Home/GT Families/GT1/atg26
atg26
Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) · Sterol 3-beta-glucosyltransferase (EC 2.4.1.-; 2.4.1.173)
GT1Non-model organism · annotation 4–5Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT1 · CAZy entry |
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| Gene symbol | atg26 |
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| Synonyms / alternate names | Autophagy-related protein 26 |
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| UniProt accession | A2QNQ5 |
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| NCBI Gene ID | not curated |
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| Source species | Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Sterol 3-beta-glucosyltransferase (EC 2.4.1.-; 2.4.1.173) |
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| Subcellular location | - Cytoplasm
- Preautophagosomal structure membrane
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-glucose |
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| Donor CCD code(s) | UPG |
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| Acceptor substrate(s) | |
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| Acceptor CCD / GlycoCT | ergosterol |
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Protein sequences
Full protein sequence
1371 aa
MRPFIDDAKRRVDRRLSASRQSISNSRMFASVLPERLRNDNDDDDDSQVDFSAPPGGMGPREGHMQYMHQSIFGMIAAVGSRSGFHARYDESSDSDGEDESRARKDAENLSATAGALPKRSGNESPRLSPKPQSPTPERGRRHRRTISDHKLLRPFKLNSKQNKGQEPAVQSEPQTGDEMSRASTPKRPRSVTPRAAPVLSRMVEARALLDTEDSTKGAPSTTEEIRDEGPTQKSASALSLRLKEMFGFEAPEKVLVEYACSFLQSMLLQGYMYVTEGHVCFYAYLPRKSTVAIKSGYVYKRGRKNPKYNRYWFSLKGDVLSYYADPSKLYFPSGHVDLRYGISASLAEPKDKGREVKDFQVTTDQRTYYFRADSSSSAKEWVKALQKVIFRTHNDKGSVKISFPIENIIDIEESPMVDFAETFKIRVVESEETYAIDEYYFTSFNYGQDAFNFLKGLVADTPMKRSQQTLSPQPEQTSRSRRTRGSQNRWSITSATSQSRGIGKSGNRRRSASTGQFSFGHDALSMSPPMRQQDSSLSFGNSFEQATEASGILQSMTDTTESASQILNRSDVFQSPTIRTMRRGPSGAEKTVRRHSDETARSVHTTRNGPEIQYAVSESDRDTQTPSGLHPSTPALNELVRAGVYPLQRAAGFAEYLKTRSKQMSNLLASESMGYLEKVSGMWAGGGKHYGESENILPDDQAVDPEDLEAGCKDGDRFREHFALPPSEKLQASYFAWLHRMIPLYGKIYISQKKLCFRSLMPGTRTKMILPLKDVENVDKEKGFNFGRHGLVVVIRGHEELFFEFGTADTRDDCAVTLHKGLESTKFLMASGLLAECEEKDESESATAEHRLLQEARLDITGMHSSRSAMAASNELHPIFDDPRASIINFKPTESLRITCLTIGSRGDVQPYIALCKGLLAEGHRPKIATHAEFEPWVRKHGIDFALVDGDPAELMRICVENGMFTYSFFKEATAKFRGWIDDLLSSAWKACQDTDLLIESPSAMAGIHIAEALRIPYFRAFTMPWSRTRAYPHAFAVPEHKMGGAYNYITYVMFDNVFWKSVAGQVNRWRKKELGLKATGLDKMQPNKVPFLYNYSPTVVPPPLDYPDWIRITGYWFLSEGSDWTPPAELVDFIQRARKDEKKVVYIGFGSIVVSDPSALTRTVIESVQKADVRCILSKGWSDRLGDPASAKSEVPLPPEIYQIQSAPHDWLFSHIDAAAHHGGAGTTGASLRAGVPTIVKPFFGDQFFFGTRVEDLGVGICLKKLNVTMFSRALWEATHDERMIVKAHKLGAQIRSEDGVDTAIQAIYRDLEYAKTLAQARSNVSSTPFSPTPSAKTVAEQEADEDVPEEEWTIVEDDTELEMRPTVA
Catalytic domain sequence
414 aa
LRITCLTIGSRGDVQPYIALCKGLLAEGHRPKIATHAEFEPWVRKHGIDFALVDGDPAELMRICVENGMFTYSFFKEATAKFRGWIDDLLSSAWKACQDTDLLIESPSAMAGIHIAEALRIPYFRAFTMPWSRTRAYPHAFAVPEHKMGGAYNYITYVMFDNVFWKSVAGQVNRWRKKELGLKATGLDKMQPNKVPFLYNYSPTVVPPPLDYPDWIRITGYWFLSEGSDWTPPAELVDFIQRARKDEKKVVYIGFGSIVVSDPSALTRTVIESVQKADVRCILSKGWSDRLGDPASAKSEVPLPPEIYQIQSAPHDWLFSHIDAAAHHGGAGTTGASLRAGVPTIVKPFFGDQFFFGTRVEDLGVGICLKKLNVTMFSRALWEATHDERMIVKAHKLGAQIRSEDGVDTAIQAI
