Home/GT Families/GT2/CHS3
CHS3
Exophiala dermatitidis · Chitin synthase 3 (EC 2.4.1.16)
GT2Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT2 · CAZy entry |
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| Gene symbol | CHS3 |
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| Synonyms / alternate names | - Chitin-UDP acetyl-glucosaminyl transferase 3
- Class-III chitin synthase 3
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| UniProt accession | P30602 |
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| NCBI Gene ID | not curated |
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| Source species | Exophiala dermatitidis |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Chitin synthase 3 (EC 2.4.1.16) |
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| Subcellular location | Cell membrane |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-glucosamine |
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| Donor CCD code(s) | UD1 |
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| Acceptor substrate(s) | [(1->4)-N-acetyl-beta-D-glucosaminyl](n) |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
885 aa
MASQYPGHQLDDIPSTNVYRPPPRHEDDEAEHALLHQNSAYQSQYDDPHSRPLTPGQESVYTLNESYVGGDPSKVPVTSYNPQYTQPYGQGYGMNNSRPGFPTPGPPDPIDRTDSTEAWRERQAPGFGTIKRYATRKVKLVQGSVLSIDYPVPSAIQNAIQAKYRNDLEGGSEEFTHMRYTAATCDPDDFTLKNGYNLRPAMYNRHTELLIAITYYNEDKVLTARTLHGVMQNIRDIVNLKKSEFWNKGGPAWQKIVVCLVFDGIDPCDKNTLDVLATIGVYQDGVMKKDVDGKETVAHIFEYTTQLSVTANQQLIRPNDNDATSLPPAQMIFCLKQKNRKKINSHRWLFNAFGRILNPEVCILLDAGTKPGSKSLMALWQAFYNDKDLGGACGEIHAMLGPGGVFGRKLLNPLVAAQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMGRPLEQYFHGDHTLSKTLGKKGIEGMNIFKKNMFLAEDRILCFELVAKAGSKWHLSYVKASKAETDVPEGPPEFIGQRRRWLNGSFAASMYCLMHFSRMYKSGHNLIRMFFLHIQMIYNIVSVLLSWFSLASFWLTTKVLMDLVGQPSTSNDNAAFPFGNTATPIINTILQYLYLAFLLLQFILALGNRPKGSKVAYIISFCLFGLIQLYVIVLSMYLVVRAFTTKNGTDIVTNEGANEFVKSFFASTGPGIVIIALAATFGLYFVASFLYMDPWHMFTSFAQYLLLMPSFINILMIYAFSNWHDVSWGTKGSDKADVLPSAQTKKDEKSKTAVVEEVDKPQADIDSQFEATVRRALAPYKPPEEKEEKTLEDSYKNFRTRLVATWIFSNALLAVAITSDSLDRFGFTSEPLRGPAISSRRFCGLLRPCL
Catalytic domain sequence
343 aa
LLIAITYYNEDKVLTARTLHGVMQNIRDIVNLKKSEFWNKGGPAWQKIVVCLVFDGIDPCDKNTLDVLATIGVYQDGVMKKDVDGKETVAHIFEYTTQLSVTANQQLIRPNDNDATSLPPAQMIFCLKQKNRKKINSHRWLFNAFGRILNPEVCILLDAGTKPGSKSLMALWQAFYNDKDLGGACGEIHAMLGPGGVFGRKLLNPLVAAQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMGRPLEQYFHGDHTLSKTLGKKGIEGMNIFKKNMFLAEDRILCFELVAKAGSKWHLSYVKASKAETDVPEGPPEFIGQRRRWLNGSFAASMYCLMHF
