Home/GT Families/GT4/glgA
glgA
Velamenicoccus archaeovorus · Glycogen synthase (EC 2.4.1.21)
GT4Non-model organism · annotation 4–5Fold GT-BRetaining
External resources
Identification and annotation
| CAZy family | GT4 · CAZy entry |
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| Gene symbol | glgA |
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| Synonyms / alternate names | Starch [bacterial glycogen] synthase |
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| UniProt accession | A0A410P257 |
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| NCBI Gene ID | not curated |
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| Source species | Velamenicoccus archaeovorus |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Glycogen synthase (EC 2.4.1.21) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Retaining |
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| Cation dependence | No (Zn2+ structural only) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | ADP-alpha-D-glucose |
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| Donor CCD code(s) | ADQ |
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| Acceptor substrate(s) | - AMP
- [(1->4)-alpha-D-glucosyl](n)
- a gentamycin
- GTP
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
32767 aa
MKAIAWLIVLTFLPEQVAWAVDYNLRGALHGAVAPLVSAATVATDGSVLQKTQKDEAFDRAIADAIVSSLQPLIGKPATDIRLSRQVSVHRNYPLNLTQNKIDELHAWMMDSGRNLVTCGAYALSGFLEAMGQKISPYQMAQSALLIDILSDSLDIYTYNQAKKLENSLYALSQTALLYGYELKPFYWKDFYSNTKNIAKALNKLIPYIAFVDDDHMVLVKGLSKGSVVIEDNGKKNIWTLAEFERRFSKYGLALSSRIPQGYDIEILEEAVAKAVQGASRKHYDEITTIDDLWKTSESDVWLSALTLAGTFVLGGLGGFSGLGQAAQTGQMAWSTSAATQAMLTGLAASQISSAATNIAATQFGFSSAAAQIFGAMAGGAAGGGFSQSFGGAAGGYWKPSDMGGNAFSNYLSQHATLGAMTTGAIQGAFTGTAQVFAEKSIGSDSIAAKLLYGLGSSVVGYVGAEYTLNQLGYNSVYQLSEEDFKAHTNGNGTFDQKTGSYRVYASDYKEGSSKWWNFLGNTALAVKDIGFQRYTLSNLIGTALEQIIGEDDFGYSRILGQTAGSLVAGKIYGGSQSYVLDAILSGASSALLATMGGKFDKETGKNSWGMTATQMALFNFGMTSMIKAGYDAFSAKGEGQSFSNVFTQSLLGSTKDLADNLFFFGKTSPFYSPETMSSFRSWQYTEKLLDFAGVSKFYANANQIMKDNDMSWEEVVDNGYVDKITRPFGNAFVGYVSSTLHYTAADNLAYVMNRGINAIYDKLTEVKIKTLPAGKDPVQVILKLQTDTAALDAALQAARDGESTSMENLLSLTAGQTAVMEITRGGKTQVLQYDPANPLAAIDASLIIGADRADIKIVLPGMSVDQQAVIDNRAVFDQEKLASGITDPGMKALYQSFIGSWRTGEGNTQIEMTSADKQGVFAKFLGLGTSKGIGYVSPQNGANSLVGFDASGDVTAARSWSYREGKGFFAWLLGRTGSSGYQTTQNYGGVNGVVTPDRYYDVREFNVVNGNRRNEVIYKGFTGTYTSTVNVGAKPEAITRSAYIMGAFVPNRLLTGNKEDIGYSVTGLVTGASRYADPKNVIQNPAVLMPTLGSAASTTEPGETKGFEKATFGSTYAEIKNITEAGTSYSVLQGNDKAKAETITINPDLMQLQLNRASDQVVIAQGTPRLPYGSVLRISAWTDPGVINGEKEKMYKNVSLVFGNPFKQQVNGKALLDNVINFYSLPGAGNGWRWDRTFKHILEKAGVDQPVAPKPVETIEKKLETLRIESPAVAETKIKEVFGADAKVVLITPQDSGIDPDLAKGHLAYNINGEIYNLIDNQLVPVTKSPSDTTANMPVKPELVTLPSGEPLPVSQTPETVTAGTDVAKTAENPGRVAGGQATVWAKLSEELTGINSWVVRGGEADATRSFLASSAAGQVYTAPVDKIWADDKGRWGVVAHVMDRKQGIIHGAELLDKTYLPQSFPSGQGKSEPQKDAIRFADDAYKLMVASNSEFRQEGLVKFTTGTELPLFIGRDNEGKLIVNSLAGVSGTTLIAGPDTTIGTALIRSGNADARFVSRIVTDRATGETSQNFNGTTNGLEVVRSLIGKGSRVTQPDVVRGINGDTVTRVMSISKLDSVLTAQAQGDAFKSWASHFDIAAIQKLTATHKAGGTELTETKSVPMAGRLAVMNVTVNGKSSQQLVVPFSETWWIHPSNVAGDGSKSSTTLAVEKGAVDLISSVLFDGGLVIKSTQGKTPVPLTINIAQQGYGQYAIGGFDTSLLSAENATHTIGATFTYGKNAENEKVLDDSQMVPFGRGFRVGSASAGQSVTVTFKNNMPWGMDVNGPGAVVRDMGRLNISLGTLYNAKAGEVETAKTIERAQAHLTDVKVLYLLKEAGAQTAGQGWLPDYTRSQARGTIESWYGTEKREDATNVLTSRVLGLDGIVQVNKYANNKNERNVIPALIAEGQGDKGGIYWSRSGGAPSEPTAAIKAGKQPYNSFLVLDPGDTKVVTSMADPSKGIIVSRGLFRLELNQNEQGDFIGFGHQALTADNAQHTLKLSNGTTYTYVPGVRNEENPEASKPAQLLTSGMIPLSDKIKVGARADQEDAVIIFDHNESQYGFRAKTPAAIVYDMGESMRLYMTPLWNEKTKTYGPGKGPVYGVMDLKDVALLIKTDGLNKEGHNDWLVDYKHSQASGTVKTWVHQMSEPSDPGKIAHATVLGFGEMTQVQGKESVNIPAISAVGATFALRNFGDGSGDAGSYSRVAKGAVDVETRVIQAGSMGMISEGKLLFELQMDKQGAIIGFNNQALFADNARHTIGGGYKFTAGNGVDVPDTLDDSNMVAFGKDFRVGAKSDKTPAVVVFDHAAMWGVKTETPAAVSYHMNNTTISLDPSSSIAGVRGTAHLRDIKVLYTSNGPGAKDTFAQIRTPDFSSSQVRGEVVTSTNGKKAQFNIMGFGELTSGNGGEVPALKGYGDIIWARNFSGGGKGGNNYLSITRGTVDVSSESLSAGSRVIKSHGHILTELQTNDKGIFSSFGTQAMTADGAIHRTPTDTRRAPMLLKDMFVYGTDLKFDHTKPLGVSALQGHNIRAVTSASTSLGDGRKLTPLTAYQVTFNDESGQMSIAAGARFKDQSGNVFKTTEQGVELVSGPMKDANDALRERNRQQAAAQTAAVSQKREGLERKLKEAGDDLRRANDRYKREMGKTDWFWLRVNNSKEEGLLKSAQDRYKSAMREYATFLRDNDWNALDRLANPGPSYDERYDGKGADHYRTRFGLETEVANDVIKTTKGRLGVMEAVRRVQEEYNRAVADLNYFAESKNKLTASGGTRLINTTGQLWDTPLHFKEEMDEGISMWRDAFESNAKGRMQNIAHLEALLKQEGKTLSQTQVQQIQTLIGEAKGLYDRVGSGNDKQVEAILETNGVRVWLNKHTKFGYDYNPDWGPQGIVKGAGAVVGYAFNDVVWPVIFGTYSAAKGGVIDLAGTVAGNKGWKQAADDSYAGSIMIWANSFVGDSMQLVSGDQAAVTWVEKAIELSKPGTLRVNKTGADWRDWEFVGIQDGVEVSFRGSEVTAFAGIKMAKEVGKAQWERGDKLSGGFNVAGAYAAQTLKAIDELLMSGKVAGVNVGRTAVVGVSLTVPTVDVIKYKLTGEYLSDSEGTTLAISFLLPAAGAKLAASGQAALSTVTAVEGSVWTARALTVANAALKIPQAANVVNLANFGLASGHLTTTMTTGSPMDLTQSMGNVLTTYGLVGAFQTIGTAVRGTYAVQNASRATTYLIAGKAAAGAGLSVGTGIYRSEISSIPQAGWYAFTGAVGGAASYRVNNPIAFAATSGLIASAIRQPFKSNVDSVGSALLNIGKDTFVSAGIGLLANKAPQIGSWLNEQSFVTRHAVILGSGALSFGIARDYINSPSLNPLTTFNTPGQLLVSGVKGAFIGELVAYGAKQYTLGATGQVASIQANTAKFADLNALTTEMYSSAKSWWLVSGVMSGTKPFVDTALATVEHGTDWAVDKVLGSNFSQGQAVFGFYTPVRNDKGEVTGIQRSWLRDMGQAPQRIADPLTGETKTVYESFSFGKYYGSLDNGGFLYSLANSPREGMMIGPIVKIMSRTPVTPEETLLGRAPVIGSSVAKLETGFLRMQEGWAKELAGTSLKDLIAAGDLSGAFTVAKAGALSFGAKAVSLGKVGFTVETINRTMQGVNRLGAYVDAMTGDLDATTLAQVGTDSYATSHYQGFSAADMQILPWAALFTMRSAALPEHIAKMYYDQGQFGLATQKFAELAGRNPADAEAQYNLGLSQRAAGQKDLARASFERAESLAREAGNMELGRLAFSQRLVGMDHVQAEALLGDTIRQTSAARKEALGSGDLQTANSLKAELSFLGETRLVVRGQMEAARNNTERAATLFRAALRLNPANVDAQLGLRSVDPIQLLGLPDSADAAQVQTAVSLRRDGLERQIANRMTEIERLRNRVEELKAQGNTTGAAQWEAQIKRLEARNESAQRHLSTLPQLERRAMEQVTQIAKGESSTTSPTSVSVPMPKERTRIERAVAEQKDRGVAAGKLSGLDVVLLEGTREGYIVGKHRAYVDVDSSTIYVASEFWNQAQGAARTSELGRELTTLRVAARDYSRLILSAQETSAVLEGRQSVRQAVEDRLLDAVSTQGKIKGLSPIQVSLRLNEMRQGVMASYRQAEIVYKFDKALRNAKTPADLRVAIQEAGGGGKTFVDVTLLPSLVAKNKAFGGVTAMTTYGDSLSLELANLAKAVYGDRLGEIRYTNRSTSHSLNDFGSKIEVLSFESFTNLVHAQKYADKTGDAAAPRLDMPRIKNSIFLIDEAHTIGMLPGIREGQGTEAIITGKAQYEKMRKEMTNLERQTNIKGRQAWQEVQNSSVNITPGNYYETLRSSFGDAPLTGEQTQALDKAKLADAYFRVREYEMYQKAQQRGEMLQTSLSSRGALSQMTPKIAEAVSQAKQSEPLRYQSASDAAIARSILLERQGAALGREFADILGSSFYRQKYADMLTARDAKSADMAASELGKVVLEGATRAAQYSGNEYSVTKYNIEVLAGSGKADGRLHLPMGEMQALQIKWDKPLTRPLGDTMDVTQSFEALKEIGGGLMLSATLASGTIAERKLSEIGYKTLEKGVKPVLSANKQEELAKNAPAMYRQMYDEMQGVGFDKAGQFALFSGHRQVKEFNQYLENVHGVQRVRGLAGEGRTVTGQNLVFGPTMPDAVEAAQIRGVADVSSPVRVITGTVAQVGTGIDVAWANGAINKKALHLAYPEDITESEMIQAFNRIMGNRGIGMNPEVWIYTNTEKLDATPGFSAYKPKEGWSVDAWDSHLNTVQATNEFYKTQLSTVSYERQAPASEYKGEANITRGSPKTVEEFATRLVDRGVISAEQKTDFTTSFTTQNSCLVGQNGTLSDAGRSIAGLSLVVLEGTPVQQQSFNVAVSTLNPSSGINVNVSAAPASQAPVLTPIQTISAIQQLSSQGIIRLNDNGSTLSSFIQYGSLAGIAPEKFAGKVGTADLTRAIGYAQIDSVPYYFTQVLVNALPADDAFRSAVAPMVASQREAYEGLNTATNDFLRSMQKGASAAEQKLLGVKAQEAGRTFEQAQPTMASLGSAAQAIPGASAESLIPWFTPHLQNTTTMANVIGGGVYNLKRFNVPMDKMTPQQIVGISTSYAASDILRALPKKAASDTAKLAQAVSRLVRVQQSLQLLNQRGISQVGNISQETIKALANDDRAFSQLMEIAGRKMTLTMSMPSRREKLVGSILKDISRDVAQLRLQGIEMDGTKNITPAMILLTARSVVKEKSISDVQEANELTRNLANDAALMVTGLGSAQPVAQEFEAFKTSADEAIAKVQTQATELNQTLELLSQKQAAIQRTPEVLAGLSSQDRDWNLAEMLLVSNLRSRVLAGEIDLAAVSQKLADWQREVSLIAQKGFEQRTRLTAAGLDETAYFQTQESVLAGELAIQGQIQTGIDRALRGAIASAQRKQGLSQLYQQIGFATRRYVPDGFVSKFRQSYYAPIRQYATERQTATHQFETAFSQAPANQALPGLGSLVIGTAYDFSGVALPQVDMSALKSPLWQEAPIHAAFNSSLNMMVYELVGGVQQMINSVRDRIVPAGVSVPQERQWLSARSQTALGTMATILNGEPYWTVSDKLQRLQALSSVPQVLPQALFDRRAQAVSEINVMLQQASQTLPAVILAGVNSELGGNIVTQDQVAAAAQQALGSLQVSVRVAEGLRSVGMAESLRTNGGYSLAINLAMVQPSAATFRPYMQGVIIPHEFTHMIKDILARNILSQADQLGLTEAQRETVSNWQIGRLANERGVDTDVMQNLAQMVSTGDTTAQALSADQDIQKTVANIPGLKSTNDLASYATPEQRSALFSKISATQGIMTYQEPQYPQFTLPVVGGDGATGDVAGQTLTEQPMEGPIGSNPAVAVTAYSSPVVTLRQGVEEMAQLRGLLAGLDAGLMESRIRESELLIASSMPHALAGGGWGGPKVLEGGNPPKIAMVGGGPKDLTDAGNPPKMDEATSPDGSPKPAPARQFADFGEMPIARSNGFGLERERTGAPENDSTSSRFADFNRPSTPKGEREGGVGREGYPQETGDISKGRPVFGNRGSFVGTGVSLALEPMRPSGVTSSISSLISRSVFTNEIDVTSSYNPTTIASSLVLQPVSLNALSQQITLPTLQSPSSISDEDERGYAIDSLSSPARFADLGSSGISPQIFFVETGWWSGREKRTGEVKLNGPDYPISQTIPTLRSFVSRFGRPVEVGGYFIGLNNSQKLTHLVTPSLVIGVDAKPSDFDKIGVNWMRVMPAVELGSNQLGLKLIASTLGTQPGQFQEVTMFFPQSRLVLDRPMHRLLTEEARAKIFNGGDVSQLSDEEINGRIREFIVNRGYDTLSPDVFFEAPYFDKNGQRAGNVRVLDAPIPVETLSSERFFLPTAEFDLKTLFRNSFEDGRFYGRVHTHYTFTDLDVASSAHLQEMRRLDARFEELLTPFDMMALMGSGNMNSLLGEFYNGAPLKSREVLSGVVLFDAITKKPVGSSFLDLGRIPQDQKSLNHITITTVAAHAALESTNINYGVVKEFFGLMRQYSAPDLSQIDYIASSPATSVTSLQQTQQEQVRLRELTGSLDAKLMEARAAESATLATFNINEAPVDVLVNALRNKGFASELPAAERPAALVNVAQNIRVQAQATPFTSLEDLQRRMPEVAGYLGPQVNYMKIPSLSASSNETLRSGLKVSLAGLSSPAEKKINEMAQEELDKLLRESGVSADELEAIELVDLARTTTLSGHQADDVSLEEMSRQRTYIKWRPGSGVISTMQAPDLVVNHKKDIIFEIVNRTGEIRWLDKGALVSDREMAAGRQAATNLWKQRYENKPELPDSSKSSPASIFNVEIPAIPLGRSTEALRNRLDVSMPSAAAYSRAFYVDEAGPVQGVDVNPAEIKARNVDMEELLITNDMAQAEFMSTGFAGCKVFAFEGTKDNRPVLGFAHLGSDHFMESAARIKEIFEAEGIKPQTIILVHSMVSPESSYLQQRNRRDESYMKAIFEGAEIKIQSRPELIKEARFTAEGLQFPRAVLPTLIAPTTISSPAQYYRASRPVYVVRGANVSNADSKTMSRRKFLKIGLGAAAVAAAVGTGVVNYDVFYAPYTDTVLELKDGTMVHIPELNDMDLVNLLKGRTSQEKHSPLYQYLADIDTGVFGMNILSVNRLEKLVRQKQEDDLLYRLDPNSGLAEMMLYQTRKAATALARMRMNDNVRVMADAAHRLQLDPALVAAIALTEQIDNSGSAQTEDLLSFYANVIPQDGSVGLMQIRPSTALKMQGEEGGYFARLSAAWKLLRNDRFNIQTGSMYLRALANEGASKHGLTDLALPSSRWSEESKLKVMASYTANPFTDRIMNLATPPFAAYAAKSREEAGKRDVQEAAVYAHTALAGEKLIRSIEFFPSSPAVNETLRSGLKVSLPGVVSSPAGIQQVMEQFGRRDISLSQHRGLIDEANALLADPANIKIFMDWMRENAQGSWTDVLPAMKVGQIVPVLPASRIETQSLIGALKATRTSEIALSLYRPEGTTFGASDYILTRGAGNNNVHLVSYGAQGLQQILTDASAFGRFQELGFAGDSQAVLLAQASVGTLGFGNLIYRGASEFVHTHPFENAVTPSPADKNFYDMRRTLSSPAALSRRDFLKTAGLSFAAISAFGPEYLFAADAQTKISGIRMKGFDAAELSRISNSLRQINARTPDLLDVARQAGITFVREDKTYAVTAGQMDWAARELKFFNGWQEGISDLTGHISHELGHAVANQAGEGFKNALRNIERQFGVDYETTRTSRENRKLMVVFGARDAFMEQYLTPYSSVDADETAAELIKSFVTQPSELTQAISTKPLVAAQWNALQKFAPAGLRLDVLMPAGMPVSSPAKIQPIAPIAQTALDLRNRQQQPQQENKQIAWEETKPVDFGPAAIVTISDEARRLMEQESKKAGSAEDISSPTSLEGPKTAVMQNDATLSLPATDTRIVYTPLNSCLAVMARNVRTGERQVAHLLASGHRGEDYFVVGGTGNLLNDRILSEVEYLSEKLGDIKGPDWRVAVISSDPQTNIHDVNLNIISVEDIKGFLEYRNGVAGNHIVSDLATNAKDINRTAYLDAEGNVSVVEGDGTVKDVAGLAHIDPLSSAAQPIIPSLVRISGNMTDPQISAVMADMRAKVAGLQETAENMLKGEPLTKAQIAAFKETADAIDLIPDTLVRDELRVMVAESIVPAWTVAMLYGTPHFTPDLIDLGLFRSAMARMETTQAQAVLRNVAAGKTVSSPESQAPGVSSAALSYAYKGPVEFEGAKLQQDLYRRMTLKEVLGHDAFVSQSLFNIHGVLVSPQDIAQIRIKEDGRGSQKHVYLAVAELKDGRSFDFALKLAINSAANFDFQPQETSNLGKLSGRGNVPLPKFGMAIETDEFKAYSEEFINGYTIANKKVPKTPEMIRSVTASWMRVNLFISHFVNKVPLTDTKLYTVKDMAWHNIMIPADAVGRPDLTRAPVVVDVGATIRRQPSAALVEIYRHYQAYDGAAQGVFLGVMDVLGQNQGMIYLQEAQRELHRKYSKDAVETKLQASLESFLGERGISSAATTLTRPSVADISETLRSSGYGVRVEDRVRAAQAISQLAVSSTESLPTLSVTAINAELSSLDLPELTALQVDALETIDALSVPITELEPLSQPLVVDLAPLPALQPLALSMAAGTGISAFASGTSFGVMSGMPGFGPGFGGFGGTLSSPSELPKLPDLGRSREALPHNVLPSLQGPARFDRSDRQALHPIAVPSVLLNAVNVPLVSMQSLTPVEAQKKQEEASPASSQEVPMTPPAPISTGVAAQANAQATNTASGAIPQYGNHASVFLLSNPATSRLMLDVLTYGPSAQEIAGLVSMVNGVSSPARSPGVWAPAGSIPASSSVYHPWESTATGYGKILVVSSNSLEDKELGSVTGNIEISGEAGAQSVICPDRRISGDLVSARSTVVDRAILGVAPKAEGLATVKLTPPNVGTLYGATGLEARIDGSTPTSIAGMPQLRYAAVSETLASASHEDLNRVGETGARGVSCPAVGQRTSLVTHDSAKYDRNTIETTGLETGRLIYAAETQIQAERSLSDLKNTYTLSEEIPFSRIEGLFVPGLLENSPNSTEIVTLSSPALQTTTSFLKNAAVQSRQRLSHFVQKELLYAVILVATAFSGYEVINHHPYLAAIAPMSAWFVLSILRSYSMLGFGIASVFVKKYQPLAPVADQGLPKITVQIPCRNEPFDVAKMTLDSAMALDYPKHLLEIQVIDNSDIRTKDGLPNRNYELLKAYAEEHAGQNVVFIHRDGTEGYKAGNLNLGMQTARGEFILILDVDSTILPFMLRQALPEFYADSKLGFVQLEMVVTNKNENRLVKTLAVGTEIGRSLGTVRTKYGFTTFGGHNGIWRSSVLEEIGGWRTTVSEDLDTAIEARLAGYHGKYIPYVVTGEWAPETLVEFQKQVRKWSFGTTQLFLGRTGKIFKSKEFKWQEKVDLFLHLSTYITAGFIIPLAFGYEFLPHTPSVTASLLLIYGSPMIPILAKSISELRAGNTAKAIKIVGRIPSLTGIFNTVVPTIAMGTLAAVAGKKEGFRITFKGKATQPTLYEVIKSNAFGLSVAALYFAFKGLYAQNLSDVSIVPALAMASMLFGPFLYSDFTWRKKIEAAPAMEAPVSIDEIQESIFADLAQGASFRGLAGALTSGYASLEARPVTTASVNDDTFSSTISSPMTKAAGVSLKSAIEEKFNGLQHTVGPTRIVFSADVFEQEGMENVVAAEINGFWNPRASECPALEYHPAARRGNKILIVSTSVEFTPAGMDVKETNVNYLKANGIGTFTMAALKDIVAAYTQGRARRTHIVNQPTIAVLHQAAFDYGRSLSDARVSALLTQYPQLIGMNGTVLPEALAAIMGLTTSPGIEIATMRDSYVTVLVPALEALEENGVVLETIPAVLQTPLVRVMEKTGYANSRFEFTPSAWDEDLQIHTR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VVRGAEFPWIDDILIKSGKYLQDKVKWVGIKNEAASNWIYASTASIHSAVGIGLSSAWSLIYLAKGTYPHFLPELAWGSAPFIALVGPFAIVFSIVSFALALKTFFAKDLTRGGLIHAWASGTLSATAIVYAATLTWYWPILTAIVVGLFLYGYFLEGTSGVTTESWKDTTKEKTEKIKEKYRSQAKQNTEGQRKHQEEAKRRAEERRKAQEEQRRKAEEERRLAEERRRDEIKRQNIETGENWYRFSGRMTVVRAYELFGLEFGVSLDQVKQARNDLMLKFHPDRARNIDKSRATIISRNVNSAFDVIKTWLQDSVSSPALASYFRIDKVLVKMGRYLQGKVDQPFLETSALAVTALGFGAAIFWSLKLLAGAVYPQFLPILALTSIPYLSVVGPVATIYLVLSLLTSPKFLFDFKAPKISFIKDFAVNLIHIKFIAAVKVLGRFLGGILTVVGIKELTRGELRHAWVSGTFGSAAIVYITTLAWYWPILTAIVVGLFLYGYFLGTTTQTTDRGPAPSDQKEDKKESNKEEESAPKTQKKESAPTIGTEIELTLTERQGDSASKDAVERQRVRGGSKKGQGRHWAPGSRRPVGYAMLKDAVGEHNGDSGIVFDHSVAVEANTGHRSISEITDEVRTFAEQTLKILALIEKIMVAHPEQADLLPSFLGWDGVSMHMNFGAMLADGRVDEAALKEYYRRLKLLGFFWFSNAAMQRGIWAPVSRGLKDRKAWAGYQNIFNYAEIVLNGHEGKGLPSLLELRILDIPINPNYVGLYYLLALLAIRGKIDLEQSFEEYVDTVRHASQFGLRGTVVTHGGGKAQGRDVLRQLVEENAGLLASLNIDEAVREALDAQIHNGFTSRDFIYAVFGAFDEDAARKHLNRIFELGNRSPEKTFSQVLAEYVSQLEDKEARSIFEALSFFITHRKSPFSSVDISGVRLERRAQGRLEVARLQIHDTQNIGILLDNEFMLKKLSRNADGRLEFIFERATDLSEVGVFTYGQNVLPAPAAVVGAREGMAAQARAEGVDVSGVRRPKLVVIVQKRTEKGFVPCSEPATYVDFMKERAAEVGVDIEVLDVQDLNEMKARINPVTGRNGLEEYFGQAKREGWVVLNRAYEMSEPSEIYPQEFLSLPGEVWDIQSTNGVNSLYFETISPSKAKVLELLRVSGVEAVTQHLPESRLRLKKAELRDAVTVMLKKHSAVMIKPDLGSKGQGIVYVDRSMLEFNPATGRSALDEIIEGLTPDRVSSIYGLVGYNVEQAIDLAENAEGRRFIGRWIVQRDIHGGWVVSQRLIRTVAEKGSLITDANTEGEDTIENLWREGILTEGQIAEADAMAVGVMDILCAYMRSQIGAEGAANVGVDFAFAKDGRIYFLETNERPYQAPTNLTPILPFRMDNIRRIVDSASYESTRLQIERARKGASDVVESSVSVGRQQGRVAQERGFKKPHVSTAAEMARGGVGQDAFSSPVTNASLLEEFITSLDLKAPDVVHIKGLLHKYQVLKAMNPQDQAAQALVIGQNFYPSALLTEEQRSTLLGAVDYDDIAADASNRLAASDVVITFNPMDGGLGTSVKRERYLEETLSRPKDDPKTGRARLGAKATDLYFTFEIEGKDAQGNPKTFEKTVSIAEIKLLRVLKDAILYRQAIFQPLVNDDSAPSYRKLLDSTYLPDTLDESIPQGSRRTYREAMQQLNVGLTKGEDEMLFQKDLPIIDIETGLLTTKFTAPGGHGQWGVRLLFEALNFHQPFASAQDHAPRTYIRAFYNGDGAANFPDANIIGWMAKNKVALVMISTTKAGLDKKGGQIGIQVISDPSTPSGLGPQGPGVTIRAQMLELAQAKKVSKEHEQLFYAIGLNGTPAVPGLDPLGRQASSLTNEPGAQCFNTNIALINYTVLAPILREVASLENVEYEGEILSGHDLVERIVSPDLIENVKEKKDSKKYTQLEGAIGSSLLNLNAFFATTKDERIKDILQRHGQEKLLRVVNVDTEKRTRFFTPVKTAFDFWFQAYSDYYRFDAKNWTLQDATEGQVPPTINLASYKRDPATGELKLDNKGKPEDDAYYGDVQNVIDSFGTTSTRHLDTLNITGHVRLNNVILKNTVTITSDYAGIFDLNPPKPRPAFGTFGQTGDDLLVLDNTTVTINRAGEVSVSSAARGVSSGAKNNTTLLSPGRKIKVSRSQANSVKKAGRLFSYVTAAEWIQSLWEHKDKTADQPIQYRANGTLIVAGKTCPWLGKAADHEHAKKLLTALQMCGLLRFAREKRPGSRTIRVGYYMTPEFANASREQIDAVCRIPRFHEKSLSLVSGRRGASRETLKTIREQVKAILPPVVKLEVTPGVFRNYMRVELTGASRQAFGFVMRRLAAETERFVGEIEQWLEQCGGDGIKQRVSSFEESISVENIASLWSATEALSSMPIYFISTAEHYLRNKVTSLGGFVNWCLSDKESKRQLGIESLRDAIGSFRDVVGLFRSAADAATMLVHHEVNTIDIEMSLASLKKMEVVSISSPALKGKVSWQVEICDNRNKIIADPTAPAVRTYRGRLTDTDSPVMSETSSRSGYSAFEAGYLVSRGLSDPCGLTGAGVVGENLSSPANFTKAIAEMFRHHKGTFRAADLDAGDGAFVVRLGKFLRNLSLFEQVKVAGVEPLSFCIDKALVAEAARNGDRVLYGEAQDHIASASIDLVTINNITRDDELLAQAFRILKPSGLLVVTVEQMDVESGKVGNLKAKLAAAGYRVETLEVSGYPYPVGSPYLIGAILAAHKVTVSSPTIALNMRCYTIPFPFPDMMRGRGVNRPEWLESYVLAGVLLRLNRNEDHLIAVNDIYNAAEAAFRDHMLPFDQGRLVDLLEGLRRRGLVRNAANGAFDIETITGTQVVFDLNPRLVATWADDTAYIQHDLKKAAKAGRREFLAAIDMYAQFAQGWSIYPVEANYPVLRAVALMSQRDHEQMVSYLLSRSQWERLPLIDAVLLMLDPQAATVDWLASQAPQLLHRSIYFVAAEISLLAGGLGRVMQYHGTGMHQLGADIICMEPFYRKHRDKTGAVHPLDYTDPHAVPLPVRDLQKLDKTFNTFVQGQYVTFEAYTAVNGIGVLTYLIRDTDGRFVNILYEYGTPDSPASNYEFTEFFTKASLELIRYLELEKKHRLGSGYKAPLVDCNDGQVLPLAAWRKIFYSDASAIMHADVDDNNLLETYEIFKDAVFCGTTHTYRNRVMISDFEYGKRYLKAAGVPDEWLWVFLRDEFGTKIWDFTSAGVRCADVAKAVSAIHGFEMNSRDPGVRLYGVTNGDNRMYSSEFLRAALMKHDIDEYEYLTAEQVAIGKRQAKEDSGFGLKADQMVISYSGRLVAEKAGRFRAFTDANIEAWVKAGIQVVIFGNVQPYEESRRIGQDLEHLQERLSKAGYAGQFIFRGKFNIDDQRRLLAASDIQIQDSDRYTGASEYTEADVSANAGLQMGAPFWEGIIQRQGLAVNRRTQTGNTLIPAATSDRDYRRIVFWANEEFQRGTLSIYQAQSIRLSRYLGALITGAEYLRLWNSAIFNHQKSPAKPRVCGEAAIEDVTLLAYSAEGVKNVARNGDVFSLDADNNEELELTAKIDLAGWDTVNYGKSGIIPFDMVRADLVNDFGIRVPLCLKRRVDSHVEFYTKIPTDLPLPMEGELEVTSGVWKAAKVVKLLLNGNNNTPEPQAEEISSPGVNSTQEDPEKTAGVDDVNQTRAAPQESKVLSSPSLSLPSTSSGLRPSTDSGLRRTSSQSHSSPSLRSGRRPRIETNLDILASVSSPSLQNQCGYQEINKADLVGVLGASFIADKSLNISFVCEHCGVQVSPLHGGFRDHCPHCLWSKHLDNAPGDRANKCKGNLEPIGLMYNGKKGWMILYRCTECGTIKKNKAAADDEPQVLAELSTEPLFISSPSLSLPSAGSIALITGLSGISFDRRASSAGSSNPAVDVAGLPAVKNGLLHPLHMERLMATKDVVNPDDAPLVAISGAAGADFSTLLHAVNPLVSFFICKYPGRFFKTSAPYLQRVLAGEWKPFIQRHLDPEYKDKYFSGYANGAFLNARRSVAAACMFELEALEIDRETIYVDTYLGYPRLSFLWAYPGTANFENYQVTLINADVTRPSEYRSLLESLTFDVYYQRAANEIAAAYYRKESFIRQLYMRMRAGGYFVTDDHLFDPDADRFWDCGKDFPLPLPEIEIPGVGELDQRLSDFLYGDNTAVAEAQRHYGWMLRVRRKPLDAPGSVSFGRERQGGPASVSSGMSSFVKGPGSFMTADGRKVSLVMLIKGEGKEQRIADALEDSIINVEGDFCVVEIEGFARPNGEPQQFVLKHVVTPDILSGWPTAYMTIRRNAERTLFAAGLLRMMLADGNFSGLHIIVPEIRVIQREGGRETFIATEYIEGAQTLVATKLGSNVDASRIARAENNEFLDVYFGLLLYWADAQYLLKDGRLIPFDMETSLAPLFYNDHSYNVHGYPLLSVRYDAYLDAARKIREFIRRNEERVRALIVSTGVADNGELPIDAKPVERVTEQGIWDFIEIQADRLEEAVAQTLARKERVTAIKSFVKRGNAAADRADGVSSAAINRTQEDLQKTAGIGSVNQTRAAPQEPKVLSSPSLSLPSTSSGLRPSTGSGLRRTSSFEEAAHSELEGVKPYVLADSSSPATNASLLEEFITSLDLKAPDVVHIKGLLHKYQVLKAMNPQDQAAQALVIGQNFYPSALLTEEQRSTLLGAVDYDDIAADASNRLAASDVVITFNPMDGGLGTSVKRERYLEETLSRPKDDPKTGRARLGAKATDLYFTFEIEGKDAQGNPKTFEKTVSIAEIKLLRVLKDAILYRQAIFQPLVNDDSAPSYRKLLDSTYLPDTLDESIPQGSRRTYREAMQQLNVGLTKGEDEMLFQKDLPIIDIETGLLTTKFTAPGGHGQWGVRLLFEALNFHQPFASAQDHAPRTYIRAFYNGDGAANFPDANIIGWMAKNKVALVMISTTKAGLDKKGGQIGIQVISDPSTPSGLGPQGPGVTIRAQMLELAQAKKVSKEHEQLFYAIGLAGTPAVPGLDPLGRQASSLTNEPGAQCFNTNIALINYTVLAPILREVASLENVEYEGEILSGHDLVERIVSPDLIENVKEKKDSKKYTQLEGAIGSSLLNLNAFFATTKDERIKDILQRHGQEKLLRVVNVDTEKRTRFFTPVKTAFDFWFQAYSDYYRFDAKNWTLQDATENQVPPTINLSSYKRTQETGDLELDDKGRPQDDGFYADVQNVIDSFGTTSTRHLDTLNITGRIRLNNVILKNTVTITSDYAGIFDLNSLKPRPAFGTFGQTGDDLLVLDNTAITINRAGEVSVSSAARGVSSGAKNQAADVVNILRTTAKARSLTDEEIRRSVSLVKENFFNKDFSQGKNWSLAVNVLIKCARINPRLVRDTLRYEFTQPKHTLEEYQEQYRAVLGKEEADRIFSDIRESVAVLKRNNKNKIVVFNATFSGGGVAEMMLTMGSILKLLGIEMEWHIIYPRAPEFYTVTKTIHNILQGKESVLEPHQLDLLDTVNFDNARIFESVFTDETVGAVFFEDPQVNSMVKAAVHIRQTMFSAKMPMYFRFHIDLSGIRQRNPSAMDVWARFVESLRLLDSVSDAILAQPFSIPSEANDMRAPIYSQPPGIDILAEKNRVIPGGEARDIIASEITDVFGRKVDFSRPVIVSGARFDYWKGLTIVVRAFEKLVAENVVPGDVALLIFGNYASDDPEGTAYYELLRSLMEKSPCKDRMYLVANPHGRQVGSLYRLAAHHKMPYIALSLREGYNLMVDEAVRQGTLVVTSNIGGLRRFRDGRDALVVDILDSIEDLRDIDWIQPGGMLFDDLAERLAEKLKTMFVLPVQESVFQYKKIQGEATKKVFRASLITMMRDYLKRPADYWKQGESGLLQDEEVSSPAADEKEFLRQMGRSFPGLELLRYRSGVNVVVVDGAVHSVRAAVFPEKTGILNLNPENIFELETFAPGKATSFRGPYLAIHGNVVNGRLVVEKTEINIAELINALAGRFSIDRLLLLSCNIGAGRLDPLAIPTVYSREGGVSRGSDHRDVLLNKLFTDKGSWVVKYGEESREYAGDAHRAMAAGTGALLSSPCSKARKQALRPWKEIEGVFETHYHGRVFPTGESYFGHVLRVLEKVREYCEDEDVQLAALAHKTEAAHLKDILREAGCDKDRIQRITAHVKVLLAATSLPSSIDYRNKYAIQNRIDLILKVASTYSLRILVLADKFASIAAYSGEKDLLDQIGLIYAPMAERLGLILLAAELREEVFKHSQPQHYFITEAEILTALRVSSRNEAEEYLRALGMTIVNYLHEKIDGRVAVYERVKKAFSTWLKVHFRSDKYPSIAGLGDLFGISIVVEDEADVYAVMSCLGAFPPDSELRLAGRSFVPADPANAVDTKKLDMGPGRPMLFRYHLDLVDDRGLKYEIQVCSEEVFREMFLGHIAHWSFKITQLPFRRLKTQKFNAVDLSGTRDIKDISAKISEYLEPYVFVNVLDTRNAAGKRPLAINTMRWPAGTTLEKLAAELSQEGSKNKMIVSPFGSYVADSQNHMVLETYFVRGAHYILRDGDLVVISDKGATRGVSIPLNSTVLKSAGGTSGSAQGAMEGLTGDDLFDENGLTSPAVRAVVFAGVSGSGKSTYIERLLEERAESFVYPRLTTTRPARHGETPDRYRVFVHEKSFLQHLHRFHLVRQRHGHWYGIAAGELEEAEQADKAVLFDTSSYESLTMLKAEFSSVHAALVLPVARRQLSRMTEKELRHVLSSRMAHRKMNGQELDIRLAEAVTNLRIFEERIGEFDRVLENGAPQDKDRNFAILASWLSDVSSPAIKARPVFVDAKKKALSSPALCASDPASIRQAIRAAKEEGRGVLLQGAVQDWGKAHRKDINKYHQALILTSGIQIELPLGLGSVDAYRSLRSSNVVLIDPQKPALPELRNAWYEPATGELYLFSSIQEGADADLVLRLMEGVATGIARQRILLGGAEWNDSVVETLQHHFAAGLEIQIKRQRDSWPSAARHHFAFITPEYFDVAKIGGLSDATSGLARQLAGQGHEVSVFTFKYASHPVGNIGLKTIGNVWVDFGDRPAVVVTVSKAEIGKLTIYTLEHDYVTRRPYMDDIGLQQAVVLSRGALEAMMAFGIRPDIINAHDWQAALSMAYMQAHPRYREYFASARRIYTIHNISHQGRYEKRDYFRTGLPWSEFAGGALEFYGGFNLVKAGIVYAQKVNTVSPSHAFELLTKAGGHGLDGVLRAKGFDFCGILNGVDSEVFDPSRDPFIAQHYDADSAMQAKVVNKMDMQRRLGLTVDPRAIVIALVARLDNQKGVELLGDRIRKFLADHPDVQVVIGGPEYDRKAVDKIRNLPWEAIGRGRAYVLPAYIHEDQAHRIFAGADIFLVPSFHEPCGLTQMIACRYGAIPVVRRVGGLADTIENYDEMTGTGNGFVFDNYNDEELFREIQRAVHLRRKPDLWQRIVRQAMHKDFSWGLSAINYSLLYEDALVFFGKDVSSPAQAGNSSLRTEVHDIKNKVVAATGLVNLLKRVGERSGVSDEAVSSLQAVFENGAKTEAVFAKYLSGQTSDEEILEYLRENIQRFVSMEQEFARWHEAAGDLPAFASREQAIAGVRESLEATVARTKTLLYTWLGRSMTYDQLRTFLAGTVDYFGSVYSVESLRLEIAPNVPVNGVFTYFDMARTHLEELLYNAWKYGDKKQITVRAAVAKGNELEIRVINTGRPLSRRELKDIFVSGSRCEGTEGIEGYGLGLPAMRQDIEVVGGRILAYSHPQQDLVSIGFRLPLNGPVAGLPFVLNRFPGRLIVVCGLAGSGRRTLARLLAAHLGYRYFNPGFFMRVVFYHMMQERPDISLDDEQGMAAYMRQFLEAGRINIWEEPLAIDGTSTLAKDAEGISLRNCIKRAIDGNPEMLEAFDRFANMRPVCNSLNDYLMGMVDRLDGEYNGLVVRSTDPWPGAFNVMLLAATAIRAGRLRQDAARIQDRDARTLRSDYGRQLLLRLSGAALSSQKLMPRKLAGRVMDALRRQAVRSSDDISSPAEALEKDAAWHYVGRNIRQEYRQDIEKRFERHFRNERLSRYLLWSVIVAGAAVFFAIHPAAPALYFVIGGFLFQALMSFGWERALDNNVAEFLDTHSQTLWLSWPKGAKKTFIHKLYSTDWRTYSRRGRQKFYDDLLLTLDLAGNLKIIQARHVLPALVHNGLERLFISRVYLVYEPASRFDVAYDGGYLVVNVHHYEGQKAHDSLNAMRADIFYRTILKQQLEELSSLSKQEAEGGALLEDRYFRAAAFDRSRLTSSDRQRINGRLAKLLAQRAALILSYNHRVCEAAIQKDIERALGVLRGRPAQDVVLEIAAIFALVETTQYTTQEKSLVDLFALMPQSDEAVSYFMALREEFKKFLASIEIVNDARVHLVTQEEFDGHHPAAAGAKRYVSRSGDFWIVASAQQAVNDAEIAGGLALKRYHDIQQDMPGRSQKAVELLRHDPAARVALRSLLALLGSSVPDKRVSDMFQGSNGRFDNISLQGAEELFMFVTPEEAVCLINKFIASLPQDGRQEYAGAFTAKFVPGRLLMFDVFAVDSEANKNIQYTLRGALVLLKTGKVAVLFQGAPWTRDRVRFMKQHGWLSYDPVDDRYHDYAKVTLNEQCLVAQNLLAGGMPADTPVTLLAQDEDGKLFTEQGRSLADVARDGLRMDHLYPLQPHPDFVPFSMAFALGLLLSHYNRLTYLQERGIGMSALEENFLGQCRRLSSLQKILDIFPSQAERDVRRVKILNSPQDVSGSSLSSPALMRQNRSALFSLISYSPLLSEKEYIRISTVSQHREVAPCTAYRILKSSALSRQPEVFTSQPGMPNVFTNTASTSRRKAGWRERRLPENGLNSPMTLPVAWSPRSSVRFWSKETPWSGSGFICPEKKALSPISPRQYIGSSPAQQLGVVAGLAAHRVHGPDFVELSSPSARADADGLDVSSPIARFTKAWQALQRKKDRAAARILKKMRRSGDLQAFWELKDSPLYVAQMIPAAGAKRVTMLTLQGSIYLSSMFGDIRAAEDSLGIARRFKCGPDDELSPGEFACRELVTNVWKHANYGYFAFSFLPYRQGLRFVCFDRGPGIAEIGRALTSGYSTLGTFGLGLNYLSQDVLASFRNFSIQSIPQKGTLVFVEEPAGRGIEALKEEAAGADGDDEYLPFSSATAIKKDFSSPALNETLRPDLKVSLRGDQAIRAEIDRLFETMKSRIGTLAQQGMRLDENKVFFFAPEIDEIGALPGFSIKTRAHELPWKDCSAYLYHIRPELGMLAGPIERISEYGFVEVGIHDRRPGDIVIYGAAGEAKHFGVVAEDGRVESKFNIYHVYIHPPLAVPSSYGTPHFYRKHEDISSPVVQVRAGPQAEFFFRTLLARLKEAACPFIYFDNNIGLTIVAGIPFFDPRAGAPYCNWGRDTMISLPALTLSTGHPEMFRQIFKNYVRFVKDGLMPNFIGDGANPRYNSVDATFWMFRALGIYLKETRDYAFLDTKVQRKTGEGPETILQIIAGVFDALKNGIACEDRCGNRVQTVRVRMDADGLITAGDENMNLTWMDAQPEDGSGKPATSRHGKAVEINALWHDALVMMADILEERGDAQKSGSYRALAGRVHQSFQKFWNAENQCLYDVIDGDPLQAAQVRPNQVFGLHLLGKDKARLALQTVRNELLTPFGLRTLSPKDPAYRSEHRDEDYIHSYHQGTVWPWLMMGFVQASMYAVGQDETRRILEEAGWFDSLEAFLNDDTTRHSVPEILNGCCERPGHWNRKGCPAQAWSVAAAIDSVFTLFEYLQGTNISRVSKEAEAGIWYQVVVKDFKPQDESGSRIEYITKQGLPRLAAAGIKTIWLMGAWQNVGGNEPFAILDPVKVESSYGTLEELQEFLAEAKRLGIVVLDCYIPNHVSKNSPLVSEHPDWFIWENGQLVDATDLRWAWGWASCAQFDFLNPEVVAYLFRVARYKLSLGFGGLRLDAPLGLLKARMKHNWYQGREAEVDRMFPQEFWAMLISDLRRDYPDAVFLAESLGSAADRITLEACGIDFTMDIEISTKLFDVLQGWKPPWDFKGYLEYRLFCSFMNPAVHAFDNHDIRDPEHMDLSVGMEKLRTLDADKIRYFALLMSTLPGPFILFNGQLEAVLGYSYRSCQISSINWGSVDESMQEYFRRIAGFANQPILRHGAAYAAFPMAGGGHPEVVAYVRTYGDEKVLVAARIGLSGAEGKAWARIDVSEFLVPGVEQYEVADTFSGAHYPVVSRETLERDGMTVGLSAKEIQVLSLRPVSVSSPAAPASPVRTDDKGRFVFKGVRYNVSTRFAHKTLSAEKTGEDLVHVFDAGVLIAKLYPSTETCQLLSLRRTADDKGRFAYGRKRLNLGMSFAGVSLTLLPLEDNWQNGFDVSCGGRRVARYDALSDRFMIYASLSRQADDKGRFGYERRRFNLGASFGNASLELAPSRGGWEKGFRVYHEGRAVALYNAARDFFWVLVPLDRRTDDKGRFGYEGRRYNLGTPWANTDIQVVMRRDGGFSVFAAGAKIAELEDLERASEESESSPAENNETLRPDLKVSDLRHIPADEAIASSLSSPSLPSPQEICAGLREFVVLADAELRSSKLFTAVKSFVASFELPVRDLLVIGLVGVLSVLLYIYRNQLMHMAYRDGMTSVLYNRRYLDMKISQADMPGRHFRKDDEAAILMIDLDHLKEWNTEFGHAAADKVILAVSRVLVDVVRSDDVVARYGGDEFTVILKRADAEVGRKVAQKILAAAREISFAHPKTGVRRHVTLSIGVAEYPEDGATVLDVLKAADQAVYVSKNRGRNRVTVFGEHSSRQLELPFMKDFDEGASNGLSSPAGMVHLRPGQECPVNLAHSEISSASIGQDQVMLSWKLNGSLCDIEENVHGRSGTVMGLRHNVVIRLNDGRAVFVTDDHAHVYAFWWLMFKEGLLRSSHRLLHVDGHADAQMLQAGRARRLDPFDHMSASLAEADDFAMNAAGIEGFIAPLVQRGLIASWHWLYNLNDYRAVRMAFADGKYKGLEGEKAAVEDISFDLLDIDIDVLAGLAPQEAVSHLDVFAAMASRASLITIATSPEFIDQKTAVAYARLLAERILASGGGVAPVSSAAQDIDVTFRSMPGRRFTCIDGACCYFKEAIVPEGIAEALMERDGSEGPFLRDNFAMGILKPDHRNRPGSEDYLVAGYPCRALQIILDHSARTGLTLVSSCTMYGGDRAKICKTFPAKKKCLGPCLFDLFVKGIWGLYYMVPQRLLAEGPISTFGQAISRGAGIFVTQRAHAFLSRKMQEGAARAVSFDGAGREACLFLQPSANPLVGVYRTERNKAVHSWFGRAPSGSPLSSPAAAARRWLIFDADDTLYPHDSPLAEAYAAERFACIASLSPQIDSRLDAEARIAAAASLFSATEKALSLRQDGRLVSKSRVLKELGVTLAAWEEWKDAHVRPGDYLKPDFDLARILKDLSFEYRFALWTNNNRAQSEAILGALGIAAYFDHQDIFCTSEHRTRKPDPGLLRHVIKEALKTRPGRCIVVGDSIKTDIEPALELGASAVHVHPQGIETDRPWNGNVRVVKSIYELEEAIEDLRAVSGPTANETLRPDLKVSLEDNFSSPSLASNGIEIDVVHLGSIRSESRRRTLYASMADINKAINGHEGNWHEEFDDVLQYHFFKSQGIGRYLTFASIGRRMLGYCFYDDHELDYLAVREEYRHQHLGWEIMRQALKDLKGRGVNHVFGMLHKDNKPIQDFYARMESEQILPGIKVDFLGTHRENDDYYKYRIRGMRWGFFEDEEEDGSSPAVGRAVPIQVVKIAFPAAWEDTFAALTEKLSRSGLLKTVSFEHAVFDNQPVQRIIYAGGHLDACIDTSLVATAKVAALYGIRAEIMVPLDLVYIGPEDFNGSHQQALALKRRYAEDLLGRLHAVSPQDITVRFYGTTEAMLETIEQVSSPSVTRWAKEKAKELLTQAFEEMGISSEKLQNDPRYGRVYRAVVKYGHEWWGCKDWQGVTFEDGGIVHLVEPHQRAHLVVRMQQGFNPVAFDVRLGDRVFSLLHSSGAPILFPFANRLRVDRKGAARWKDTQGRVWTIPLLTSELLASGLVTKDSDAAVRHGLVRKHPFDIIACGSKDDVYLTGAFRTADYPLIPGLYQGLVLEVTYRLSDGRWTTRTYVRNESDHEIPIGFCQHYDLNVFGAYEKARLTFPGQKLWHARRRLPSGRLLDVKGAFDFRSGRRLGANPAYDHVFYAGEGAPYQAWIDHEEGVRTVVEADSVFKNMVIYTPGAKDFVAVEPQTSSTDALRMDLKAAAEANLIVLKPGEERRWQTSVGLEEAGQISSPSGTRWAKEKAEGLLTEAFKELGTSSEKLQKDPRCGRLYRAVVKHRQEWWGCKDWQAVVEKFGYKPLRRSYDRASFLSELETIIFELRDHSSTVIEKKYSGLYTAFLKNKEVWGFEKWGDAVRAAYTRQLFLRDIQEALAGAGRPSTRVLHKTNPWIYNLFLDEQKRAEMGFGEWNDVVEALGLDPIFRKKTRPEFLEGLALEMKEKATSDTVKLNHYAYFRRHKREIGFSSWSEVLEALRAEEGPKKEARRQFVEETQEELAAGAWKKMETAELEAYVKDIEAKARPFVRFVGLDEVFAILRVHGVSGLSEAASSGKLADINMDFRLRGMDCGLIVKSETRTLYEDMPAFVHTYVEFRAGIKELDEALAPLKARLTEELDKTRKQGGHFHAFNGASYASKGRGRKASRKAPVDEDDLDADETRDISSPAKSSPYRQTILP
Catalytic domain sequence
8565 aa
IYFVAAEISLLAGGLGRVMQYHGTGMHQLGADIICMEPFYRKHRDKTGAVHPLDYTDPHAVPLPVRDLQKLDKTFNTFVQGQYVTFEAYTAVNGIGVLTYLIRDTDGRFVNILYEYGTPDSPASNYEFTEFFTKASLELIRYLELEKKHRLGSGYKAPLVDCNDGQVLPLAAWRKIFYSDASAIMHADVDDNNLLETYEIFKDAVFCGTTHTYRNRVMISDFEYGKRYLKAAGVPDEWLWVFLRDEFGTKIWDFTSAGVRCADVAKAVSAIHGFEMNSRDPGVRLYGVTNGDNRMYSSEFLRAALMKHDIDEYEYLTAEQVAIGKRQAKEDSGFGLKADQMVISYSGRLVAEKAGRFRAFTDANIEAWVKAGIQVVIFGNVQPYEESRRIGQDLEHLQERLSKAGYAGQFIFRGKFNIDDQRRLLAASDIQIQDSDRYTGASEYTEADVSANAGLQMGAPFWEGIIQRQGLAVNRRTQTGNTLIPAATSDRDYRRIVFWANEEFQRGTLSIYQAQSIRLSRYLGALITGAEYLRLWNSAIFNHQKSPAKPRVCGEAAIEDVTLLAYSAEGVKNVARNGDVFSLDADNNEELELTAKIDLAGWDTVNYGTQGIVPFDMVRAELVNDFGIRVPLCIKRRVDSHVEFYTKIPTDLPLPMEGELEVTSGVWKAAKVVKLLINGNNNTPEPQAEEISSPGVNGTQEDLEKTAGVGDVNQTRAAPQQLQVISSPTQNLKDFFSASDIARDALEVHALIILGNDNLETFREALHLYQEGKAKKIITTGGRGRLTESLIKEAARSGFNVAPASEARMIKEIILAMAAQEAIIVKEADILLEEQSSNTPQNFEHAIPLLTQVRREFGLMAGEALRVAYIQTPQQQFRSKATFNVYAEAWQRLNVQGISYTIDWDVEGLSKTEFSEVVVAEMWRIILYAAKGDITPEYRGVKGLNAIPPALWQEVVVLVDTYPSSDSLKNKLRVLASNAGYERVETLQKDLRKTTVNVASEDLNQLIEFVYRDGSISSPSSIADLAKPLVVLSGCILTISLPDIFKSIFSADPIYQITAGAKEFLIYTTILFVISGAIWASDTLIEKIFDKYKSDKISAKSELISRRYATEYATARAKLEGRLGHSLPASQTGLSLDLIDFLNLIQETNILQAVIANWTLIEEYFTENFAQKIIETEYYIGASGPCGEVWGDQQRSSWVAEKIALGRRNLAQAGLQGSVEESYRWSEPNPYGPGKVGHELRQTTGYELIRKVNYDKLKNFVSSLKPSNLQDKLNSIGRDSISSPAQAASRSFGRKLLAISHETQSVSSPASSASKTKSFYQKKVVRGAEFPWIDDILIKSGKYLQDKVKWVGIKNEAASNWIYASTASIHSAVGIGLSSAWSLIYLAKGTYPHFLPELAWGSAPFIALVGPFAIVFSIVSFALALKTFFAKDLTRGGLIHAWASGTLSATAIVYAATLTWYWPILTAIVVGLFLYGYFLEGTSGVTTESWKDTTKEKTEKIKEKYRSQAKQNTEGQRKHQEEAKRRAEERRKAQEEQRRKAEEERRLAEERRRDEIKRQNIETGENWYRFSGRMTVVRAYELFGLEFGVSLDQVKQARNDLMLKFHPDRARNIDKSRATIISRNVNSAFDVIKTWLQDSVSSPALASYFRIDKVLVKMGRYLQGKVDQPFLETSALAVTALGFGAAIFWSLKLLAGAVYPQFLPILALTSIPYLSVVGPVATIYLVLSLLTSPKFLFDFKAPKISFIKDFAVNLIHIKFIAAVKVLGRFLGGILTVVGIKELTRGELRHAWVSGTFGSAAIVYITTLAWYWPILTAIVVGLFLYGYFLGTTTQTTDRGPAPSDQKEDKKESNKEEESAPKTQKKESAPTIGTEIELTLTERQGDSASKDAVERQRVRGGSKKGQGRHWAPGSRRPVGYAMLKDAVGEHNGDSGIVFDHSVAVEANTGHRSISEITDEVRTFAEQTLKILALIEKIMVAHPEQADLLPSFLGWDGVSMHMNFGAMLADGRVDEAALKEYYRRLKLLGFFWFSNAAMQRGIWAPVSRGLKDRKAWAGYQNIFNYAEIVLNGHEGKGLPSLLELRILDIPINPNYVGLYYLLALLAIRGKIDLEQSFEEYVDTVRHASQFGLRGTVVTHGGGKAQGRDVLRQLVEENAGLLASLNIDEAVREALDAQIHNGFTSRDFIYAVFGAFDEDAARKHLNRIFELGNRSPEKTFSQVLAEYVSQLEDKEARSIFEALSFFITHRKSPFSSVDISGVRLERRAQGRLEVARLQIHDTQNIGILLDNEFMLKKLSRNADGRLEFIFERATDLSEVGVFTYGQNVLPAPAAVVGAREGMAAQARAEGVDVSGVRRPKLVVIVQKRTEKGFVPCSEPATYVDFMKERAAEVGVDIEVLDVQDLNEMKARINPVTGRNGLEEYFGQAKREGWVVLNRAYEMSEPSEIYPQEFLSLPGEVWDIQSTNGVNSLYFETISPSKAKVLELLRVSGVEAVTQHLPESRLRLKKAELRDAVTVMLKKHSAVMIKPDLGSKGQGIVYVDRSMLEFNPATGRSALDEIIEGLTPDRVSSIYGLVGYNVEQAIDLAENAEGRRFIGRWIVQRDIHGGWVVSQRLIRTVAEKGSLITDANTEGEDTIENLWREGILTEGQIAEADAMAVGVMDILCAYMRSQIGAEGAANVGVDFAFAKDGRIYFLETNERPYQAPTNLTPILPFRMDNIRRIVDSASYESTRLQIERARKGASDVVESSVSVGRQQGRVAQERGFKKPHVSTAAEMARGGVGQDAFSSPVTNASLLEEFITSLDLKAPDVVHIKGLLHKYQVLKAMNPQDQAAQALVIGQNFYPSALLTEEQRSTLLGAVDYDDIAADASNRLAASDVVITFNPMDGGLGTSVKRERYLEETLSRPKDDPKTGRARLGAKATDLYFTFEIEGKDAQGNPKTFEKTVSIAEIKLLRVLKDAILYRQAIFQPLVNDDSAPSYRKLLDSTYLPDTLDESIPQGSRRTYREAMQQLNVGLTKGEDEMLFQKDLPIIDIETGLLTTKFTAPGGHGQWGVRLLFEALNFHQPFASAQDHAPRTYIRAFYNGDGAANFPDANIIGWMAKNKVALVMISTTKAGLDKKGGQIGIQVISDPSTPSGLGPQGPGVTIRAQMLELAQAKKVSKEHEQLFYAIGLNGTPAVPGLDPLGRQASSLTNEPGAQCFNTNIALINYTVLAPILREVASLENVEYEGEILSGHDLVERIVSPDLIENVKEKKDSKKYTQLEGAIGSSLLNLNAFFATTKDERIKDILQRHGQEKLLRVVNVDTEKRTRFFTPVKTAFDFWFQAYSDYYRFDAKNWTLQDATEGQVPPTINLASYKRDPATGELKLDNKGKPEDDAYYGDVQNVIDSFGTTSTRHLDTLNITGHVRLNNVILKNTVTITSDYAGIFDLNPPKPRPAFGTFGQTGDDLLVLDNTTVTINRAGEVSVSSAARGVSSGAKNNTTLLSPGRKIKVSRSQANSVKKAGRLFSYVTAAEWIQSLWEHKDKTADQPIQYRANGTLIVAGKTCPWLGKAADHEHAKKLLTALQMCGLLRFAREKRPGSRTIRVGYYMTPEFANASREQIDAVCRIPRFHEKSLSLVSGRRGASRETLKTIREQVKAILPPVVKLEVTPGVFRNYMRVELTGASRQAFGFVMRRLAAETERFVGEIEQWLEQCGGDGIKQRVSSFEESISVENIASLWSATEALSSMPIYFISTAEHYLRNKVTSLGGFVNWCLSDKESKRQLGIESLRDAIGSFRDVVGLFRSAADAATMLVHHEVNTIDIEMSLASLKKMEVVSISSPALKGKVSWQVEICDNRNKIIADPTAPAVRTYRGRLTDTDSPVMSETSSRSGYSAFEAGYLVSRGLSDPCGLTGAGVVGENLSSPANFTKAIAEMFRHHKGTFRAADLDAGDGAFVVRLGKFLRNLSLFEQVKVAGVEPLSFCIDKALVAEAARNGDRVLYGEAQDHIASASIDLVTINNITRDDELLAQAFRILKPSGLLVVTVEQMDVESGKVGNLKAKLAAAGYRVETLEVSGYPYPVGSPYLIGAILAAHKVTVSSPTIALNMRCYTIPFPFPDMMRGRGVNRPEWLESYVLAGVLLRLNRNEDHLIAVNDIYNAAEAAFRDHMLPFDQGRLVDLLEGLRRRGLVRNAANGAFDIETITGTQVVFDLNPRLVATWADDTAYIQHDLKKAAKAGRREFLAAIDMYAQFAQGWSIYPVEANYPVLRAVALMSQRDHEQMVSYLLSRSQWERLPLIDAVLLMLDPQAATVDWLASQAPQLLHRSIYFVAAEISLLAGGLGRVMQYHGTGMHQLGADIICMEPFYRKHRDKTGAVHPLDYTDPHAVPLPVRDLQKLDKTFNTFVQGQYVTFEAYTAVNGIGVLTYLIRDTDGRFVNILYEYGTPDSPASNYEFTEFFTKASLELIRYLELEKKHRLGSGYKAPLVDCNDGQVLPLAAWRKIFYSDASAIMHADVDDNNLLETYEIFKDAVFCGTTHTYRNRVMISDFEYGKRYLKAAGVPDEWLWVFLRDEFGTKIWDFTSAGVRCADVAKAVSAIHGFEMNSRDPGVRLYGVTNGDNRMYSSEFLRAALMKHDIDEYEYLTAEQVAIGKRQAKEDSGFGLKADQMVISYSGRLVAEKAGRFRAFTDANIEAWVKAGIQVVIFGNVQPYEESRRIGQDLEHLQERLSKAGYAGQFIFRGKFNIDDQRRLLAASDIQIQDSDRYTGASEYTEADVSANAGLQMGAPFWEGIIQRQGLAVNRRTQTGNTLIPAATSDRDYRRIVFWANEEFQRGTLSIYQAQSIRLSRYLGALITGAEYLRLWNSAIFNHQKSPAKPRVCGEAAIEDVTLLAYSAEGVKNVARNGDVFSLDADNNEELELTAKIDLAGWDTVNYGKSGIIPFDMVRADLVNDFGIRVPLCLKRRVDSHVEFYTKIPTDLPLPMEGELEVTSGVWKAAKVVKLLLNGNNNTPEPQAEEISSPGVNSTQEDPEKTAGVDDVNQTRAAPQESKVLSSPSLSLPSTSSGLRPSTDSGLRRTSSQSHSSPSLRSGRRPRIETNLDILASVSSPSLQNQCGYQEINKADLVGVLGASFIADKSLNISFVCEHCGVQVSPLHGGFRDHCPHCLWSKHLDNAPGDRANKCKGNLEPIGLMYNGKKGWMILYRCTECGTIKKNKAAADDEPQVLAELSTEPLFISSPSLSLPSAGSIALITGLSGISFDRRASSAGSSNPAVDVAGLPAVKNGLLHPLHMERLMATKDVVNPDDAPLVAISGAAGADFSTLLHAVNPLVSFFICKYPGRFFKTSAPYLQRVLAGEWKPFIQRHLDPEYKDKYFSGYANGAFLNARRSVAAACMFELEALEIDRETIYVDTYLGYPRLSFLWAYPGTANFENYQVTLINADVTRPSEYRSLLESLTFDVYYQRAANEIAAAYYRKESFIRQLYMRMRAGGYFVTDDHLFDPDADRFWDCGKDFPLPLPEIEIPGVGELDQRLSDFLYGDNTAVAEAQRHYGWMLRVRRKPLDAPGSVSFGRERQGGPASVSSGMSSFVKGPGSFMTADGRKVSLVMLIKGEGKEQRIADALEDSIINVEGDFCVVEIEGFARPNGEPQQFVLKHVVTPDILSGWPTAYMTIRRNAERTLFAAGLLRMMLADGNFSGLHIIVPEIRVIQREGGRETFIATEYIEGAQTLVATKLGSNVDASRIARAENNEFLDVYFGLLLYWADAQYLLKDGRLIPFDMETSLAPLFYNDHSYNVHGYPLLSVRYDAYLDAARKIREFIRRNEERVRALIVSTGVADNGELPIDAKPVERVTEQGIWDFIEIQADRLEEAVAQTLARKERVTAIKSFVKRGNAAADRADGVSSAAINRTQEDLQKTAGIGSVNQTRAAPQEPKVLSSPSLSLPSTSSGLRPSTGSGLRRTSSFEEAAHSELEGVKPYVLADSSSPATNASLLEEFITSLDLKAPDVVHIKGLLHKYQVLKAMNPQDQAAQALVIGQNFYPSALLTEEQRSTLLGAVDYDDIAADASNRLAASDVVITFNPMDGGLGTSVKRERYLEETLSRPKDDPKTGRARLGAKATDLYFTFEIEGKDAQGNPKTFEKTVSIAEIKLLRVLKDAILYRQAIFQPLVNDDSAPSYRKLLDSTYLPDTLDESIPQGSRRTYREAMQQLNVGLTKGEDEMLFQKDLPIIDIETGLLTTKFTAPGGHGQWGVRLLFEALNFHQPFASAQDHAPRTYIRAFYNGDGAANFPDANIIGWMAKNKVALVMISTTKAGLDKKGGQIGIQVISDPSTPSGLGPQGPGVTIRAQMLELAQAKKVSKEHEQLFYAIGLAGTPAVPGLDPLGRQASSLTNEPGAQCFNTNIALINYTVLAPILREVASLENVEYEGEILSGHDLVERIVSPDLIENVKEKKDSKKYTQLEGAIGSSLLNLNAFFATTKDERIKDILQRHGQEKLLRVVNVDTEKRTRFFTPVKTAFDFWFQAYSDYYRFDAKNWTLQDATENQVPPTINLSSYKRTQETGDLELDDKGRPQDDGFYADVQNVIDSFGTTSTRHLDTLNITGRIRLNNVILKNTVTITSDYAGIFDLNSLKPRPAFGTFGQTGDDLLVLDNTAITINRAGEVSVSSAARGVSSGAKNQAADVVNILRTTAKARSLTDEEIRRSVSLVKENFFNKDFSQGKNWSLAVNVLIKCARINPRLVRDTLRYEFTQPKHTLEEYQEQYRAVLGKEEADRIFSDIRESVAVLKRNNKNKIVVFNATFSGGGVAEMMLTMGSILKLLGIEMEWHIIYPRAPEFYTVTKTIHNILQGKESVLEPHQLDLLDTVNFDNARIFESVFTDETVGAVFFEDPQVNSMVKAAVHIRQTMFSAKMPMYFRFHIDLSGIRQRNPSAMDVWARFVESLRLLDSVSDAILAQPFSIPSEANDMRAPIYSQPPGIDILAEKNRVIPGGEARDIIASEITDVFGRKVDFSRPVIVSGARFDYWKGLTIVVRAFEKLVAENVVPGDVALLIFGNYASDDPEGTAYYELLRSLMEKSPCKDRMYLVANPHGRQVGSLYRLAAHHKMPYIALSLREGYNLMVDEAVRQGTLVVTSNIGGLRRFRDGRDALVVDILDSIEDLRDIDWIQPGGMLFDDLAERLAEKLKTMFVLPVQESVFQYKKIQGEATKKVFRASLITMMRDYLKRPADYWKQGESGLLQDEEVSSPAADEKEFLRQMGRSFPGLELLRYRSGVNVVVVDGAVHSVRAAVFPEKTGILNLNPENIFELETFAPGKATSFRGPYLAIHGNVVNGRLVVEKTEINIAELINALAGRFSIDRLLLLSCNIGAGRLDPLAIPTVYSREGGVSRGSDHRDVLLNKLFTDKGSWVVKYGEESREYAGDAHRAMAAGTGALLSSPCSKARKQALRPWKEIEGVFETHYHGRVFPTGESYFGHVLRVLEKVREYCEDEDVQLAALAHKTEAAHLKDILREAGCDKDRIQRITAHVKVLLAATSLPSSIDYRNKYAIQNRIDLILKVASTYSLRILVLADKFASIAAYSGEKDLLDQIGLIYAPMAERLGLILLAAELREEVFKHSQPQHYFITEAEILTALRVSSRNEAEEYLRALGMTIVNYLHEKIDGRVAVYERVKKAFSTWLKVHFRSDKYPSIAGLGDLFGISIVVEDEADVYAVMSCLGAFPPDSELRLAGRSFVPADPANAVDTKKLDMGPGRPMLFRYHLDLVDDRGLKYEIQVCSEEVFREMFLGHIAHWSFKITQLPFRRLKTQKFNAVDLSGTRDIKDISAKISEYLEPYVFVNVLDTRNAAGKRPLAINTMRWPAGTTLEKLAAELSQEGSKNKMIVSPFGSYVADSQNHMVLETYFVRGAHYILRDGDLVVISDKGATRGVSIPLNSTVLKSAGGTSGSAQGAMEGLTGDDLFDENGLTSPAVRAVVFAGVSGSGKSTYIERLLEERAESFVYPRLTTTRPARHGETPDRYRVFVHEKSFLQHLHRFHLVRQRHGHWYGIAAGELEEAEQADKAVLFDTSSYESLTMLKAEFSSVHAALVLPVARRQLSRMTEKELRHVLSSRMAHRKMNGQELDIRLAEAVTNLRIFEERIGEFDRVLENGAPQDKDRNFAILASWLSDVSSPAIKARPVFVDAKKKALSSPALCASDPASIRQAIRAAKEEGRGVLLQGAVQDWGKAHRKDINKYHQALILTSGIQIELPLGLGSVDAYRSLRSSNVVLIDPQKPALPELRNAWYEPATGELYLFSSIQEGADADLVLRLMEGVATGIARQRILLGGAEWNDSVVETLQHHFAAGLEIQIKRQRDSWPSAARHHFAFITPEYFDVAKIGGLSDATSGLARQLAGQGHEVSVFTFKYASHPVGNIGLKTIGNVWVDFGDRPAVVVTVSKAEIGKLTIYTLEHDYVTRRPYMDDIGLQQAVVLSRGALEAMMAFGIRPDIINAHDWQAALSMAYMQAHPRYREYFASARRIYTIHNISHQGRYEKRDYFRTGLPWSEFAGGALEFYGGFNLVKAGIVYAQKVNTVSPSHAFELLTKAGGHGLDGVLR
