Home/GT Families/GT110/Rxylt1
Rxylt1
Mus musculus · Ribitol-5-phosphate xylosyltransferase 1 (EC 2.4.2.61)
GT110Non-model organism · annotation 4–5Fold GT-Aunknown
External resources
Identification and annotation
| CAZy family | GT110 · CAZy entry |
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| Gene symbol | Rxylt1 |
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| Synonyms / alternate names | - Tmem5
- Transmembrane protein 5
- UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase
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| UniProt accession | Q8VDX6 |
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| NCBI Gene ID | 216395 |
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| Source species | Mus musculus |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Ribitol-5-phosphate xylosyltransferase 1 (EC 2.4.2.61) |
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| Subcellular location | Golgi apparatus membrane |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | unknown |
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| Cation dependence | No |
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| Oligomeric state | Forms a complex composed of FKTN/fukutin, FKRP and RXYLT1/TM |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-xylose |
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| Donor CCD code(s) | UDX |
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| Acceptor substrate(s) | 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
444 aa
MRLTRTRLCSLLVALYCLFSIYAAYHVFFGRRRRPLGTTSRNSRKAAAAQAKERRGREQSALESEEWNPWEGDEKNEQRHRVKTNLQILNKSTKEKIEHRVQIWGKAAIGLYLWEHIFEGTLDPADVTAQWREGQSVVGRTHYSFITGPAVVPGYFSIDVDNVVLVLNGREKAKIFHATQWLIYAQNLMKTQKLQHLAVVLLGNEHCENDWIMQFLKRNGGFVDLLFITYDSPWINGADILQWPLGVATYRQFPVVEASWTMLHDERPYICNFLGTAYENSSRQALMNILKQDGNDKLCWVSAREQWQPQETNESLKNYQDALLHSDLTLCPVGVNTECYRIYEACSFGSIPVVEDVMTAGHCGNTTSQHSAPLQLLKAMGAPFIFIKNWKELPAILEKEKTISLQEKIQRRKVLLHWYQHFKTELKWKFTKILESSFFINNKV
Catalytic domain sequence
338 aa
VQIWGKAAIGLYLWEHIFEGTLDPADVTAQWREGQSVVGRTHYSFITGPAVVPGYFSIDVDNVVLVLNGREKAKIFHATQWLIYAQNLMKTQKLQHLAVVLLGNEHCENDWIMQFLKRNGGFVDLLFITYDSPWINGADILQWPLGVATYRQFPVVEASWTMLHDERPYICNFLGTAYENSSRQALMNILKQDGNDKLCWVSAREQWQPQETNESLKNYQDALLHSDLTLCPVGVNTECYRIYEACSFGSIPVVEDVMTAGHCGNTTSQHSAPLQLLKAMGAPFIFIKNWKELPAILEKEKTISLQEKIQRRKVLLHWYQHFKTELKWKFTKILESSF
