLLRIVNVEKRRDSARGSRFLLELELQERGGSRQRLSEYVFLRLPGARVGDEDGESPEPPPAASIHPDSRPELCRPLHLAWRQDVMVHFIVPVKNQARWVVQFLADMTALHVHTGDSYFNIILVDFESEDMDVERALRAAQLPRYQYLKRTGNFERSAGLQTGVDAVEDPSSIVFLCDLHIHFPPNILDSIRKHCVEGKLAFAPVVMRLGCGSSPWDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRHFYHHYHSK
