Home/GT Families/GT32/alpha4GT1
alpha4GT1
Drosophila melanogaster · Alpha1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.-)
GT32Model organism · annotation ≥ 4Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT32 · CAZy entry |
|---|
| Gene symbol | alpha4GT1 |
|---|
| Synonyms / alternate names | - Alpha1,4-galactosyltransferase 1
- UDP-GalNAc:betaGalNAc alpha1-4GalNAc-transferase
|
|---|
| UniProt accession | Q9VQK4 |
|---|
| NCBI Gene ID | 33512 |
|---|
| Source species | Drosophila melanogaster |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 5 |
|---|
Function and localisation
| Enzyme function | Alpha1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.-) |
|---|
| Subcellular location | - Cell membrane
- Golgi apparatus membrane
|
|---|
Structure and mechanism
| Fold type | GT-A |
|---|
| Catalytic mechanism | Retaining |
|---|
| Cation dependence | Yes (Mg2+) |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-galactosamine |
|---|
| Donor CCD code(s) | UD2 |
|---|
| Acceptor substrate(s) | - a beta-D-GalNAc-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Man-(1->4)-beta-D-Glc-(1<->1)-Cer
- an N-acetyl-beta-D-galactosaminyl derivative
|
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
369 aa
MLLWLPIAVARRMFIILVLMVIGGLFYIYTSENKYHSCFMEGQVLATQQALTADGETNLLGDVLQADPKPSPGNSIFFHETSCRLSENRQLETLKVTARQACAIESAAMHNPNFQVFVLFAGPTYRISNNKSHPQPLLEAILSYSNVHLRRLNLESYASGTPMEEWLKDGRLSRSKYLFSHISDFLRYLTLYRYGGLYLDMDVVVLRNMEKVPPNYTGAESNTHLAAGVMNLAATGFGHEIAASCLRDFQHNFNGGDWGNNGPGVITRVAQKICGTKDIALMREDPKRCMGFKVFGRGAFYAVPWKQWRDFFEPENLEETIARCKDSYVVHVWNKHSSKLPIKIGSKNAYALYAEQNCPRSYKAAGEYF
Catalytic domain sequence
131 aa
TGFGHEIAASCLRDFQHNFNGGDWGNNGPGVITRVAQKICGTKDIALMREDPKRCMGFKVFGRGAFYAVPWKQWRDFFEPENLEETIARCKDSYVVHVWNKHSSKLPIKIGSKNAYALYAEQNCPRSYKAA
