Home/GT Families/GT2/MPIPNATIZW_LOCUS15637
MPIPNATIZW_LOCUS15637
Pipistrellus nathusii · Activity-dependent neuroprotector homeobox protein (EC 2.4.1.83)
GT2Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT2 · CAZy entry |
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| Gene symbol | MPIPNATIZW_LOCUS15637 |
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| Synonyms / alternate names | - Activity-dependent neuroprotective protein
- Dolichol-phosphate mannose synthase subunit 1
- Dolichol-phosphate mannosyltransferase subunit 1
- Dolichyl-phosphate beta-D-mannosyltransferase subunit 1
- Mannose-P-dolichol synthase subunit 1
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| UniProt accession | A0ABP0AA04 |
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| NCBI Gene ID | not curated |
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| Source species | Pipistrellus nathusii |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Activity-dependent neuroprotector homeobox protein (EC 2.4.1.83) |
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| Subcellular location | - Chromosome
- Endoplasmic reticulum
- Nucleus
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | Yes (Ca2+, Mg2+, Mn2+) |
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| Oligomeric state | Interacts (via N-terminal region) with beta-catenin/CTNNB1 ( |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | not curated |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
1454 aa
MASKTANRTPPRSRRDPEGRVPGRDKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTREVAEQLEKIYGSDKILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKLISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVRARQLNYTIGELRSERSAAAAVRLPEPVKRRLPHPPSPPSAPPLSAPLDDAAARAGTGGSRSRHRRRPPARPPLCCARRAPRQQPRPRREPEPAEATEPGRALAATAVPPPPARRCSRPAPEHAGPARASRPSQETMFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNASTPSSSLSTFKDKSKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEVVRKHIYREHFQHVAAPYIAKSGEKSLNGAVPLSPNAWEEGSIHCKRCLFIPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQEKKGMGLQSRIGSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSNVHLQQNNYGVKSVGQGYGVGQSMRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSFGLGAEQRSQAPARYSLQSANASSVSTGQLKSPSLSQSQASRVLGQSSSKPTAAAAGPPVANTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPFCRSTFNDVEKMAAHMRMVHIDEELGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQSNPPIPPKPQPKLPEKADTPVRSSPQAAVPYKKDIGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPGLAPVKRTYEQIEFPLTKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEDRKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKVHLGKEDDNSSDSFENLEEESNGSGSPFDPVFEVEPKIPNDTPEEHIQKVISEDALESEEKLDQKGVDGSKYETIHLTEEPNKLMHDASDSEVDQDDVVEWKGGASPSESGPGSQHVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSGPQIEWQNSTIDSEDGEQFENMTDGVAEPMHGSLTGVKLSSQQA
Catalytic domain sequence
171 aa
SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTREVAEQLEKIYGSDKILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKLISRGANFITQILLRPGASDLTGSFRLYRKEVLQKL
