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Chpf
Mus musculus · Chondroitin-polymerizing factor, non-catalytic subunit
GT31Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT31 · CAZy entry |
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| Gene symbol | Chpf |
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| Synonyms / alternate names | - Css2
- D1Bwg1363e
- Chondroitin sulfate synthase 2
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| UniProt accession | Q6IQX7 |
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| NCBI Gene ID | 74241 |
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| Source species | Mus musculus |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Chondroitin-polymerizing factor, non-catalytic subunit |
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| Subcellular location | - Golgi apparatus, Golgi stack membrane
- Cytoplasm, cytosol
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | Yes (Mn2+) |
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| Oligomeric state | Interacts with PRKN |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | not curated |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
774 aa
MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGSERERPGAGAGTGESWEPRVLPYHPAQPGQATKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTGARGRRTPSGMAVVALGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLDRLAGHLSLASATHLYLGRPQDFIGGDTTPGRYCHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEWLGRCILDATGVGCTGDHEGMHYNYLELSPGEPVQEGDPRFRSALTAHPVRDPVHMYQLHKAFARAELDRTYQEIQELQWEIQNTSRLAADGERASAWPVGIPAPSRPASRFEVLRWDYFTEQYAFSCADGSPRCPLRGADQADVADVLGTALEELNRRYQPALQLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRWPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLASGFLEAFATAALEPGDAAALTLLLLYEPRQAQRAAHSDVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGHFDRQAASEACFYNSDYVAARGRLVAASEQEEELLESLDVYELFLRFSNLHVLRAVEPALLQRYRAQPCSARLSEDLYHRCRQSVLEGLGSRTQLAMLLFEQEQGNST
Catalytic domain sequence
500 aa
HLESCRNDIVSARPDEWLGRCILDATGVGCTGDHEGMHYNYLELSPGEPVQEGDPRFRSALTAHPVRDPVHMYQLHKAFARAELDRTYQEIQELQWEIQNTSRLAADGERASAWPVGIPAPSRPASRFEVLRWDYFTEQYAFSCADGSPRCPLRGADQADVADVLGTALEELNRRYQPALQLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRWPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLASGFLEAFATAALEPGDAAALTLLLLYEPRQAQRAAHSDVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGHFDRQAASEACFYNSDYVAARGRLVAASEQEEELLESLDVYELFLRFSNLHVLRAVEPALLQRYRAQPCSARLSEDLYHRCRQSVLEGLGSRTQL
