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cgt-1
Caenorhabditis elegans · Ceramide glucosyltransferase 1 (EC 2.4.1.80)
GT21Model organism · annotation ≥ 4Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT21 · CAZy entry |
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| Gene symbol | cgt-1 |
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| Synonyms / alternate names | tag-217 |
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| UniProt accession | O18037 |
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| NCBI Gene ID | 188169 |
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| Source species | Caenorhabditis elegans |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Ceramide glucosyltransferase 1 (EC 2.4.1.80) |
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| Subcellular location | Membrane |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-glucose |
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| Donor CCD code(s) | UPG |
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| Acceptor substrate(s) | - an N-acylsphing-4-enine
- an N-acyl-15-methylhexadecasphing-4-enine
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
466 aa
MEAANEVVNLFASQATTPSSLDAVTTLETVSTPTFIFPEVSDSQILQLMPATLYSGMNWLRDHLDGFSLLALSGCIFVSVLYLVHIIAFFYSIYRLHHKVEPDPTLPGVSVIKPIVGTDKNLYQNLESFFTSQYHSFELLFCFHSEEDEAIEVVRSLIKKHPNIEAKILFEGEPVGMNPKVNNMMPAYRAARYPLVLISDSAIFMRPDGILDMATTMMSHEKMASVTQIPYCKDRQGFHAAFEQIFFGTSHARLYLVGNFLGVVCSSGMSSMMKKSALDECGGMEKFGEYLAEDYFFAKALTSRGCKAAISTHPALQNSASVTVLSFFNRIGRWIKLRIAMMPHLMVVEPLQDCVTSGLIMAFGLNYLGGYSVYKTFGLHLFYWIVMDFSLMTSMQNGKFNFTPFLFVFIWLFREFTSPFIFIKAVLAPTIVWRNNKFKLSWGGRIRTSKNSQKVPEAVSLSKGAV
Catalytic domain sequence
242 aa
PDPTLPGVSVIKPIVGTDKNLYQNLESFFTSQYHSFELLFCFHSEEDEAIEVVRSLIKKHPNIEAKILFEGEPVGMNPKVNNMMPAYRAARYPLVLISDSAIFMRPDGILDMATTMMSHEKMASVTQIPYCKDRQGFHAAFEQIFFGTSHARLYLVGNFLGVVCSSGMSSMMKKSALDECGGMEKFGEYLAEDYFFAKALTSRGCKAAISTHPALQNSASVTVLSFFNRIGRWIKLRIAMMP
