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ALG13
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) · UDP-N-acetylglucosamine transferase subunit ALG13 (EC 2.4.1.141)
GT1Model organism · annotation ≥ 4Fold GT-BInverting2 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT1 · CAZy entry |
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| Gene symbol | ALG13 |
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| Synonyms / alternate names | Asparagine-linked glycosylation protein 13 |
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| UniProt accession | P53178 |
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| NCBI Gene ID | 852835 |
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| Source species | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | UDP-N-acetylglucosamine transferase subunit ALG13 (EC 2.4.1.141) |
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| Subcellular location | Endoplasmic reticulum |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | heterodimer |
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| PDB structures | 2JZC, 2KS6 |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-glucosamine |
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| Donor CCD code(s) | UD1 |
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| Acceptor substrate(s) | - an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans
- poly-cis-dolichol
|
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
202 aa
MGIIEEKALFVTCGATVPFPKLVSCVLSDEFCQELIQYGFVRLIIQFGRNYSSEFEHLVQERGGQRESQKIPIDQFGCGDTARQYVLMNGKLKVIGFDFSTKMQSIIRDYSDLVISHAGTGSILDSLRLNKPLIVCVNDSLMDNHQQQIADKFVELGYVWSCAPTETGLIAGLRASQTEKLKPFPVSHNPSFERLLVETIYS
Catalytic domain sequence
74 aa
KVIGFDFSTKMQSIIRDYSDLVISHAGTGSILDSLRLNKPLIVCVNDSLMDNHQQQIADKFVELGYVWSCAPTE
