Home/GT Families/GT73/waaZ
waaZ
Escherichia coli (strain K12) · Probable 3-deoxy-manno-octulosonic acid transferase (EC 2.4.99.15)
GT73Model organism · annotation ≥ 4Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT73 · CAZy entry |
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| Gene symbol | waaZ |
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| Synonyms / alternate names | - rfaZ
- Lipopolysaccharide core biosynthesis protein WaaZ
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| UniProt accession | P27241 |
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| NCBI Gene ID | 948146 |
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| Source species | Escherichia coli (strain K12) |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Probable 3-deoxy-manno-octulosonic acid transferase (EC 2.4.99.15) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | CMP-3-deoxy-beta-D-manno-octulosonate |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | - an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA
- alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
283 aa
MKNIRYIDKKDVENLIENKISDDVIIFLSGPTSQKTPLSVLRTKDIIAVNGSAQYLLSNNIVPFIYVLTDVRFLHQRRDDFYKFSQRSRYTIVNVDVYEHASKEDKLYILQNCLVLRSFYRREKGGFIKKIKFNILRQIHKELLISVPLSKKGRLVGFCKDISLGYCSCHTIAFAAIQIAYSLKYARIICSGLDLTGSCSRFYDENKNPMPSELSRDLFKILPFFRFMHDNVKDINIYNLSDDTAISYDVIPFIKLQDISAEESKDMTRKKMQYRTSTDSYAN
Catalytic domain sequence
250 aa
YIDKKDVENLIENKISDDVIIFLSGPTSQKTPLSVLRTKDIIAVNGSAQYLLSNNIVPFIYVLTDVRFLHQRRDDFYKFSQRSRYTIVNVDVYEHASKEDKLYILQNCLVLRSFYRREKGGFIKKIKFNILRQIHKELLISVPLSKKGRLVGFCKDISLGYCSCHTIAFAAIQIAYSLKYARIICSGLDLTGSCSRFYDENKNPMPSELSRDLFKILPFFRFMHDNVKDINIYNLSDDTAISYDVIPFIK
