Home/GT Families/GT1/gtfD
gtfD
Amycolatopsis orientalis · Devancosaminyl-vancomycin vancosaminetransferase (EC 2.4.1.322)
GT1Non-model organism · annotation 4–5Fold GT-BInverting1 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT1 · CAZy entry |
|---|
| Gene symbol | gtfD |
|---|
| Synonyms / alternate names | - Devancosamine-vancomycin TDP-vancosaminyltransferase
- Glycosyltransferase GtfD
|
|---|
| UniProt accession | Q9AFC7 |
|---|
| NCBI Gene ID | not curated |
|---|
| Source species | Amycolatopsis orientalis |
|---|
| Taxonomic domain | Bacteria |
|---|
| UniProt annotation level | 4 |
|---|
Function and localisation
| Enzyme function | Devancosaminyl-vancomycin vancosaminetransferase (EC 2.4.1.322) |
|---|
| Subcellular location | not curated |
|---|
Structure and mechanism
| Fold type | GT-B |
|---|
| Catalytic mechanism | Inverting |
|---|
| Cation dependence | No |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | 1RRV |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | dTDP-beta-L-vancosamine |
|---|
| Donor CCD code(s) | not curated |
|---|
| Acceptor substrate(s) | devancoaminyl-vancomycin |
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
408 aa
MRVLLSVCGTRGDVEIGVALADRLKALGVQTRMCAPPAAEERLAEVGVPHVPVGLPQHMMLQEGMPPPPPEEEQRLAAMTVEMQFDAVPGAAEGCAAVVAVGDLAAATGVRSVAEKLGLPFFYSVPSPVYLASPHLPPAYDEPTTPGVTDIRVLWEERAARFADRYGPTLNRRRAEIGLPPVEDVFGYGHGERPCWPADPVLAPLQPDVDAVQTGAWLLSDERPLPPELEAFLAAGSPPVHIGFGSSSGRGIADAAKVAVEAIRAQGRRVILSRGWTELVLPDDRDDCFAIDEVNFQALFRRVAAVIHHGSAGTEHVATRAGVPQLVIPRNTDQPYFAGRVAALGIGVAHDGPTPTFESLSAALTTVLAPETRARAEAVAGMVLTDGAAAAADLVLAAVGREKPAVPA
Catalytic domain sequence
384 aa
MRVLLSVCGTRGDVEIGVALADRLKALGVQTRMCAPPAAEERLAEVGVPHVPVGLPQHMMLQEGMPPPPPEEEQRLAAMTVEMQFDAVPGAAEGCAAVVAVGDLAAATGVRSVAEKLGLPFFYSVPSPVYLASPHLPPAYDEPTTPGVTDIRVLWEERAARFADRYGPTLNRRRAEIGLPPVEDVFGYGHGERPCWPADPVLAPLQPDVDAVQTGAWLLSDERPLPPELEAFLAAGSPPVHIGFGSSSGRGIADAAKVAVEAIRAQGRRVILSRGWTELVLPDDRDDCFAIDEVNFQALFRRVAAVIHHGSAGTEHVATRAGVPQLVIPRNTDQPYFAGRVAALGIGVAHDGPTPTFESLSAALTTVLAPETRARAEAVAGMVL
