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treT
Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) · Trehalose synthase (EC 2.4.1.245)
GT4Non-model organism · annotation 4–5Fold GT-BRetaining
External resources
Identification and annotation
| CAZy family | GT4 · CAZy entry |
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| Gene symbol | treT |
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| Synonyms / alternate names | Trehalose glycosyltransferring synthase |
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| UniProt accession | Q7LYW5 |
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| NCBI Gene ID | 13300540; 16548946 |
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| Source species | Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) |
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| Taxonomic domain | Archaea |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Trehalose synthase (EC 2.4.1.245) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Retaining |
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| Cation dependence | Yes (Mg2+) |
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| Oligomeric state | homodimer |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | an NDP-alpha-D-glucose |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | D-glucose |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
412 aa
MYEVTKFGGEGKRLEDYREIIGDEALEAIKAKAENLKDKSFVHVNSTSFGGGVAEILHNLVPLMRDVGIDARWFVIEGTNEFFNVTKSFHNALQGNKELRLTEEMKKLYLEINKKNAEDIDLTQFDYVLIHDPQPAPLIEFYEKRQPWIWRCHIDLSDPNLEFWKFLRQFVEKYDRYIFHMEEYVQEDLNQEKVVIMPPSIDPLSEKNMELSESEILKTLERFDVDPERPIITQVARFDPWKGVFDVIDVYRKVKEKIPEVQLLLVGVMAHDDPEGWIYFEKTLRKIGEDYDIKVLTNLTGVHAREVNAFQRASDVILQMSIREGFGLTVTEAMWKEKPVVGRAVGGIKLQIVDGKTGFLVKDVNDAIEKTLYLLEHKDVAQEMGKNAKERIKENFIITKHLERYLDLLNSF
Catalytic domain sequence
167 aa
VDPERPIITQVARFDPWKGVFDVIDVYRKVKEKIPEVQLLLVGVMAHDDPEGWIYFEKTLRKIGEDYDIKVLTNLTGVHAREVNAFQRASDVILQMSIREGFGLTVTEAMWKEKPVVGRAVGGIKLQIVDGKTGFLVKDVNDAIEKTLYLLEHKDVAQEMGKNAKER
