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KDTA
Arabidopsis thaliana · Probable 3-deoxy-D-manno-octulosonic acid transferase, mitochondrial (EC 2.4.99.12; 2.4.99.13)
GT30Model organism · annotation ≥ 4Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT30 · CAZy entry |
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| Gene symbol | KDTA |
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| Synonyms / alternate names | - Bifunctional Kdo transferase
- Kdo-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
- Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
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| UniProt accession | Q8VZA5 |
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| NCBI Gene ID | 831727 |
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| Source species | Arabidopsis thaliana |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Probable 3-deoxy-D-manno-octulosonic acid transferase, mitochondrial (EC 2.4.99.12; 2.4.99.13) |
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| Subcellular location | Mitochondrion |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | CMP-3-deoxy-beta-D-manno-octulosonate |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | - lipid IVA (E. coli)
- alpha-Kdo-(2->6)-lipid IVA (E. coli)
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
447 aa
MKLGVFVYRLYRALTYGVSPLIHLHIRWRRLRGLEHFSRWPERFGHPSAVRPPGSLIWFHAVSLGEGMAAIPVIRHCNEVKSDLTILMTTTTVSAFEVIKNQLPVGVLHQFAPLDTPLAIDRFLGHWKPNAIIIMENELWPNLIMAASGLLIPLGLLNARMSTKSFKRWSSPLLLPLVSLLLSKFSLIAPLSTLQGIRFQLLHAPPFVINYSGDLKYVVNKFHVSSGTSESIRDLKVELAEMKVWIASSLHRGEEEVILGVHNMLLESHPDSVVIIVPRHPHHGQQIAHKLRKDGQSVALRSQNEKLTPRKTNIYVVDTLGELRELYSVAPIAVIGGSFIPGLTGHNLSEAAAAGCAVITGCHVGHFSHMVKAMQQANPLSVTQVSTKLELKEAVDLLLSNPEILETHQRASKDVYESLSSCIITNIWKLLNLHIFRGKSRNHIECK
Catalytic domain sequence
189 aa
AEMKVWIASSLHRGEEEVILGVHNMLLESHPDSVVIIVPRHPHHGQQIAHKLRKDGQSVALRSQNEKLTPRKTNIYVVDTLGELRELYSVAPIAVIGGSFIPGLTGHNLSEAAAAGCAVITGCHVGHFSHMVKAMQQANPLSVTQVSTKLELKEAVDLLLSNPEILETHQRASKDVYESLSSCIITNIW
