Home/GT Families/GT2/DPM1
DPM1
Mycosarcoma maydis · Dolichol-phosphate mannosyltransferase (EC 2.4.1.83)
GT2Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT2 · CAZy entry |
|---|
| Gene symbol | DPM1 |
|---|
| Synonyms / alternate names | - Dolichol-phosphate mannose synthase
- Dolichyl-phosphate beta-D-mannosyltransferase
- Mannose-P-dolichol synthase
|
|---|
| UniProt accession | P54856 |
|---|
| NCBI Gene ID | 23565949 |
|---|
| Source species | Mycosarcoma maydis |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 4 |
|---|
Function and localisation
| Enzyme function | Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) |
|---|
| Subcellular location | Endoplasmic reticulum membrane |
|---|
Structure and mechanism
| Fold type | GT-A |
|---|
| Catalytic mechanism | Inverting |
|---|
| Cation dependence | Yes (Mg2+, Mn2+, Ca2+) |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | GDP-alpha-D-mannose |
|---|
| Donor CCD code(s) | GDD |
|---|
| Acceptor substrate(s) | - a di-trans
- poly-cis-dolichyl phosphate
|
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
294 aa
MSIALDMDASAKMRKQPGSSGWSTSSTPSCSVIVPAFRENLNLRPLVTRLSSAFASQSSSELANTEIIIVDDNSRDGSVETVSALQSEGYNVRIIVRTSERGLSSAVVRGFREARGQRMICMDADLQHPPEAVPSLLLALNGQKSFVLGTRYGVGVSMDKDWPLHRRIISSGARMLARPLTSASDPMSGFFGITKHSFHTADHHINAQGFKIALDLLVKSGVHSTDIAEVPFSFGLRQEGESKLDGKVMFKYLQQLVELYRFRFGTVPIVFVLIVLLVLALYIWSHVLAPMLGA
Catalytic domain sequence
165 aa
SVIVPAFRENLNLRPLVTRLSSAFASQSSSELANTEIIIVDDNSRDGSVETVSALQSEGYNVRIIVRTSERGLSSAVVRGFREARGQRMICMDADLQHPPEAVPSLLLALNGQKSFVLGTRYGVGVSMDKDWPLHRRIISSGARMLARPLTSASDPMSGFFGITK
