Home/GT Families/GT2/csmA
csmA
Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) · Chitin synthase csmA (EC 2.4.1.16)
GT2Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT2 · CAZy entry |
|---|
| Gene symbol | csmA |
|---|
| Synonyms / alternate names | - Chitin-UDP acetyl-glucosaminyl transferase csmA
- Class-V chitin synthase csmA
|
|---|
| UniProt accession | A2QC57 |
|---|
| NCBI Gene ID | not curated |
|---|
| Source species | Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 5 |
|---|
Function and localisation
| Enzyme function | Chitin synthase csmA (EC 2.4.1.16) |
|---|
| Subcellular location | - Cell membrane
- Cell septum
- Cell tip
|
|---|
Structure and mechanism
| Fold type | GT-A |
|---|
| Catalytic mechanism | Inverting |
|---|
| Cation dependence | No |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-glucosamine |
|---|
| Donor CCD code(s) | UD1 |
|---|
| Acceptor substrate(s) | [(1->4)-N-acetyl-beta-D-glucosaminyl](n) |
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
1614 aa
MAGPAPSGRTPSHAQSSLPSLPAHLQSDTHLTAHLASRFHVGLPTARLSSQALISLNTYTTSSRGPDGDKEGSAMGEAEDLAKRAFTRLGARGENQAIVFLHSSGESGSGKTTIRSHLLSSFLSFSSTPLSSKLSYAAFVFDTLTTTKSVTTPTASKAGLFLELQYDGSSSVNPTLIGGKIIDHRLERSRIASVPTGERSFHVLYYLLAGTSAAEKEHLGFDSSIHVSTSGGKLSGASIGHKRWRYLGHPTQLKVGINDADGFQHFKTALRKLEFPRSEIAEFCQILATILHLGQLDFVSGQATTTTAEESGGYSHEGGETVTVVKNKDVLSVIAAFLGLGVEELETSFGYRTKTIRRERVTVMLDPKGARQNADGLARTLYSLLVAYIFEGINQRICAAEDSVANTVSILDFPGFSQASATGSTLDQLLSNAATESLYNFCLQSFFERKAEMLDREEVTVPATSYFDNSDATRGLLKSGNGLLSILDDQTKRGRTDSQFLESVKKRFENKNPAITVGSTGQGTTLISQGARSAFTVKHFAGEVDYPVQGLLEENGDVVSGDLMNLMRSTSSDFVRDLFGQEALQTVTHPQERTAIMQAQVSSKPMRMPSMARRKAGPSRLAFDAPEGDDQDEYDSQAGSMSKSSARRKSTMLANGMQGAAGQFLSSLDIVSKCLNSANLNPYFVFCLKPNDRRIANQFDSKCVRAQVQTFGIAEISQRLRNADFSIFLPFAEFLGLAEIGNVVVGSDKEKSEVVLDEKRWPGNEARVGSTGVFLSERCWADLAKLGERVVPVFPAEGSDEGGDNLLHARAGGYADSKVRLLGPTDQSPGGFIYGEDGKQGYSSSREFDGRSDAGASAFNSGDMFRNLDTREQMLEKGNEKKMEEVDEAPVSGSRKRWMAIVYLLTFYIPDFLIKTFGRMPRKDVRVAWREKLAINLIIWFSCAFAIFFIVAFPGLICPTQHVYSTAELSSHNGKDGHNSFVAIRGIVFNLDKFMPSHYPDIVPEKSLKKYAGTDATGLFPVQVSALCPGKDGSIDPTVLLDYSSTNVSGSATTVSTSDTNWVYHDFRYFTNDSRPDWFQEQMIMLKANYFKGWIGYTPTYMKTLGDKSQYIGSINGRVYDLTTYVAGGRRVQAPVGKSVPANVDRDFMDDLVVELFQRLPGQDLTKYWEDLQISDVMRERMQLCLDNLFFVGHVDTRNSPRCQFARYFILAISIFICLIVVFKFLAALQFSRKNLPENLDKFIICQVPAYTEDEESLRRAIDSMARMRYDDKRKLLVVICDGMIIGQGNDRPTPRIVLDILGVPESVDPEPLSFESLGEGMKQHNMGKIYSGLYEVMGHIVPFLVVVKVGKPSEVARPGNRGKRDSQMVLMRFLNRVHYNLPMSPMELEIYHQIRNIIGVNPTFYEFILQVDADTVVAPDAATRMVSTLLADTRILGVCGETALSNAKTSMVTMIQVYEYYISHNLVKAFESLFGSITCLPGCFTMYRIRSADSGKPLFVSKEIVEAYSEIRVDTLHMKNLLHLGEDRYLTTLLIKHHPKYKTKYISAAKAFTIAPESFAVFLSQRRRWINSTVHNLIELIPLNQLCGFCCFSMRFIVFVDLISTIIQPVTVA
Catalytic domain sequence
395 aa
IVVFKFLAALQFSRKNLPENLDKFIICQVPAYTEDEESLRRAIDSMARMRYDDKRKLLVVICDGMIIGQGNDRPTPRIVLDILGVPESVDPEPLSFESLGEGMKQHNMGKIYSGLYEVMGHIVPFLVVVKVGKPSEVARPGNRGKRDSQMVLMRFLNRVHYNLPMSPMELEIYHQIRNIIGVNPTFYEFILQVDADTVVAPDAATRMVSTLLADTRILGVCGETALSNAKTSMVTMIQVYEYYISHNLVKAFESLFGSITCLPGCFTMYRIRSADSGKPLFVSKEIVEAYSEIRVDTLHMKNLLHLGEDRYLTTLLIKHHPKYKTKYISAAKAFTIAPESFAVFLSQRRRWINSTVHNLIELIPLNQLCGFCCFSMRFIVFVDLISTIIQPVTVA
