GT-CORE (public beta v1)

Glycosyltransferase Curated Online Resource for Enzymology

Family-organised sequence, structure, mechanism and substrate-specificity records for the CAZy glycosyltransferases

pimC

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) · GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase (EC 2.4.1.-)

GT4Non-model organism · annotation 4–5Fold GT-BRetaining

External resources

Identification and annotation

CAZy familyGT4 · CAZy entry
Gene symbolpimC
Synonyms / alternate names
  • RvD2-ORF1
  • Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase
  • Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase
  • Phosphatidylinositol alpha-mannosyltransferase
UniProt accessionP0CF99
NCBI Gene ID45425730
Source speciesMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Taxonomic domainBacteria
UniProt annotation level4

Function and localisation

Enzyme functionGDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase (EC 2.4.1.-)
Subcellular locationnot curated

Structure and mechanism

Fold typeGT-B
Catalytic mechanismRetaining
Cation dependenceNo
Oligomeric statenot curated
PDB structuresnot curated

Donor and acceptor specificity

Sugar nucleotide donornot curated
Donor CCD code(s)not curated
Acceptor substrate(s)not curated
Acceptor CCD / GlycoCTnot curated

Protein sequences

Full protein sequence

381 aa
MRVVQVANFYGPRSGGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPAKHIPYTGGYRAVMPGAVRTVLETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREEFDRIGATNTVTVPLGVDLKTFHPRRRCARVRQHWATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGPLRARLERKATGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLACGTPAVVSRTSALTEIITADSGACADNRPEAIAHAVRTIVSRPERHRRRCARRRAEIFTWQRAAASMLATLGAMAVSTRCGDTQDTA

Catalytic domain sequence

161 aa
GGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPAKHIPYTGGYRAVMPGAVRTVLETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREEFDRIGATNTVTVPLG