Home/GT Families/GT77/agtA
agtA
Dictyostelium discoideum · UDP-galactose:fucoside alpha-3-galactosyltransferase (EC 2.4.1.37)
GT77Model organism · annotation ≥ 4Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT77 · CAZy entry |
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| Gene symbol | agtA |
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| Synonyms / alternate names | - GT78
- Alpha-GalT1
- Fucosylgalactoside 3-alpha-galactosyltransferase
- Skp1 alpha-3-galactosyltransferase
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| UniProt accession | Q54RP0 |
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| NCBI Gene ID | 8623882 |
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| Source species | Dictyostelium discoideum |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | UDP-galactose:fucoside alpha-3-galactosyltransferase (EC 2.4.1.37) |
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| Subcellular location | Cytoplasm |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Retaining |
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| Cation dependence | Yes (Mn2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-galactose |
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| Donor CCD code(s) | GDU |
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| Acceptor substrate(s) | an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
648 aa
MEKKVEYIKENDKIVLMCNYGFRDMTLNLLKCFEKLSIDKSRYILYCMDDKAYQFFAEFKGIECQRFSRDDIINSSTSSTQLFHDNNTNDNKGIYSENAESYGDIGFRAICNEKPLVVLDVLKKGYNVLWTDTDIVWKRDPFIHFYQDINQENQFTNDDDIDLYVQQDDDDICAGFYFIRSNQRTIKFIQDSINFLNPCIDDQIAMRLFLKSQGINIKSKNILLSLSENDKKDKIRYRLLDKKLFPNGTNYFNLKITQRDNITPFIIHNNCIIGHRSKKDRFIEYGLWYINDDEIDINSNINNDDENNKEIKLFKNVLKNHTDIITSINSSDDGKLFTTSIDKSIKIWKFENTSGNDTDNGIFKVLKSKYIHKRGGIWSTFIFSSNNNNNNDYGFENLLTSSHDKTIQYWDNNLQVIQTFIGHTGIINQLIVIPNSSYFFTCSDDNTIRQFDLNNINFKRVFIGHNGWVSSIAINKNLNTLYSCSNDGTIRFWDINSGRCLNIIKGNQGGWIRKIIYNDNLNQLISGGNDGTIKIWSCDNLNNFNDNQYLLKINTNENSSINDLQFDSDTNLIYCAFENGSLKSFKLTSNNNNNNNNNNNNNNNTINYSLDKVYQGHLNSSINCIHISKSLNLLFSGGFDKQIKSWDL
Catalytic domain sequence
242 aa
SRYILYCMDDKAYQFFAEFKGIECQRFSRDDIINSSTSSTQLFHDNNTNDNKGIYSENAESYGDIGFRAICNEKPLVVLDVLKKGYNVLWTDTDIVWKRDPFIHFYQDINQENQFTNDDDIDLYVQQDDDDICAGFYFIRSNQRTIKFIQDSINFLNPCIDDQIAMRLFLKSQGINIKSKNILLSLSENDKKDKIRYRLLDKKLFPNGTNYFNLKITQRDNITPFIIHNNCIIGHRSKKDRF
