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B4galt7
Mus musculus · Beta-1,4-galactosyltransferase 7 (EC 2.4.1.-; 2.4.1.133)
GT7Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT7 · CAZy entry |
| Gene symbol | B4galt7 |
| Synonyms / alternate names | - Xgalt1
- Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I
- UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7
- UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7
- UDP-galactose:beta-xylose beta-1,4-galactosyltransferase
- XGPT
- XGalT-1
- Xylosylprotein 4-beta-galactosyltransferase
- Xylosylprotein beta-1,4-galactosyltransferase
|
| UniProt accession | Q8R087 |
| NCBI Gene ID | 218271 |
| Source species | Mus musculus |
| Taxonomic domain | Eukaryota |
| UniProt annotation level | 5 |
Function and localisation
| Enzyme function | Beta-1,4-galactosyltransferase 7 (EC 2.4.1.-; 2.4.1.133) |
| Subcellular location | - Golgi apparatus
- Golgi stack membrane
|
Structure and mechanism
| Fold type | GT-A |
| Catalytic mechanism | Inverting |
| Cation dependence | Yes (Mn2+) |
| Oligomeric state | not curated |
| PDB structures | not curated |
Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-galactose |
| Donor CCD code(s) | GDU |
| Acceptor substrate(s) | 3-O-(beta-D-xylosyl)-L-seryl-[protein] |
| Acceptor CCD / GlycoCT | not curated |
Protein sequences
Full protein sequence
327 aa
MLPSRRKAAQLPWEDGRARLLPGGLRRKCSIFHLFIAFLLLVFFSLLWLQLSCSGDMAQVTRGQGQETSGPPRACPPEPPPEHWEEDESWGPHRLAVLVPFRERFEELLVFVPHMHRFLSRKRIQHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEAGPFHVASPELHPLYHYKTYVGGILLLSKQHYQLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTGYQTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYRVDSRTALSIGGAPCTVLNVMLDCDKTATPWCIFG
Catalytic domain sequence
224 aa
PHRLAVLVPFRERFEELLVFVPHMHRFLSRKRIQHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEAGPFHVASPELHPLYHYKTYVGGILLLSKQHYQLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTGYQTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYRVDSRTALSIGGAPCTVLNVMLD