CAZy Glycosyltransferase Family 4
69 curated protein records across 37 source species. Click a gene symbol to open the full record, which carries the complete set of curated fields including full-length and catalytic-domain sequences. For the authoritative family definition, sequence-based classification and literature, see the CAZy GT4 page.
69Records
35Model organism
34Other organisms
37Species
15With PDB entries
Source dataset notes for GT4:
- GT4 — 69 entries (all organisms) · 35 model organisms listed at the top below.
Family members
| Gene symbol | Species | Domain | UniProt | Gene ID | Ann. | Enzyme function | Fold | Mechanism | Donor | PDB |
|---|---|---|---|---|---|---|---|---|---|---|
| ALG11 | Homo sapiens | Eukaryota | Q2TAA5 | 440138 | 5 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) | GT-B | Retaining | 2 GDP-alpha-D-mannose | — |
| ALG2 | Homo sapiens | Eukaryota | Q9H553 | 85365 | 5 | Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132; 2.4.1.257) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| PIGA | Homo sapiens | Eukaryota | P37287 | 5277 | 5 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | — |
| QTMAN | Homo sapiens | Eukaryota | Q4AE62 | 79712 | 5 | tRNA-queuosine alpha-mannosyltransferase (EC 2.4.1.110) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| ALG11 | Arabidopsis thaliana | Eukaryota | Q9XEE9 | 818610 | 5 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) | GT-B | Retaining | 2 GDP-alpha-D-mannose | — |
| DGD1 | Arabidopsis thaliana | Eukaryota | Q9S7D1 | 820339 | 5 | Digalactosyldiacylglycerol synthase 1, chloroplastic (EC 2.4.1.241) | GT-B | Retaining | UDP-alpha-D-galactose | — |
| DGD2 | Arabidopsis thaliana | Eukaryota | Q8W1S1 | 827960 | 5 | Digalactosyldiacylglycerol synthase 2, chloroplastic (EC 2.4.1.241) | GT-B | Retaining | UDP-alpha-D-galactose | 2L7C, 8P6S |
| PIGA | Arabidopsis thaliana | Eukaryota | Q94BX4 | 823646 | 5 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | — |
| SPS1 | Arabidopsis thaliana | Eukaryota | Q94BT0 | 832150 | 5 | Sucrose-phosphate synthase 1 (EC 2.4.1.14) | GT-B | Retaining | UDP-alpha-D-glucose | — |
| SPS2 | Arabidopsis thaliana | Eukaryota | Q9FY54 | 830979 | 5 | Probable sucrose-phosphate synthase 2 (EC 2.4.1.14) | GT-B | Retaining | UDP-alpha-D-glucose | — |
| SPS3 | Arabidopsis thaliana | Eukaryota | Q8RY24 | 839382 | 4 | Probable sucrose-phosphate synthase 3 (EC 2.4.1.14) | GT-B | Retaining | UDP-alpha-D-glucose | — |
| SPS4 | Arabidopsis thaliana | Eukaryota | F4JLK2 | 826603 | 4 | Sucrose-phosphate synthase 4 (EC 2.4.1.14) | GT-B | Retaining | UDP-alpha-D-glucose | — |
| SQD2 | Arabidopsis thaliana | Eukaryota | Q8S4F6 | 831888 | 5 | Sulfoquinovosyl transferase SQD2 (EC 2.4.1.-) | GT-B | Retaining | UDP-alpha-D-6-sulfoquinovose | — |
| SUS1 | Arabidopsis thaliana | Eukaryota | P49040 | 832206 | 5 | Sucrose synthase 1 (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | 3S27, 3S28, 3S29 |
| SUS2 | Arabidopsis thaliana | Eukaryota | Q00917 | 834978 | 5 | Sucrose synthase 2 (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| SUS3 | Arabidopsis thaliana | Eukaryota | Q9M111 | 828081 | 5 | Sucrose synthase 3 (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| SUS4 | Arabidopsis thaliana | Eukaryota | Q9LXL5 | 823393 | 4 | Sucrose synthase 4 (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| SUS5 | Arabidopsis thaliana | Eukaryota | F4K5W8 | — | 4 | Sucrose synthase 5 (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| SUS6 | Arabidopsis thaliana | Eukaryota | Q9FX32 | 843672 | 5 | Sucrose synthase 6 (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| SUS1 | Oryza sativa subsp. japonica | Eukaryota | P31924 | — | 4 | Sucrose synthase 1 (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| SUS2 | Oryza sativa subsp. japonica | Eukaryota | P30298 | — | 5 | Sucrose synthase 2 (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| ALG11 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Eukaryota | P53954 | 855679 | 5 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) | GT-B | Retaining | 2 GDP-alpha-D-mannose | — |
| ALG2 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Eukaryota | P43636 | 852815 | 5 | Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132; 2.4.1.257) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| SPT14 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Eukaryota | P32363 | 855928 | 5 | Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit (EC 2.4.1.198) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | — |
| waaG | Escherichia coli (strain K12) | Bacteria | P25740 | 948149 | 5 | Lipopolysaccharide glucosyltransferase WaaG (EC 2.4.1.-) | GT-B | Retaining | — | 2IV7, 2IW1, 2N58 |
| wbdA | Escherichia coli | Bacteria | M4QN28 | — | 5 | Serotype-specific mannosyltransferase WbdA (EC 2.4.1.371) | GT-B | Retaining | 2 GDP-alpha-D-mannose | — |
| wbdA | Escherichia coli | Bacteria | Q47593 | — | 4 | Serotype-specific mannosyltransferase WbdA (EC 2.4.1.371) | GT-B | Retaining | 2 GDP-alpha-D-mannose | — |
| wclY | Escherichia coli | Bacteria | A6M9B7 | — | 5 | O-antigen biosynthesis glycosyltransferase WclY (EC 2.4.1.-) | GT-B | Retaining | — | — |
| wclY | Escherichia coli | Bacteria | B8QSK0 | — | 4 | O-antigen biosynthesis glycosyltransferase WclY (EC 2.4.1.-) | GT-B | Retaining | — | — |
| wbpZ | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | Bacteria | Q9HTC0 | 878012 | 5 | D-rhamnosyltransferase WbpZ (EC 2.4.1.-; 2.4.1.348) | GT-B | Retaining | GDP-alpha-D-rhamnose; GDP-alpha-D-mannose | — |
| bshA | Bacillus subtilis (strain 168) | Bacteria | P42982 | 939029 | 5 | N-acetyl-alpha-D-glucosaminyl L-malate synthase (EC 2.4.1.-) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | 5D00, 5D01 |
| tagE | Bacillus subtilis (strain 168) | Bacteria | P13484 | 936804 | 4 | Poly(glycerol-phosphate) alpha-glucosyltransferase (EC 2.4.1.52) | GT-B | Retaining | n UDP-alpha-D-glucose | — |
| tarM | Staphylococcus aureus (strain COL) | Bacteria | A0A0H2WWV6 | — | 5 | Poly(ribitol-phosphate) alpha-N-acetylglucosaminyltransferase (EC 2.4.1.70) | GT-B | Retaining | n UDP-N-acetyl-alpha-D-glucosamine | 4WAC, 4WAD, 4X6L… |
| mshA | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) | Bacteria | Q8NTA6 | 1021208 | 4 | D-inositol 3-phosphate glycosyltransferase (EC 2.4.1.250) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | 3C48, 3C4Q, 3C4V |
| pimB | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) | Bacteria | Q8NNK8 | 1020138 | 5 | GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase (EC 2.4.1.346) | GT-B | Retaining | GDP-alpha-D-mannose | 3OKA, 3OKC, 3OKP |
| dgs | Acholeplasma laidlawii | Bacteria | Q8KQL6 | 41338712 | 5 | Processive diacylglycerol alpha-glucosyltransferase (EC 2.4.1.208; 2.4.1.337) | GT-B | Retaining | UDP-alpha-D-glucose | — |
| mgs | Acholeplasma laidlawii | Bacteria | Q93P60 | — | 5 | Alpha-monoglucosyldiacylglycerol synthase (EC 2.4.1.337) | GT-B | Retaining | UDP-alpha-D-glucose | 1Z2T |
| bshA | Bacillus anthracis | Bacteria | Q81ST7 | 45021530 | 4 | N-acetyl-alpha-D-glucosaminyl L-malate synthase (EC 2.4.1.-) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | 2JJM, 3MBO |
| pglH | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | Bacteria | Q0P9C5 | 905420 | 5 | GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase (EC 2.4.1.292) | GT-B | Retaining | 3 UDP-N-acetyl-alpha-D-galactosamine | 6EJI, 6EJJ, 6EJK |
| ALG2 | Candida albicans (strain SC5314 / ATCC MYA-2876) | Eukaryota | Q59LF2 | 3647832 | 4 | Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132; 2.4.1.257) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| ALG2 | Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) | Eukaryota | Q6FJJ9 | 2891643 | 4 | Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132; 2.4.1.257) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| mshA | Corynebacterium timonense | Bacteria | A0A1H1T8X9 | — | 4 | Multifunctional fusion protein | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | — |
| Q9XGB7 | Gossypium hirsutum | Eukaryota | Q9XGB7 | — | 4 | Sucrose synthase (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| O75003 | Grifola frondosa | Eukaryota | O75003 | — | 5 | Trehalose phosphorylase (EC 2.4.1.231) | GT-B | Retaining | — | — |
| TP | Lentinus sajor-caju | Eukaryota | Q9UV63 | — | 4 | Trehalose phosphorylase (EC 2.4.1.231) | GT-B | Retaining | — | — |
| Alg2 | Mus musculus | Eukaryota | Q9DBE8 | 56737 | 4 | Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132; 2.4.1.257) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| Piga | Mus musculus | Eukaryota | Q64323 | 18700 | 4 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | — |
| glgM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Bacteria | P9WMZ1 | 887805 | 5 | Alpha-maltose-1-phosphate synthase (EC 2.4.1.342) | GT-B | Retaining | ADP-alpha-D-glucose | — |
| mshA | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Bacteria | P9WMY7 | 887160 | 4 | D-inositol 3-phosphate glycosyltransferase (EC 2.4.1.250) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | — |
| pimA | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Bacteria | P9WMZ5 | 45426613; 888627 | 5 | Phosphatidyl-myo-inositol mannosyltransferase (EC 2.4.1.345) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| pimB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Bacteria | P9WMZ3 | 887278 | 4 | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase (EC 2.4.1.346) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| pimC | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | Bacteria | P0CF99 | 45425730 | 4 | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase (EC 2.4.1.-) | GT-B | Retaining | — | — |
| manT | Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) | Bacteria | K5BE02 | — | 4 | MMP alpha-(1->4)-mannosyltransferase (EC 2.4.1.393) | GT-B | Retaining | GDP-alpha-D-mannose | 7QSG |
| pimA | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | Bacteria | A0QWG6 | 93457715 | 5 | Phosphatidyl-myo-inositol mannosyltransferase (EC 2.4.1.345) | GT-B | Retaining | GDP-alpha-D-mannose | 2GEJ, 2GEK, 4N9W… |
| pimB | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | Bacteria | A0R043 | — | 4 | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase (EC 2.4.1.346) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| ss2 | Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) | Bacteria | Q820M5 | 87104394 | 5 | Sucrose synthase (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose; ADP-alpha-D-glucose | 4RBN |
| treT | Rubrobacter xylanophilus (strain DSM 9941 / JCM 11954 / NBRC 16129 / PRD-1) | Bacteria | Q1ARU5 | — | 4 | Trehalose synthase (EC 2.4.1.245) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
| alg11 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | Eukaryota | O74878 | 2539054 | 4 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) | GT-B | Retaining | 2 GDP-alpha-D-mannose | — |
| alg2 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | Eukaryota | Q96WW6 | 2539854 | 4 | Alpha-1,3/1,6-mannosyltransferase alg2 (EC 2.4.1.132; 2.4.1.257) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| SPS1 | Spinacia oleracea | Eukaryota | P31928 | — | 4 | Sucrose-phosphate synthase (EC 2.4.1.14) | GT-B | Retaining | UDP-alpha-D-glucose | — |
| gtfA | Streptococcus agalactiae | Bacteria | Q3S2Y2 | 66886245 | 4 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase GtfA subunit (EC 2.4.1.-) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | — |
| gtfA | Streptococcus gordonii | Bacteria | Q9AET5 | — | 5 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase GtfA subunit (EC 2.4.1.-) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | 5E9T, 5E9U |
| gtfA | Streptococcus parasanguinis | Bacteria | A1C3L9 | — | 5 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase GtfA subunit (EC 2.4.1.-) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | — |
| gtfA | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | Bacteria | A0A0H2URG7 | — | 5 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase GtfA subunit (EC 2.4.1.-) | GT-B | Retaining | UDP-N-acetyl-alpha-D-glucosamine | 4PQG |
| kanE | Streptomyces kanamyceticus | Bacteria | Q65CC7 | — | 4 | Alpha-D-kanosaminyltransferase (EC 2.4.1.301) | GT-B | Retaining | UDP-alpha-D-kanosamine | — |
| susA | Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1) | Bacteria | Q8DK23 | — | 4 | Sucrose synthase (EC 2.4.1.13) | GT-B | Retaining | an NDP-alpha-D-glucose; ADP-alpha-D-glucose | — |
| glgA | Velamenicoccus archaeovorus | Bacteria | A0A410P257 | — | 5 | Glycogen synthase (EC 2.4.1.21) | GT-B | Retaining | ADP-alpha-D-glucose | — |
| ALG2 | Yarrowia lipolytica (strain CLIB 122 / E 150) | Eukaryota | Q6C3V7 | — | 4 | Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132; 2.4.1.257) | GT-B | Retaining | GDP-alpha-D-mannose | — |
| treT | Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) | Archaea | Q7LYW5 | 13300540; 16548946 | 4 | Trehalose synthase (EC 2.4.1.245) | GT-B | Retaining | an NDP-alpha-D-glucose | — |
Row colour key
Model-organism entry with UniProt annotation level 4 or 5.
Non-model organism entry, annotation level 4–5.
Lower annotation level (1–3) or level unspecified.