Home/GT Families/GT20/tps-2
tps-2
Caenorhabditis elegans · Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2 (EC 2.4.1.15)
GT20Model organism · annotation ≥ 4Fold GT-BRetaining
External resources
Identification and annotation
| CAZy family | GT20 · CAZy entry |
|---|
| Gene symbol | tps-2 |
|---|
| Synonyms / alternate names | - tps2
- Trehalose-6-phosphate synthase 2
- UDP-glucose-glucosephosphate glucosyltransferase 2
|
|---|
| UniProt accession | O45380 |
|---|
| NCBI Gene ID | 3565050 |
|---|
| Source species | Caenorhabditis elegans |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 4 |
|---|
Function and localisation
| Enzyme function | Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2 (EC 2.4.1.15) |
|---|
| Subcellular location | not curated |
|---|
Structure and mechanism
| Fold type | GT-B |
|---|
| Catalytic mechanism | Retaining |
|---|
| Cation dependence | No |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-glucose |
|---|
| Donor CCD code(s) | UPG |
|---|
| Acceptor substrate(s) | D-glucose 6-phosphate |
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
1229 aa
MGSEPPPSEKKVREPFSRAMKDVQISDEQRLKELWHLLDLLEIEYKKTADLHTLISSVSESLTMVWKRRDPKSELALKGLLLILEYCLSHVFDGHAVFEIFVSSLGFNTVIFWKHCAGYIFDSDLGRGTKFRDALLFSLTLYDVNTGKNRLRELYAAVPGIRKSLLGVNAKQFGERYHHLQKRLARYGSHTSLCSVSSDSEGEEAIHNVRSGTHTESESEEDPKAPRSGLATSHFQQRVINVSNAPPVSLKREKTGDWEIKQGSGGLVACVDPVMSKDHENLWLANLGMNINDKKQKRPGSVASIPESFPSTNTLGLPLIKQTIAEVFFHVLADDDMDAPKNEKQKKAREEMSLLGVLNNYNRGNYKLNPVVVQEDDYNVYYGGISNGLLWPALHNLPEYIVSEYDDEKILRAHWCAYVRVNYQFAIDAVRNSRPQDFIWIHDYHLMLVGMIMQSLDQHLEVGFFLHIPFQPPGEFFSKYSTVGFAVLRGLLRFTKVGFQTHRDRTKYIELVQHYFGTAKIVYDNKMDIYSITNEGWTCSLGVFPVSIKNDDFLKFVDLPETIKLKNDLRKRVMGDTPAPDGRFFFSVERFDYTKGIMEKLQAYKRYFERHPDRIGKDVLFQIAVTNRRSVDTYRVYQDECIDLADKINEIFKDPNNPTWKPLVFQTDGLPRSELVAAYLAMDIGVVTPKKDGMNLVAKEMLVCNPKAGLVLSTGAGSEIQFTTAGLYSDKEKNYHRISNVFDPDSYCDAFYSAALEPEDVRAEHGKRLHEFIMANDIERWSCAFLDPSWTHEVIRPTQVETLDDFFSLMMKTRNVRRQIVGRVLKGIPIRSHFAISLRNAKESLEQICKPGTHTAEFKSGPDSKEVAHFEIDNELQEFERDLSFIDYVQSDDADNVEQFVDTLISSHPISVETYKKEVENAVELLYSADHFHYFFTDRDGTLKSYSCSYPSSIQPAYSGVIQAQFARRCAQTCVILTTAPLMHIGVLDVSTIPNGYYYFGASGGREWFIDNGHNFKDESILKGEKADVLASAYTRISHLLEEPEFRPFTWVGSGLQKHYGHLTIAFQDVYKTITEAQGKQLHEEIEKIVKDVDPHGTRLQLASTEFDIKVYMKTETDGHVFDKGDGLRLLCEKMHCDLTEGNVLVCGDSSTDIPMLKECLIRNPKGVYTIWVTVNDKLKEEVRALCASYSNSNVAFVSCPEVLLGAMAQATIREITITRTRKMSRNIV
Catalytic domain sequence
550 aa
RVINVSNAPPVSLKREKTGDWEIKQGSGGLVACVDPVMSKDHENLWLANLGMNINDKKQKRPGSVASIPESFPSTNTLGLPLIKQTIAEVFFHVLADDDMDAPKNEKQKKAREEMSLLGVLNNYNRGNYKLNPVVVQEDDYNVYYGGISNGLLWPALHNLPEYIVSEYDDEKILRAHWCAYVRVNYQFAIDAVRNSRPQDFIWIHDYHLMLVGMIMQSLDQHLEVGFFLHIPFQPPGEFFSKYSTVGFAVLRGLLRFTKVGFQTHRDRTKYIELVQHYFGTAKIVYDNKMDIYSITNEGWTCSLGVFPVSIKNDDFLKFVDLPETIKLKNDLRKRVMGDTPAPDGRFFFSVERFDYTKGIMEKLQAYKRYFERHPDRIGKDVLFQIAVTNRRSVDTYRVYQDECIDLADKINEIFKDPNNPTWKPLVFQTDGLPRSELVAAYLAMDIGVVTPKKDGMNLVAKEMLVCNPKAGLVLSTGAGSEIQFTTAGLYSDKEKNYHRISNVFDPDSYCDAFYSAALEPEDVRAEHGKRLHEFIMANDIERWSCAFLD
