Home/GT Families/GT32/afp18
afp18
Yersinia ruckeri serotype O1 (strain ATCC 29473 / DSM 18506 / JCM 15110 / CCUG 14190 / NCIMB 2194 / NCTC 12986 / 2396-61) · Toxin Afp18
GT32Non-model organism · annotation 4–5Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT32 · CAZy entry |
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| Gene symbol | afp18 |
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| Synonyms / alternate names | - Antifeeding prophage 18
- Antifeeding protein 18
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| UniProt accession | C4ULG3 |
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| NCBI Gene ID | 66880871 |
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| Source species | Yersinia ruckeri serotype O1 (strain ATCC 29473 / DSM 18506 / JCM 15110 / CCUG 14190 / NCIMB 2194 / NCTC 12986 / 2396-61) |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Toxin Afp18 |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Retaining |
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| Cation dependence | Yes (Mn2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-glucosamine |
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| Donor CCD code(s) | UD1 |
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| Acceptor substrate(s) | L-tyrosyl-[protein] |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
2123 aa
MPYFNKSKKNEIRPEKSKEEVGGVLFDDSAIHENIDHNMEPQTGDSVATFPDNSDEVVGGDLAALRARLQATIGDYLPEFYEFQQTGRNILYPKPVDIKALQARLNSMPITAWIQPLQQQLEQAGNAFLDRFRLFRKEKDWHNNALEFVKFRLAVKETGWDEQQTRDYNEALKHANRLSGYLSGTLDLIQHLNDNPERQTSWEAVRKTSYDMLLNELLPVDAENNGNQYTAKIRGNLTKNHPDNIKFNTIVNSVTRDERMASEALSAETKGLSARLLSGIALTRNSAEKIDKKSETSGITRDIVALCQVLQGVIKTIKRRGEYIQPLTDWQPSEHKLPGQKEELTKAETVKRELVKSRKVMMQKVQGAKTILGVLSDKTNKNRHRITQTLPYSANPDTNTVSRKTNEAVFRAGIMLLDKIQQTTSGIHKASLASRPLQHAVTQYSALEQMSSGMPSNRILDAKLRSESGRWQEKAEKSKKQLQHILREITALAEEHLKHKFMSALRDELKRAPETLASNNIISNFDTRAKIVVEGLASIEIGMNQSVVRLAGHGEAGRKDLDEQVVAWLQRLERIKGELKTDITQATGQSINNFSRQGMLARRMGEWNEAEKQRYLAALSTEDRAVAEMQYNTLFFEVIQHYLPLLSKETDPQGERLLQRLRLEVSNAAEGTTVYPATMAEILAGMKSTEQAIRDWSGRKLLRVVFLAACLEGVKLMPKLAALPLRVAIKFVITGAKVAWATHKGQQGIRGGEGDVDDEIGEYAKRSFKTASVKVVLSLPPGLATMLGVASIALDVYEGGLKGAGGKIAKNIVGDAPWRALNQGSKIAAEAYTTASMNAALKEGGANPVSHSSTLQQQMDAKPFFDNSDQDADQPRVRRKREMTDEIMLSDGSSRSEAKALPDENELDTDQSKSRPESALAVETLQSEHFDFDRGIRYQDFSDEQKKQTYLHGIKFVLLQIENDGHFAQNIRNNAYLARIGAKLAVPVDIYRYKLNNTFLLPDEIDSKSGVLIRLDSEIPYYYVSEGKDLLENIAWAMPYNAANRGPLKFSLDPGEVTSSHSGVDILNNIRSERFKFETYFNYNAPEAMSIESLSAQLANTIEADYKFKNTSPTNKILISRAIVGAHIPDPGVRATQGEYHIEFDSDELAPAKYLRSFARPFSTLSGEMQLISSSIKGETIQETELHVHQAEYIGSWVDATAGAIISFTPEGWFLNTAQSAAEITADLTEGKDPDPLAVAGLLVGIIPGGKIAAKVGKFTRIGGKTVKYGLILGNKSVDLAIVGKSIKTAVDTGEPLAIYQAFLASGMSVKNSYDIAKNMSSELKISKKIEESARLRKLKALQKNTYKYSMNSKMPVRKFRVGQTDLLGKIHKGEIKISRNNGTTWEKGNQLHLLAYRLQNAGGGRLLPDVFRDKIVIGEYSFKRVKYNQKKLNEMMRIAKMYTPTSNSTERIAKLQQNYKTGKEMSHAPQYDTYNDLSLGEKLDLFINSNTDATTRGVLAGKINESITNINLYETAKGVDAWKTSANKATDVVLAPQNIFLKGRAGECLPESILMGWALQSGQDTKLAKKLMNIHSSSNIAANPLYKSLVELHSDGNASRFGESVISDINMKMLSGAESKLFPTENSSVRVDIPEHTMLISKVNKDGKIKYVFYDPNYGMAYFNKYKEMISFFKKKIKGYDTPKRSTSFRQLDYSHLSDIKIKGKNLNEIIDGEIPQIFRQEDVNLEGITPQDGIYRMLGTHQQENNTYIKSQNNIYQVEWDQTTNTWRVFDSANTNRSRITVPIKRDTDGEWFKYTETGLKGGGLFDEIKNNWLQRKRFKNLQDFNDIVDFEENKWPSEPINKDIHMIWVGTRNISEKNIGLSLETARKNSDYNTTIIYDSGIAGYESAKDFMTEKFKDSKVTLVDFRKKSYFHQLQQEPSFPYYEQAIRDKKYAQASDILRLLVLKYEGGIYKDIDDVQVKAFGSLAFPKGIGVMREYAPEAGKTTAFPNTPIAATKNNPVVNKTLELAVENYHRGETNVLKLAGPDVFTESLYQEIPGMRPQVLGAQLDQFELAKRQALGMRLEKPKGFADEKLTLQEKAKIRQPYEAIRGLSGYVDNGADHSWVTDMPGNSTQSSGLS
Catalytic domain sequence
53 aa
YFHQLQQEPSFPYYEQAIRDKKYAQASDILRLLVLKYEGGIYKDIDDVQVKAF
