Home/GT Families/GT_NC/TRUGW13939_11895
TRUGW13939_11895
Talaromyces rugulosus · sterol 14alpha-demethylase (EC 1.14.14.154)
GT_NCNon-model organism · annotation 4–5Fold n/a (non-classified)
External resources
Identification and annotation
| CAZy family | GT_NC |
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| Gene symbol | TRUGW13939_11895 |
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| Synonyms / alternate names | not curated |
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| UniProt accession | A0A7H8RE03 |
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| NCBI Gene ID | 55999371 |
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| Source species | Talaromyces rugulosus |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | sterol 14alpha-demethylase (EC 1.14.14.154) |
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| Subcellular location | Membrane |
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Structure and mechanism
| Fold type | n/a (non-classified) |
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| Catalytic mechanism | not curated |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | - 32-hydroxyeburicol
- reduced [NADPH--hemoprotein reductase]
- O2
- 32-hydroxylanosterol
- 32-oxoeburicol
- 32-oxolanosterol
- a 14alpha-formyl steroid
- a 14alpha-hydroxymethyl steroid
- a 14alpha-methyl steroid
- 3 reduced [NADPH--hemoprotein reductase]
- 3 O2
- eburicol
- lanosterol
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
935 aa
MEALLFHSRAPFPIASVLVSLLLCILLATAVNIFSQLWKQHDTSKPPVVFHYFPVIGSTITYGKDPLTFFAECKAKYGDVFTFILLGRSVTVYLGASGNNFVLNGRQSELSAEEVYSPLTTPVFGTDVIFDCDNAKFMQQKKFVKFGLSQAALQSYVQLIAQETASFFDTYTPLQTGKGNNNTGILDVPSAMAELTIYTASSSLQGAEVRRQFSSAGSRIADLYHDLDMGFSPINFFLPSWVPLPRNRKRDAAQREMTRIYTDIIAQRRLESNAANTAKDTDAQDMIWNLTNNCTYKDGSKLPDKEIAHMMIALLLGGHHSSSAVIAFALLSLASRPDIQQELYDEQVRELGPGDLSYDGLQRLKLHAHVIKETLRLYNPIHSIMRLAKKPLVVTGNSGVVIPSGHTLLASPAFSARDESYFADPLKWDPHRWEKSSAHDTTDDDDDESSGKGSNNPYLPFGGGRHRCIGERFAYIQLGVILALFVRTFHIKSVRGKAGELLTTDYTSLFSRPLTPATVAWERRGRPIDPMPWIRGYLRRYAFFHTLLIAACIFLPWWIRRPDEGVQFAALRRIECTSLPQSEDVFVVMKTGSTVLRDRLPIHFETTFKCIPDYIIFSDAAESFRGHIVNDALSYIDESIKSKFPSDFQLHDHIRDKGGSALSTNQGWRLDKYKFLPMIKGALDARPNARWFVFIEDDTAIVWSNLLRWLASHDYRQPYFFGREEKVADRPFAHGGSGYVLSNAALRHAVNYMEPRMQEYFNLTNEIIYGDISLGWMLSDSGIPLTNVWPLFQGEPPDRIQYAEDIWCQPVLTQHHMSSQAIASLWMLEQANLLHAQSADLLHRDVFNALIRPTLSHRLENWDNGRGYEQACGTVSECETLCMADETCVQFRYASGQCRLSSRVRLGVPTASKFGITSGWLVQRIDRVYGGLQCH
Catalytic domain sequence
not curated
