Home/GT Families/GT76/Pigv
Pigv
Mus musculus · GPI alpha-1,6-mannosyltransferase 2 (EC 2.4.1.-)
GT76Non-model organism · annotation 4–5Fold GT-CInverting
External resources
Identification and annotation
| CAZy family | GT76 · CAZy entry |
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| Gene symbol | Pigv |
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| Synonyms / alternate names | - GPI mannosyltransferase II
- Phosphatidylinositol-glycan biosynthesis class V protein
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| UniProt accession | Q7TPN3 |
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| NCBI Gene ID | 230801 |
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| Source species | Mus musculus |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | GPI alpha-1,6-mannosyltransferase 2 (EC 2.4.1.-) |
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| Subcellular location | Endoplasmic reticulum membrane |
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Structure and mechanism
| Fold type | GT-C |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | - a 2-acyl-6-(alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol
- a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate
- a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
493 aa
MGLLDPSQKEVLRFAVNCRILTLVLQALFNLIIPDHHADAFCPPRLAPSGSADQLVEGLLGGLSRWDAEHFLFIAEHGYLYEHNFAFFPGFPLALLMGTELLRPLQGLLSQRSCLLVSVALLNLLFSVLAAVALHDLGCLVLHCPRQALCAALLFCISPANVFLAAGYSEALFAFLTFSAMGQLERGRGWASGLLFALAAGVRSNGLVSLGFLLHSQCRGFCSSLAVLSPWKPLVKLMASVCLSVLIVSLPFALFQYRAYIQFCSPGSAPSIPEPLLQLAADKGYRLAGENAPPWCSWDLPLIYNYIQDVYWNVGLLRYYELKQVPNFLLATPVTVLVVWATWTYVTTHPWLCLTLGLQRTKDRENPEKPHRGFLSPKVFVYLVHAAALLVFGGLCMHVQVLTRFLASSTPIMYWFPAHLLQDQEPLLRCVDTEPGKLPQEKSPPGQKAPRNCLMKLFYDWKRCSPVTRCVLVYFLTYWLLGLILHCNFLPWT
Catalytic domain sequence
485 aa
KEVLRFAVNCRILTLVLQALFNLIIPDHHADAFCPPRLAPSGSADQLVEGLLGGLSRWDAEHFLFIAEHGYLYEHNFAFFPGFPLALLMGTELLRPLQGLLSQRSCLLVSVALLNLLFSVLAAVALHDLGCLVLHCPRQALCAALLFCISPANVFLAAGYSEALFAFLTFSAMGQLERGRGWASGLLFALAAGVRSNGLVSLGFLLHSQCRGFCSSLAVLSPWKPLVKLMASVCLSVLIVSLPFALFQYRAYIQFCSPGSAPSIPEPLLQLAADKGYRLAGENAPPWCSWDLPLIYNYIQDVYWNVGLLRYYELKQVPNFLLATPVTVLVVWATWTYVTTHPWLCLTLGLQRTKDRENPEKPHRGFLSPKVFVYLVHAAALLVFGGLCMHVQVLTRFLASSTPIMYWFPAHLLQDQEPLLRCVDTEPGKLPQEKSPPGQKAPRNCLMKLFYDWKRCSPVTRCVLVYFLTYWLLGLILHCNFLPWT
