Home/GT Families/GT4/pimB
pimB
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) · GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase (EC 2.4.1.346)
GT4Model organism · annotation ≥ 4Fold GT-BRetaining3 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT4 · CAZy entry |
|---|
| Gene symbol | pimB |
|---|
| Synonyms / alternate names | - Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase
- Alpha-mannosyltransferase
- Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase
- Phosphatidylinositol alpha-mannosyltransferase
|
|---|
| UniProt accession | Q8NNK8 |
|---|
| NCBI Gene ID | 1020138 |
|---|
| Source species | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) |
|---|
| Taxonomic domain | Bacteria |
|---|
| UniProt annotation level | 5 |
|---|
Function and localisation
| Enzyme function | GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase (EC 2.4.1.346) |
|---|
| Subcellular location | not curated |
|---|
Structure and mechanism
| Fold type | GT-B |
|---|
| Catalytic mechanism | Retaining |
|---|
| Cation dependence | No |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | 3OKA, 3OKC, 3OKP |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | GDP-alpha-D-mannose |
|---|
| Donor CCD code(s) | GDD |
|---|
| Acceptor substrate(s) | - a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol]
- a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol]
|
|---|
| Acceptor CCD / GlycoCT | INS Verified PDB CCD code |
|---|
Protein sequences
Full protein sequence
381 aa
MSASRKTLVVTNDFPPRIGGIQSYLRDFIATQDPESIVVFASTQNAEEAHAYDKTLDYEVIRWPRSVMLPTPTTAHAMAEIIREREIDNVWFGAAAPLALMAGTAKQAGASKVIASTHGHEVGWSMLPGSRQSLRKIGTEVDVLTYISQYTLRRFKSAFGSHPTFEHLPSGVDVKRFTPATPEDKSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRYESTLRRLATDVSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQACGVPVIAGTSGGAPETVTPATGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRAHVEAEWSWEIMGERLTNILQSEPR
Catalytic domain sequence
173 aa
KSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRYESTLRRLATDVSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQACGVPVIAGTSGGAPETVTPATGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRA
