Home/GT Families/GT50/PIGM
PIGM
Trypanosoma brucei brucei (strain 927/4 GUTat10.1) · GPI mannosyltransferase 1 (EC 2.4.1.-)
GT50Non-model organism · annotation 4–5Fold GT-CInverting
External resources
Identification and annotation
| CAZy family | GT50 · CAZy entry |
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| Gene symbol | PIGM |
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| Synonyms / alternate names | - GPI mannosyltransferase I
- Phosphatidylinositol-glycan biosynthesis class M protein
- TbPIG-M
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| UniProt accession | Q9BPQ5 |
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| NCBI Gene ID | 3657966 |
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| Source species | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | GPI mannosyltransferase 1 (EC 2.4.1.-) |
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| Subcellular location | Endoplasmic reticulum membrane |
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Structure and mechanism
| Fold type | GT-C |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | not curated |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
430 aa
MELQSLIDTVSLQKLLLLGALLRLILIAYAFFHDQWFRVKYTDIDYMIVVDGARHMWNGGSPFDRTTFRYTPLLAALVMPSIWIANPMGKLIFASSDLGAAWYCYGVLKSFAKERSAKWMVSLFILFNPIVLSVSTRGNSDMLVTFMSLMVLSKFARRKCYQAAAVLGFAVHFKIYPIIYALPLTLGVWEQSVAASTNTWRRVVKTAVVVSICALMAAISFAVPTVLCYMKYGQQYLNEAFIYHVYREDHRHNFSPYWLLMYLNMARRHLGQGVDFSPRLVAFAPQAVVLSFVSYKLRRNTAHACCVQTVLFVAFNKVCTVQYFVWFIPFLAFLFCEPKEVEDDESGGSGAFKFFSWVKALGVVLMWAATIPLWVTTAVPLEFHGYSDFAQLWIVSCLFFLAMVVLASMLARIAYRVQCTKCSAKSIKVA
Catalytic domain sequence
277 aa
VSTRGNSDMLVTFMSLMVLSKFARRKCYQAAAVLGFAVHFKIYPIIYALPLTLGVWEQSVAASTNTWRRVVKTAVVVSICALMAAISFAVPTVLCYMKYGQQYLNEAFIYHVYREDHRHNFSPYWLLMYLNMARRHLGQGVDFSPRLVAFAPQAVVLSFVSYKLRRNTAHACCVQTVLFVAFNKVCTVQYFVWFIPFLAFLFCEPKEVEDDESGGSGAFKFFSWVKALGVVLMWAATIPLWVTTAVPLEFHGYSDFAQLWIVSCLFFLAMVVLASML
