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sqv-3
Caenorhabditis elegans · Xylosylprotein 4-beta-galactosyltransferase (EC 2.4.1.133)
GT7Model organism · annotation ≥ 4Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT7 · CAZy entry |
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| Gene symbol | sqv-3 |
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| Synonyms / alternate names | - Squashed vulva protein 3
- UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase sqv-3
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| UniProt accession | P34548 |
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| NCBI Gene ID | 176382 |
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| Source species | Caenorhabditis elegans |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Xylosylprotein 4-beta-galactosyltransferase (EC 2.4.1.133) |
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| Subcellular location | Membrane |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | Yes (Mn2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-galactose |
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| Donor CCD code(s) | GDU |
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| Acceptor substrate(s) | 3-O-(beta-D-xylosyl)-L-seryl-[protein] |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
289 aa
MKLKTRLILSGTILISLAACYFLVLLVLDLEITRDLMTDYVDPRPLQTSYHKLCVIVPYRDRLEELREFSPHMSKFLHNQNVSHHILIINQTDPLRFNRASLINVGWNEADRLGCDYMVMNDVDLLPVNPEVPYDFPGIGVIRHITSPQYHPKYHYEKFIGGILMLTLKDYKKLNGMSNKYWGWGLEDDEFYLRIIDSKLNLTRVSGLSTDSSNTFRHIHGPKRKRDYTPKKNDKNQWEIKRKRDHVSGLHDVRYLIDSRQLLDFSGTSVTIINVALHCDLNWTPYCKS
Catalytic domain sequence
229 aa
YHKLCVIVPYRDRLEELREFSPHMSKFLHNQNVSHHILIINQTDPLRFNRASLINVGWNEADRLGCDYMVMNDVDLLPVNPEVPYDFPGIGVIRHITSPQYHPKYHYEKFIGGILMLTLKDYKKLNGMSNKYWGWGLEDDEFYLRIIDSKLNLTRVSGLSTDSSNTFRHIHGPKRKRDYTPKKNDKNQWEIKRKRDHVSGLHDVRYLIDSRQLLDFSGTSVTIINVALH
