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manT
Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) · MMP alpha-(1->4)-mannosyltransferase (EC 2.4.1.393)
GT4Non-model organism · annotation 4–5Fold GT-BRetaining1 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT4 · CAZy entry |
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| Gene symbol | manT |
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| Synonyms / alternate names | not curated |
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| UniProt accession | K5BE02 |
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| NCBI Gene ID | not curated |
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| Source species | Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | MMP alpha-(1->4)-mannosyltransferase (EC 2.4.1.393) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Retaining |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | 7QSG |
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Donor and acceptor specificity
| Sugar nucleotide donor | GDP-alpha-D-mannose |
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| Donor CCD code(s) | GDD |
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| Acceptor substrate(s) | - [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-3-O-methyl-D-mannose
- [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-1-O,3-O-dimethyl-alpha-D-mannose
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
411 aa
MRIALLSYRSKTHCGGQGVYVRHLSRELAELGHDVEVFSGQPYPEGLDPRVRLTKVPSLDLYREPDPFRIPRPSEIKTSIDLEELLTTWTAGFPEPKTFSLRAARVLAGRRGDFDVVHDNQCLGTGLLQIAKMGFPLVATVHHPITRDREVEVAAARWWRKPLVRRWYGFVEMQKRVARQIPELLTVSSASASDILTDFAVSPEQLHVVPLGVDTKLFQPREGRVRNRIIAIASADVPLKGVSHLLHAVARLRVERDVELQLVTKLEPNGPTEKLIAELGISDIVHTSSGLSDEELAALLASAEVACIPSLYEGFSLPAVEAMASGTPIVASRAGALPEVVGPDGECARLVTPADVDELTAVLGRLLDSPRELRRLGDNGRRRAVEVFSWQSVAAQTVAVYEKAIARVAAC
Catalytic domain sequence
401 aa
RIALLSYRSKTHCGGQGVYVRHLSRELAELGHDVEVFSGQPYPEGLDPRVRLTKVPSLDLYREPDPFRIPRPSEIKTSIDLEELLTTWTAGFPEPKTFSLRAARVLAGRRGDFDVVHDNQCLGTGLLQIAKMGFPLVATVHHPITRDREVEVAAARWWRKPLVRRWYGFVEMQKRVARQIPELLTVSSASASDILTDFAVSPEQLHVVPLGVDTKLFQPREGRVRNRIIAIASADVPLKGVSHLLHAVARLRVERDVELQLVTKLEPNGPTEKLIAELGISDIVHTSSGLSDEELAALLASAEVACIPSLYEGFSLPAVEAMASGTPIVASRAGALPEVVGPDGECARLVTPADVDELTAVLGRLLDSPRELRRLGDNGRRRAVEVFSWQSVAAQTVAVYE
